Arjen Scholten
Arjen Scholten
Principal Scientist Analytical Development; Janssen Vaccines & Prevention
Verified email at
Cited by
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On terminal alkynes that can react with active-site cysteine nucleophiles in proteases
R Ekkebus, SI van Kasteren, Y Kulathu, A Scholten, I Berlin, PP Geurink, ...
Journal of the American Chemical Society 135 (8), 2867-2870, 2013
Revealing promiscuous drug–target interactions by chemical proteomics
M Bantscheff, A Scholten, AJR Heck
Drug discovery today 14 (21-22), 1021-1029, 2009
Analysis of the cGMP/cAMP interactome using a chemical proteomics approach in mammalian heart tissue validates sphingosine kinase type 1-interacting protein as a genuine and …
A Scholten, MK Poh, TAB van Veen, B van Breukelen, MA Vos, AJR Heck
Journal of proteome research 5 (6), 1435-1447, 2006
Human CD62Ldim neutrophils identified as a separate subset by proteome profiling and in vivo pulse-chase labeling
T Tak, P Wijten, M Heeres, P Pickkers, A Scholten, AJR Heck, ...
Blood, The Journal of the American Society of Hematology 129 (26), 3476-3485, 2017
High precision platelet releasate definition by quantitative reversed protein profiling—brief report
P Wijten, T van Holten, LL Woo, OB Bleijerveld, M Roest, AJR Heck, ...
Arteriosclerosis, thrombosis, and vascular biology 33 (7), 1635-1638, 2013
Sphingosine kinase interacting protein is an A‐kinase anchoring protein specific for type I cAMP‐dependent protein kinase
D Kovanich, MAG Van Der Heyden, TT Aye, TAB Van Veen, AJR Heck, ...
Chembiochem 11 (7), 963-971, 2010
Protease bias in absolute protein quantitation
M Peng, N Taouatas, S Cappadona, B Van Breukelen, S Mohammed, ...
Nature methods 9 (6), 524-525, 2012
cGMP-binding prepares PKG for substrate binding by disclosing the C-terminal domain
V Alverdi, H Mazon, C Versluis, W Hemrika, G Esposito, ...
Journal of molecular biology 375 (5), 1380-1393, 2008
A small novel A-kinase anchoring protein (AKAP) that localizes specifically protein kinase A-regulatory subunit I (PKA-RI) to the plasma membrane
PP Burgers, Y Ma, L Margarucci, M Mackey, MAG van der Heyden, ...
Journal of Biological Chemistry 287 (52), 43789-43797, 2012
Reorganized PKA-AKAP associations in the failing human heart
TT Aye, S Soni, TAB van Veen, MAG van der Heyden, S Cappadona, ...
Journal of molecular and cellular cardiology 52 (2), 511-518, 2012
SPEG (striated muscle preferentially expressed protein kinase) is essential for cardiac function by regulating junctional membrane complex activity
AP Quick, Q Wang, LE Philippen, G Barreto-Torres, DY Chiang, ...
Circulation research 120 (1), 110-119, 2017
Applications of stable isotope dimethyl labeling in quantitative proteomics
D Kovanich, S Cappadona, R Raijmakers, S Mohammed, A Scholten, ...
Analytical and bioanalytical chemistry 404, 991-1009, 2012
Proteome-wide protein concentrations in the human heart
TT Aye, A Scholten, N Taouatas, A Varro, TAB Van Veen, MA Vos, ...
Molecular BioSystems 6 (10), 1917-1927, 2010
Quantitative proteomics analysis reveals similar release profiles following specific PAR-1 or PAR-4 stimulation of platelets
TC van Holten, OB Bleijerveld, P Wijten, PG de Groot, AJR Heck, ...
Cardiovascular research 103 (1), 140-146, 2014
Diversity of cAMP-dependent protein kinase isoforms and their anchoring proteins in mouse ventricular tissue
A Scholten, TAB van Veen, MA Vos, AJR Heck
Journal of proteome research 6 (5), 1705-1717, 2007
Selectivity in Enrichment of cAMP-dependent Protein Kinase Regulatory Subunits Type I and Type II and Their Interactors Using Modified cAMP Affinity Resins* S
TT Aye, S Mohammed, HWP van den Toorn, TAB van Veen, ...
Molecular & Cellular Proteomics 8 (5), 1016-1028, 2009
Interrogating cAMP-dependent kinase signaling in Jurkat T cells via a protein kinase A targeted immune-precipitation phosphoproteomics approach
P Giansanti, MP Stokes, JC Silva, A Scholten, AJR Heck
Molecular & Cellular Proteomics 12 (11), 3350-3359, 2013
Identification of enriched PTM crosstalk motifs from large-scale experimental data sets
M Peng, A Scholten, AJR Heck, B van Breukelen
Journal of proteome research 13 (1), 249-259, 2014
Surface‐Plasmon‐Resonance‐Based Chemical Proteomics: Efficient Specific Extraction and Semiquantitative Identification of Cyclic Nucleotide‐Binding Proteins from Cellular …
NFC Visser, A Scholten, RHH van den Heuvel, AJR Heck
ChemBioChem 8 (3), 298-305, 2007
Alterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients
DY Chiang, N Lebesgue, DL Beavers, KM Alsina, JMA Damen, N Voigt, ...
Journal of the American College of Cardiology 65 (2), 163-173, 2015
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