Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway CC Woo, SY Loo, V Gee, CW Yap, G Sethi, AP Kumar, KHB Tan Biochemical pharmacology 82 (5), 464-475, 2011 | 312 | 2011 |
γ‐Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro … P Rajendran, F Li, KA Manu, MK Shanmugam, SY Loo, AP Kumar, ... British journal of pharmacology 163 (2), 283-298, 2011 | 151 | 2011 |
microRNAs in breast cancer: regulatory roles governing the hallmarks of cancer JN Goh, SY Loo, A Datta, KS Siveen, WN Yap, W Cai, EM Shin, C Wang, ... Biological Reviews 91 (2), 409-428, 2016 | 124 | 2016 |
Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers F Li, MK Shanmugam, KS Siveen, F Wang, TH Ong, SY Loo, ... Oncotarget 6 (7), 5147, 2015 | 87 | 2015 |
NHE-1: a promising target for novel anti-cancer therapeutics S Yue Loo, M Ker Xing Chang, C Sui Huay Chua, A Prem Kumar, ... Current pharmaceutical design 18 (10), 1372-1382, 2012 | 86 | 2012 |
SPHK1 regulates proliferation and survival responses in triple-negative breast cancer A Datta, SY Loo, B Huang, L Wong, SSL Tan, TZ Tan, SC Lee, JP Thiery, ... Oncotarget 5 (15), 5920, 2014 | 84 | 2014 |
Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer SY Loo, LP Toh, WH Xie, E Pathak, W Tan, S Ma, MY Lee, ... Science advances 7 (41), eabh2443, 2021 | 64 | 2021 |
Computational identification and experimental validation of PPRE motifs in NHE1 and MnSOD genes of human G Venkatachalam, AP Kumar, LS Yue, S Pervaiz, MV Clement, ... BMC genomics 10, 1-13, 2009 | 57 | 2009 |
Manganese superoxide dismutase expression regulates the switch between an epithelial and a mesenchymal-like phenotype in breast carcinoma SY Loo, JL Hirpara, V Pandey, TZ Tan, CT Yap, PE Lobie, JP Thiery, ... Antioxidants & redox signaling 25 (6), 283-299, 2016 | 50 | 2016 |
An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell … A Subramaniam, SY Loo, P Rajendran, KA Manu, E Perumal, F Li, ... Apoptosis 18, 1175-1187, 2013 | 49 | 2013 |
Manganese superoxide dismutase is a promising target for enhancing chemosensitivity of basal-like breast carcinoma AP Kumar, SY Loo, SW Shin, TZ Tan, CB Eng, R Singh, TC Putti, CW Ong, ... Antioxidants & redox signaling 20 (15), 2326-2346, 2014 | 43 | 2014 |
Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma B Huang, S Deng, SY Loo, A Datta, YL Yap, B Yan, CH Ooi, TD Dinh, ... Oncotarget 7 (18), 25391, 2016 | 16 | 2016 |
Epigenetic derepression converts PPARγ into a druggable target in triple-negative and endocrine-resistant breast cancers SY Loo, NL Syn, APF Koh, JCF Teng, A Deivasigamani, TZ Tan, AA Thike, ... Cell Death Discovery 7 (1), 265, 2021 | 8 | 2021 |
Shifting the gears of metabolic plasticity to drive cell state transitions in cancer Z Wu, YF Lee, XH Yeo, SY Loo, WL Tam Cancers 13 (6), 1316, 2021 | 7 | 2021 |
DEAD-box RNA Helicases: The microRNA managers of breast cancer W Cai, C Wang, JN Goh, SY Loo, CT Yap, AP Kumar RNA & DISEASE 2, 2015 | 2 | 2015 |
Applying cellular thermal shift assays to uncover novel regulators of epithelial to mesenchymal transition in triple negative breast cancer JA Lidster, SY Loo, Z Wu, L Dai, SQ Ng, N Prabhu, D Kappei, WL Tam Cancer Research 84 (6_Supplement), 211-211, 2024 | | 2024 |
Methods for manipulating cell state transitions in cancer WL Tam, SY Loo, LP Toh US Patent App. 17/293,362, 2022 | | 2022 |
Shifting the Gears of Metabolic Plasticity to Drive Cell State Transitions in Cancer. Cancers 2021, 13, 1316 Z Wu, YF Lee, XH Yeo, SY Loo, WL Tam s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021 | | 2021 |
Epigenetic regulation of cell state transitions and the therapeutic implications in breast cancer LP Toh, SY Loo, WL Tam Cancer Research 80 (16_Supplement), 3833-3833, 2020 | | 2020 |
Abstract B22: Inducing cell state transitions in triple-negative breast cancer (TNBC) SY Loo, L Toh, E Pathak, W Tan, S Ma, J Yuan, G Periyasamy, F Torta, ... Molecular Cancer Research 16 (8_Supplement), B22-B22, 2018 | | 2018 |