Nico Zinn
Nico Zinn
Cellzome GmbH, a GSK company
Verified email at
Cited by
Cited by
Catalytic in vivo protein knockdown by small-molecule PROTACs
DP Bondeson, A Mares, IED Smith, E Ko, S Campos, AH Miah, ...
Nature chemical biology 11 (8), 611-617, 2015
Systematic analysis of protein turnover in primary cells
T Mathieson, H Franken, J Kosinski, N Kurzawa, N Zinn, G Sweetman, ...
Nature communications 9 (1), 689, 2018
Measuring and managing ratio compression for accurate iTRAQ/TMT quantification
MM Savitski, T Mathieson, N Zinn, G Sweetman, C Doce, I Becher, ...
Journal of proteome research 12 (8), 3586-3598, 2013
De novo sequencing of peptides by MS/MS
J Seidler, N Zinn, ME Boehm, WD Lehmann
Proteomics 10 (4), 634-649, 2010
Biological plasticity rescues target activity in CRISPR knock outs
AH Smits, F Ziebell, G Joberty, N Zinn, WF Mueller, S Clauder-Münster, ...
Nature methods 16 (11), 1087-1093, 2019
Multiplexed proteome dynamics profiling reveals mechanisms controlling protein homeostasis
MM Savitski, N Zinn, M Faelth-Savitski, D Poeckel, S Gade, I Becher, ...
Cell 173 (1), 260-274. e25, 2018
Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson’s disease-related toxicity in human neurons
N Ramsden, J Perrin, Z Ren, BD Lee, N Zinn, VL Dawson, D Tam, M Bova, ...
ACS chemical biology 6 (10), 1021-1028, 2011
The mTORC1/4E-BP1 axis represents a critical signaling node during fibrogenesis
HV Woodcock, JD Eley, D Guillotin, M Platé, CB Nanthakumar, M Martufi, ...
Nature communications 10 (1), 6, 2019
Extended pharmacodynamic responses observed upon PROTAC-mediated degradation of RIPK2
A Mares, AH Miah, IED Smith, M Rackham, AR Thawani, J Cryan, ...
Communications biology 3 (1), 140, 2020
Delayed fragmentation and optimized isolation width settings for improvement of protein identification and accuracy of isobaric mass tag quantification on Orbitrap-type mass …
MM Savitski, G Sweetman, M Askenazi, JA Marto, M Lang, N Zinn, ...
Analytical chemistry 83 (23), 8959-8967, 2011
Discovery of GSK8612, a highly selective and potent TBK1 inhibitor
DW Thomson, D Poeckel, N Zinn, C Rau, K Strohmer, AJ Wagner, ...
ACS medicinal chemistry letters 10 (5), 780-785, 2019
Discovery and characterisation of highly cooperative FAK‐degrading PROTACs
RP Law, J Nunes, C Chung, M Bantscheff, K Buda, H Dai, JP Evans, ...
Angewandte Chemie International Edition 60 (43), 23327-23334, 2021
Protein labelling with mercury tags: fundamental studies on ovalbumin derivatised with p-hydroxymercuribenzoic acid (pHMB)
DJ Kutscher, ME del Castillo Busto, N Zinn, A Sanz-Medel, J Bettmer
Journal of Analytical Atomic Spectrometry 23 (10), 1359-1364, 2008
μLC coupled to ICP–SFMS with post-column isotope dilution analysis of sulfur for absolute protein quantification
N Zinn, R Krüger, P Leonhard, J Bettmer
Analytical and bioanalytical chemistry 391, 537-543, 2008
Phosphorus-based absolutely quantified standard peptides for quantitative proteomics
N Zinn, B Hahn, R Pipkorn, D Schwarzer, WD Lehmann
Journal of Proteome Research 8 (10), 4870-4875, 2009
Recombinant isotope labeled and selenium quantified proteins for absolute protein quantification
N Zinn, D Winter, WD Lehmann
Analytical chemistry 82 (6), 2334-2340, 2010
Gel Electrophoresis Coupled to Inductively Coupled Plasma− Mass Spectrometry Using Species-Specific Isotope Dilution for Iodide and Iodate Determination in Aerosols
W Brüchert, A Helfrich, N Zinn, T Klimach, M Breckheimer, H Chen, S Lai, ...
Analytical chemistry 79 (4), 1714-1719, 2007
Improved proteomics-based drug mechanism-of-action studies using 16-Plex isobaric mass tags
N Zinn, T Werner, C Doce, T Mathieson, C Boecker, G Sweetman, ...
Journal of Proteome Research 20 (3), 1792-1801, 2021
Metal ion-mobilizing additives for comprehensive detection of femtomole amounts of phosphopeptides by reversed phase LC-MS
J Seidler, N Zinn, E Haaf, ME Boehm, D Winter, A Schlosser, ...
Amino Acids 41, 311-320, 2011
Mass spectrometry approaches to monitor protein–drug interactions
N Zinn, C Hopf, G Drewes, M Bantscheff
Methods 57 (4), 430-440, 2012
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