Susan Klaeger
Susan Klaeger
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Tracking cancer drugs in living cells by thermal profiling of the proteome
MM Savitski, FBM Reinhard, H Franken, T Werner, MF Savitski, ...
Science 346 (6205), 1255784, 2014
The target landscape of clinical kinase drugs
S Klaeger, S Heinzlmeir, M Wilhelm, H Polzer, B Vick, PA Koenig, ...
Science 358 (6367), eaan4368, 2017
A large peptidome dataset improves HLA class I epitope prediction across most of the human population
S Sarkizova, S Klaeger, PM Le, LW Li, G Oliveira, H Keshishian, ...
Nature biotechnology 38 (2), 199-209, 2020
Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma
G Oliveira, K Stromhaug, S Klaeger, T Kula, DT Frederick, PM Le, ...
Nature 596 (7870), 119-125, 2021
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells
NR Mathew, F Baumgartner, L Braun, D O'Sullivan, S Thomas, ...
Nature medicine 24 (3), 282-291, 2018
DMSO enhances electrospray response, boosting sensitivity of proteomic experiments
H Hahne, F Pachl, B Ruprecht, SK Maier, S Klaeger, D Helm, G Médard, ...
Nature methods 10 (10), 989-991, 2013
Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity
GK Griffin, J Wu, A Iracheta-Vellve, JC Patti, J Hsu, T Davis, D Dele-Oni, ...
Nature 595 (7866), 309-314, 2021
Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer
T Ouspenskaia, T Law, KR Clauser, S Klaeger, S Sarkizova, F Aguet, B Li, ...
Nature biotechnology 40 (2), 209-217, 2022
Optimized chemical proteomics assay for kinase inhibitor profiling
G Médard, F Pachl, B Ruprecht, S Klaeger, S Heinzlmeir, D Helm, H Qiao, ...
Journal of proteome research 14 (3), 1574-1586, 2015
Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics
M Wilhelm, DP Zolg, M Graber, S Gessulat, T Schmidt, K Schnatbaum, ...
Nature communications 12 (1), 3346, 2021
Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs
S Weingarten-Gabbay, S Klaeger, S Sarkizova, LR Pearlman, DY Chen, ...
Cell 184 (15), 3962-3980. e17, 2021
Plant cytokinesis is orchestrated by the sequential action of the TRAPPII and exocyst tethering complexes
K Rybak, A Steiner, L Synek, S Klaeger, I Kulich, E Facher, G Wanner, ...
Developmental Cell 29 (5), 607-620, 2014
Chemical proteomics reveals ferrochelatase as a common off-target of kinase inhibitors
S Klaeger, B Gohlke, J Perrin, V Gupta, S Heinzlmeir, D Helm, H Qiao, ...
ACS chemical biology 11 (5), 1245-1254, 2016
Landscape of helper and regulatory antitumour CD4+ T cells in melanoma
G Oliveira, K Stromhaug, N Cieri, JB Iorgulescu, S Klaeger, JO Wolff, ...
Nature 605 (7910), 532-538, 2022
Chemical proteomics and structural biology define EPHA2 inhibition by clinical kinase drugs
S Heinzlmeir, D Kudlinzki, S Sreeramulu, S Klaeger, SL Gande, V Linhard, ...
ACS chemical biology 11 (12), 3400-3411, 2016
Optimized Plk1 PBD inhibitors based on poloxin induce mitotic arrest and apoptosis in tumor cells
A Scharow, M Raab, K Saxena, S Sreeramulu, D Kudlinzki, S Gande, ...
ACS chemical biology 10 (11), 2570-2579, 2015
Pharmacoproteomic characterisation of human colon and rectal cancer
M Frejno, R Zenezini Chiozzi, M Wilhelm, H Koch, R Zheng, S Klaeger, ...
Molecular systems biology 13 (11), 951, 2017
Optimized liquid and gas phase fractionation increases HLA-peptidome coverage for primary cell and tissue samples
S Klaeger, A Apffel, KR Clauser, S Sarkizova, G Oliveira, S Rachimi, ...
Molecular & Cellular Proteomics 20, 2021
Cell cycle‐regulated PLEIADE/At MAP 65‐3 links membrane and microtubule dynamics during plant cytokinesis
A Steiner, K Rybak, M Altmann, HE McFarlane, S Klaeger, N Nguyen, ...
The Plant Journal 88 (4), 531-541, 2016
Interactions between transport protein particle (TRAPP) complexes and Rab GTP ases in Arabidopsis
M Kalde, L Elliott, R Ravikumar, K Rybak, M Altmann, S Klaeger, C Wiese, ...
The Plant Journal 100 (2), 279-297, 2019
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