Markus Schirle
Markus Schirle
Novartis Institutes for BioMedical Research
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Cited by
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Proteome survey reveals modularity of the yeast cell machinery
AC Gavin, P Aloy, P Grandi, R Krause, M Boesche, M Marzioch, C Rau, ...
Nature 440 (7084), 631-636, 2006
Quantitative mass spectrometry in proteomics: a critical review
M Bantscheff, M Schirle, G Sweetman, J Rick, B Kuster
Analytical and bioanalytical chemistry 389, 1017-1031, 2007
Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
SMA Huang, YM Mishina, S Liu, A Cheung, F Stegmeier, GA Michaud, ...
Nature 461 (7264), 614-620, 2009
A physical and functional map of the human TNF-α/NF-κB signal transduction pathway
T Bouwmeester, A Bauch, H Ruffner, PO Angrand, G Bergamini, ...
Nature cell biology 6 (2), 97-105, 2004
Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide
ES Fischer, K Böhm, JR Lydeard, H Yang, MB Stadler, S Cavadini, ...
Nature 512 (7512), 49-53, 2014
Dermcidin: a novel human antibiotic peptide secreted by sweat glands
B Schittek, R Hipfel, B Sauer, J Bauer, H Kalbacher, S Stevanovic, ...
Nature immunology 2 (12), 1133-1137, 2001
Computational prediction of proteotypic peptides for quantitative proteomics
P Mallick, M Schirle, SS Chen, MR Flory, H Lee, D Martin, J Ranish, ...
Nature biotechnology 25 (1), 125-131, 2007
The HLA-A* 6601 peptide motif: prediction by pocket structure and verification by peptide analysis
FH Seeger, M Schirle, J Gatfield, D Arnold, W Keilholz, P Nickolaus, ...
Immunogenetics 49, 571-576, 1999
Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
WE Dowdle, B Nyfeler, J Nagel, RA Elling, S Liu, E Triantafellow, ...
Nature cell biology 16 (11), 1069-1079, 2014
Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products
REM Toes, AK Nussbaum, S Degermann, M Schirle, NPN Emmerich, ...
The Journal of experimental medicine 194 (1), 1-12, 2001
Cleavage motifs of the yeast 20S proteasome β subunits deduced from digests of enolase 1
AK Nussbaum, TP Dick, W Keilholz, M Schirle, S Stevanović, K Dietz, ...
Proceedings of the National Academy of Sciences 95 (21), 12504-12509, 1998
Scoring proteomes with proteotypic peptide probes
B Kuster, M Schirle, P Mallick, R Aebersold
Nature reviews Molecular cell biology 6 (7), 577-583, 2005
RNF146 is a poly (ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling
Y Zhang, S Liu, C Mickanin, Y Feng, O Charlat, GA Michaud, M Schirle, ...
Nature cell biology 13 (5), 623-629, 2011
Contribution of proteasomal β-subunits to the cleavage of peptide substrates analyzed with yeast mutants
TP Dick, AK Nussbaum, M Deeg, W Heinemeyer, M Groll, M Schirle, ...
Journal of Biological Chemistry 273 (40), 25637-25646, 1998
Integrated functional genomics approach for the design of patient-individual antitumor vaccines
T Weinschenk, C Gouttefangeas, M Schirle, F Obermayr, S Walter, ...
Cancer research 62 (20), 5818-5827, 2002
Two new proteases in the MHC class I processing pathway
L Stoltze, M Schirle, G Schwarz, C Schröter, MW Thompson, LB Hersh, ...
Nature immunology 1 (5), 413-418, 2000
Harnessing the anti-cancer natural product nimbolide for targeted protein degradation
JN Spradlin, X Hu, CC Ward, SM Brittain, MD Jones, L Ou, M To, ...
Nature chemical biology 15 (7), 747-755, 2019
Bone overgrowth-associated mutations in the LRP4 gene impair sclerostin facilitator function
O Leupin, E Piters, C Halleux, S Hu, I Kramer, F Morvan, T Bouwmeester, ...
Journal of Biological Chemistry 286 (22), 19489-19500, 2011
Bartonella Adhesin A Mediates a Proangiogenic Host Cell Response
T Riess, SGE Andersson, A Lupas, M Schaller, A Schäfer, P Kyme, ...
The Journal of experimental medicine 200 (10), 1267-1278, 2004
Profiling Core Proteomes of Human Cell Lines by One-dimensional PAGE and Liquid Chromatography-Tandem Mass Spectrometry* S
M Schirle, MA Heurtier, B Kuster
Molecular & Cellular Proteomics 2 (12), 1297-1305, 2003
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