Mitochondrial dynamics controls T cell fate through metabolic programming MD Buck, D O’Sullivan, RIK Geltink, JD Curtis, CH Chang, DE Sanin, ... Cell 166 (1), 63-76, 2016 | 1286 | 2016 |
Multi-stage differentiation defines melanoma subtypes with differential vulnerability to drug-induced iron-dependent oxidative stress J Tsoi, L Robert, K Paraiso, C Galvan, KM Sheu, J Lay, DJL Wong, M Atefi, ... Cancer cell 33 (5), 890-904. e5, 2018 | 717 | 2018 |
A unifying model for the selective regulation of inducible transcription by CpG islands and nucleosome remodeling VR Ramirez-Carrozzi, D Braas, DM Bhatt, CS Cheng, C Hong, KR Doty, ... Cell 138 (1), 114-128, 2009 | 675 | 2009 |
The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR RM Chin, X Fu, MY Pai, L Vergnes, H Hwang, G Deng, S Diep, ... Nature 510 (7505), 397-401, 2014 | 647 | 2014 |
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor AS Krall, S Xu, TG Graeber, D Braas, HR Christofk Nature communications 7 (1), 1-13, 2016 | 489 | 2016 |
Etomoxir inhibits macrophage polarization by disrupting CoA homeostasis AS Divakaruni, WY Hsieh, L Minarrieta, TN Duong, KKO Kim, ... Cell metabolism 28 (3), 490-503. e7, 2018 | 313 | 2018 |
Glycolytic metabolism plays a functional role in regulating human pluripotent stem cell state W Gu, X Gaeta, A Sahakyan, AB Chan, CS Hong, R Kim, D Braas, K Plath, ... Cell stem cell 19 (4), 476-490, 2016 | 276 | 2016 |
Nuclear localization of mitochondrial TCA cycle enzymes as a critical step in mammalian zygotic genome activation R Nagaraj, MS Sharpley, F Chi, D Braas, Y Zhou, R Kim, AT Clark, ... Cell 168 (1), 210-223. e11, 2017 | 273 | 2017 |
Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication M Thai, NA Graham, D Braas, M Nehil, E Komisopoulou, SK Kurdistani, ... Cell metabolism 19 (4), 694-701, 2014 | 271 | 2014 |
Lactate dehydrogenase activity drives hair follicle stem cell activation A Flores, J Schell, AS Krall, D Jelinek, M Miranda, M Grigorian, D Braas, ... Nature cell biology 19 (9), 1017-1026, 2017 | 264 | 2017 |
α-Ketoglutarate accelerates the initial differentiation of primed human pluripotent stem cells T TeSlaa, AC Chaikovsky, I Lipchina, SL Escobar, K Hochedlinger, ... Cell metabolism 24 (3), 485-493, 2016 | 261 | 2016 |
2-Hydroxyglutarate inhibits ATP synthase and mTOR signaling X Fu, RM Chin, L Vergnes, H Hwang, G Deng, Y Xing, MY Pai, S Li, L Ta, ... Cell metabolism 22 (3), 508-515, 2015 | 253 | 2015 |
Metabolic gatekeeper function of B-lymphoid transcription factors LN Chan, Z Chen, D Braas, JW Lee, G Xiao, H Geng, KN Cosgun, C Hurtz, ... Nature 542 (7642), 479-483, 2017 | 224 | 2017 |
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis Y Qing, L Dong, L Gao, C Li, Y Li, L Han, E Prince, B Tan, X Deng, ... Molecular cell 81 (5), 922-939. e9, 2021 | 222 | 2021 |
Doxycycline alters metabolism and proliferation of human cell lines E Ahler, WJ Sullivan, A Cass, D Braas, AG York, SJ Bensinger, ... PloS one 8 (5), e64561, 2013 | 218 | 2013 |
MCT1 modulates cancer cell pyruvate export and growth of tumors that co-express MCT1 and MCT4 CS Hong, NA Graham, W Gu, CE Camacho, V Mah, EL Maresh, M Alavi, ... Cell reports 14 (7), 1590-1601, 2016 | 217 | 2016 |
Extracellular matrix remodeling regulates glucose metabolism through TXNIP destabilization WJ Sullivan, PJ Mullen, EW Schmid, A Flores, M Momcilovic, MS Sharpley, ... Cell 175 (1), 117-132. e21, 2018 | 213 | 2018 |
mTORC2 regulates amino acid metabolism in cancer by phosphorylation of the cystine-glutamate antiporter xCT Y Gu, CP Albuquerque, D Braas, W Zhang, GR Villa, J Bi, S Ikegami, ... Molecular cell 67 (1), 128-138. e7, 2017 | 181 | 2017 |
Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis H Nakano, I Minami, D Braas, H Pappoe, X Wu, A Sagadevan, L Vergnes, ... Elife 6, e29330, 2017 | 174 | 2017 |
The GSK3 signaling axis regulates adaptive glutamine metabolism in lung squamous cell carcinoma M Momcilovic, ST Bailey, JT Lee, MC Fishbein, D Braas, J Go, ... Cancer cell 33 (5), 905-921. e5, 2018 | 171 | 2018 |