Regulatory T cells and inhibitory cytokines in autoimmunity M Bettini, DAA Vignali Current opinion in immunology 21 (6), 612-618, 2009 | 360 | 2009 |
Cutting edge: accelerated autoimmune diabetes in the absence of LAG-3 M Bettini, AL Szymczak-Workman, K Forbes, AH Castellaw, M Selby, ... The Journal of Immunology 187 (7), 3493-3498, 2011 | 196 | 2011 |
Paradoxical anti-inflammatory actions of TNF-α: inhibition of IL-12 and IL-23 via TNF receptor 1 in macrophages and dendritic cells M Zakharova, HK Ziegler The Journal of Immunology 175 (8), 5024-5033, 2005 | 186 | 2005 |
Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiency ML Bettini, F Pan, M Bettini, D Finkelstein, JE Rehg, S Floess, BD Bell, ... Immunity 36 (5), 717-730, 2012 | 181 | 2012 |
T cell islet accumulation in type 1 diabetes is a tightly regulated, cell-autonomous event GP Lennon, M Bettini, AR Burton, E Vincent, PY Arnold, P Santamaria, ... Immunity 31 (4), 643-653, 2009 | 175 | 2009 |
Prevention of autoimmune diabetes by ectopic pancreatic β-cell expression of interleukin-35 M Bettini, AH Castellaw, GP Lennon, AR Burton, DAA Vignali Diabetes 61 (6), 1519-1526, 2012 | 162 | 2012 |
LAG3 limits regulatory T cell proliferation and function in autoimmune diabetes Q Zhang, M Chikina, AL Szymczak-Workman, W Horne, JK Kolls, ... Science immunology 2 (9), eaah4569, 2017 | 159 | 2017 |
Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis MA Scavuzzo, MC Hill, J Chmielowiec, D Yang, J Teaw, K Sheng, Y Kong, ... Nature communications 9 (1), 3356, 2018 | 90 | 2018 |
A unique population: adipose-resident regulatory T cells Q Zeng, X Sun, L Xiao, Z Xie, M Bettini, T Deng Frontiers in immunology 9, 2075, 2018 | 71 | 2018 |
TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential M Bettini, L Blanchfield, A Castellaw, Q Zhang, M Nakayama, ... The Journal of Immunology 193 (2), 571-579, 2014 | 53 | 2014 |
Cutting edge: low-affinity TCRs support regulatory T cell function in autoimmunity ML Sprouse, I Shevchenko, MA Scavuzzo, F Joseph, T Lee, S Blum, ... The Journal of Immunology 200 (3), 909-914, 2018 | 52 | 2018 |
Generation of T cell receptor–retrogenic mice: improved retroviral-mediated stem cell gene transfer ML Bettini, M Bettini, M Nakayama, CS Guy, DAA Vignali Nature protocols 8 (10), 1837-1840, 2013 | 51 | 2013 |
Function, failure, and the future potential of Tregs in type 1 diabetes M Bettini, ML Bettini Diabetes 70 (6), 1211-1219, 2021 | 47 | 2021 |
Pathogenic MOG-reactive CD8+ T cells require MOG-reactive CD4+ T cells for sustained CNS inflammation during chronic EAE M Bettini, K Rosenthal, BD Evavold Journal of neuroimmunology 213 (1-2), 60-68, 2009 | 47 | 2009 |
High self-reactivity drives T-bet and potentiates Treg function in tissue-specific autoimmunity ML Sprouse, MA Scavuzzo, S Blum, I Shevchenko, T Lee, G Makedonas, ... Jci Insight 3 (2), 2018 | 42 | 2018 |
T‐cell receptor retrogenic mice: a rapid, flexible alternative to T‐cell receptor transgenic mice ML Bettini, M Bettini, DAA Vignali Immunology 136 (3), 265-272, 2012 | 39 | 2012 |
In vivo Treg suppression assays CJ Workman, LW Collison, M Bettini, MR Pillai, JE Rehg, DAA Vignali Regulatory T cells: Methods and Protocols, 119-156, 2011 | 37 | 2011 |
T cell-driven initiation and propagation of autoimmune diabetes M Bettini, DAA Vignali Current opinion in immunology 23 (6), 754-760, 2011 | 34 | 2011 |
Ectopic expression of self-antigen drives regulatory T cell development and not deletion of autoimmune T cells T Lee, ML Sprouse, P Banerjee, M Bettini, ML Bettini The Journal of Immunology 199 (7), 2270-2278, 2017 | 24 | 2017 |
A hybrid insulin epitope maintains high 2D affinity for diabetogenic T cells in the periphery B Liu, JD Hood, EM Kolawole, DM Woodruff, DA Vignali, M Bettini, ... Diabetes 69 (3), 381-391, 2020 | 21 | 2020 |