| SIRT1 transgenic mice show phenotypes resembling calorie restriction L Bordone, D Cohen, A Robinson, MC Motta, E Van Veen, A Czopik, ... Aging cell 6 (6), 759-767, 2007 | 880 | 2007 |
| Increase in activity during calorie restriction requires Sirt1 D Chen, AD Steele, S Lindquist, L Guarente Science 310 (5754), 1641-1641, 2005 | 546 | 2005 |
| Axonal prion protein is required for peripheral myelin maintenance J Bremer, F Baumann, C Tiberi, C Wessig, H Fischer, P Schwarz, ... Nature neuroscience 13 (3), 310-318, 2010 | 508 | 2010 |
| Prion protein (PrPc) positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesis AD Steele, JG Emsley, PH Özdinler, S Lindquist, JD Macklis Proceedings of the National Academy of Sciences 103 (9), 3416-3421, 2006 | 406 | 2006 |
| Automated home-cage behavioural phenotyping of mice H Jhuang, E Garrote, X Yu, V Khilnani, T Poggio, AD Steele, T Serre Nature communications 1 (1), 68, 2010 | 357 | 2010 |
| Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal CC Zhang, AD Steele, S Lindquist, HF Lodish Proceedings of the National Academy of Sciences 103 (7), 2184-2189, 2006 | 352 | 2006 |
| The prion protein knockout mouse: a phenotype under challenge AD Steele, S Lindquist, A Aguzzi Prion 1 (2), 83-93, 2007 | 216 | 2007 |
| The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases AD Steele, WS Jackson, OD King, S Lindquist Proceedings of the National Academy of Sciences 104 (6), 1983-1988, 2007 | 216 | 2007 |
| Spontaneous generation of prion infectivity in fatal familial insomnia knockin mice WS Jackson, AW Borkowski, H Faas, AD Steele, OD King, N Watson, ... Neuron 63 (4), 438-450, 2009 | 187 | 2009 |
| Cholinergic modulation of locomotion and striatal dopamine release is mediated by α6α4* nicotinic acetylcholine receptors RM Drenan, SR Grady, AD Steele, S McKinney, NE Patzlaff, JM McIntosh, ... Journal of Neuroscience 30 (29), 9877-9889, 2010 | 151 | 2010 |
| Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease JL Wacker, SY Huang, AD Steele, R Aron, GP Lotz, QV Nguyen, ... Journal of Neuroscience 29 (28), 9104-9114, 2009 | 128 | 2009 |
| Dopamine receptor 1 neurons in the dorsal striatum regulate food anticipatory circadian activity rhythms in mice CM Gallardo, M Darvas, M Oviatt, CH Chang, M Michalik, TF Huddy, ... Elife 3, e03781, 2014 | 114 | 2014 |
| The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration D Chen, AD Steele, G Hutter, J Bruno, A Govindarajan, E Easlon, SJ Lin, ... Experimental gerontology 43 (12), 1086-1093, 2008 | 89 | 2008 |
| Deletion of densin-180 results in abnormal behaviors associated with mental illness and reduces mGluR5 and DISC1 in the postsynaptic density fraction HJ Carlisle, TN Luong, A Medina-Marino, L Schenker, E Khorosheva, ... Journal of Neuroscience 31 (45), 16194-16207, 2011 | 84 | 2011 |
| Palatable meal anticipation in mice CT Hsu, DF Patton, RE Mistlberger, AD Steele PloS one 5 (9), e12903, 2010 | 84 | 2010 |
| Direct and selective elimination of specific prions and amyloids by 4, 5-dianilinophthalimide and analogs H Wang, ML Duennwald, BE Roberts, LM Rozeboom, YL Zhang, ... Proceedings of the National Academy of Sciences 105 (20), 7159-7164, 2008 | 83 | 2008 |
| Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease AD Steele, G Hutter, WS Jackson, FL Heppner, AW Borkowski, OD King, ... Proceedings of the National Academy of Sciences 105 (36), 13626-13631, 2008 | 79 | 2008 |
| Single gene deletions of orexin, leptin, neuropeptide Y, and ghrelin do not appreciably alter food anticipatory activity in mice KM Gunapala, CM Gallardo, CT Hsu, AD Steele PloS one 6 (3), e18377, 2011 | 75 | 2011 |
| Prion pathogenesis is independent of caspase-12 AD Steele, C Hetz, CH Yi, WS Jackson, AW Borkowski, J Yuan, ... Prion 1 (4), 243-247, 2007 | 60 | 2007 |
| Dopamine signaling in the suprachiasmatic nucleus enables weight gain associated with hedonic feeding RM Grippo, Q Tang, Q Zhang, SR Chadwick, Y Gao, EB Altherr, L Sipe, ... Current Biology 30 (2), 196-208. e8, 2020 | 51 | 2020 |
