Nils Kurzawa
Nils Kurzawa
Cellzome, a GSK company
Verified email at
Cited by
Cited by
Systematic analysis of protein turnover in primary cells
T Mathieson*, H Franken*, J Kosinski*, N Kurzawa*, N Zinn, G Sweetman, ...
Nature communications 9 (1), 1-10, 2018
Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP
S Sridharan*, N Kurzawa*, T Werner, I Günthner, D Helm, W Huber, ...
Nature communications 10 (1), 1-13, 2019
Pervasive protein thermal stability variation during the cell cycle
I Becher, A Andrés-Pons, N Romanov, F Stein, M Schramm, F Baudin, ...
Cell 173 (6), 1495-1507. e18, 2018
Meltome atlas—thermal proteome stability across the tree of life
A Jarzab*, N Kurzawa*, T Hopf*, M Moerch, J Zecha, N Leijten, Y Bian, ...
Nature methods 17 (5), 495-503, 2020
Thermal proteome profiling for interrogating protein interactions
A Mateus*, N Kurzawa*, I Becher, S Sridharan, D Helm, F Stein, A Typas, ...
Molecular Systems Biology 16 (3), e9232, 2020
Thermal proteome profiling in bacteria: probing protein state in vivo
A Mateus, J Bobonis, N Kurzawa, F Stein, D Helm, J Hevler, A Typas, ...
Molecular Systems Biology 14 (7), e8242, 2018
A comprehensive comparison of tools for differential ChIP-seq analysis
S Steinhauser, N Kurzawa, R Eils, C Herrmann
Briefings in bioinformatics, bbv110, 2016
Identifying drug targets in tissues and whole blood with thermal-shift profiling
J Perrin*, T Werner*, N Kurzawa*, A Rutkowska, DD Childs, M Kalxdorf, ...
Nature Biotechnology 38 (3), 303-308, 2020
Nonparametric Analysis of Thermal Proteome Profiles Reveals Novel Drug-binding Proteins
D Childs, K Bach, H Franken, S Anders, N Kurzawa, M Bantscheff, ...
Molecular & Cellular Proteomics 18 (12), 2506-2515, 2019
Impact of phosphorylation on thermal stability of proteins
CM Potel*, N Kurzawa*, I Becher*, A Typas, A Mateus, MM Savitski
Nature Methods, 1-3, 2021
The functional proteome landscape of Escherichia coli
A Mateus, J Hevler, J Bobonis, N Kurzawa, M Shah, K Mitosch, ...
Nature 588 (7838), 473-478, 2020
Cell surface thermal proteome profiling tracks perturbations and drug targets on the plasma membrane
M Kalxdorf, I Günthner, I Becher, N Kurzawa, S Knecht, MM Savitski, ...
Nature Methods 18, 84-91, 2021
Creating functional engineered variants of the single-module non-ribosomal peptide synthetase IndC by T domain exchange
R Beer, K Herbst, N Ignatiadis, I Kats, L Adlung, H Meyer, D Niopek, ...
Molecular BioSystems 10 (7), 1709-1718, 2014
Systematic discovery of biomolecular condensate-specific protein phosphorylation
S Sridharan, A Hernandez-Armendariz, N Kurzawa, CM Potel, D Memon, ...
Nature Chemical Biology 18 (10), 1104-1114, 2022
Dissecting the sequence determinants for dephosphorylation by the catalytic subunits of phosphatases PP1 and PP2A
B Hoermann, T Kokot, D Helm, S Heinzlmeir, JE Chojnacki, T Schubert, ...
Nature Communications 11 (1), 3583, 2020
Drug Target Identification in Tissues by Thermal Proteome Profiling
A Mateus*, N Kurzawa*, J Perrin, G Bergamini, MM Savitski
Annual Review of Pharmacology and Toxicology 62, 2022, 2022
A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles
N Kurzawa*, I Becher*, S Sridharan, H Franken, A Mateus, S Anders, ...
Nature Communications 11 (1), 1-8, 2020
SARS‐CoV‐2 infection remodels the host protein thermal stability landscape
J Selkrig, M Stanifer, A Mateus, K Mitosch, I Barrio‐Hernandez, M Rettel, ...
Molecular Systems Biology 17 (2), e10188, 2021
Aggregation and disaggregation features of the human proteome
TA Määttä, M Rettel, S Sridharan, D Helm, N Kurzawa, F Stein, ...
Molecular Systems Biology 16 (10), e9500, 2020
Rtpca: an R package for differential thermal proximity coaggregation analysis
N Kurzawa, A Mateus, MM Savitski
Bioinformatics 37 (3), 431-433, 2021
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Articles 1–20