| Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients G Schwank, BK Koo, V Sasselli, JF Dekkers, I Heo, T Demircan, N Sasaki, ... Cell stem cell 13 (6), 653-658, 2013 | 1506 | 2013 |
| Sequential cancer mutations in cultured human intestinal stem cells J Drost, RH Van Jaarsveld, B Ponsioen, C Zimberlin, R Van Boxtel, ... Nature 521 (7550), 43-47, 2015 | 964 | 2015 |
| Tissue-specific mutation accumulation in human adult stem cells during life F Blokzijl, J De Ligt, M Jager, V Sasselli, S Roerink, N Sasaki, M Huch, ... Nature 538 (7624), 260-264, 2016 | 810 | 2016 |
| Auxin triggers transient local signaling for cell specification in Arabidopsis embryogenesis D Weijers, A Schlereth, JS Ehrismann, G Schwank, M Kientz, G Jürgens Developmental cell 10 (2), 265-270, 2006 | 372 | 2006 |
| Treatment of a metabolic liver disease by in vivo genome base editing in adult mice L Villiger, HM Grisch-Chan, H Lindsay, F Ringnalda, CB Pogliano, ... Nature medicine 24 (10), 1519-1525, 2018 | 337 | 2018 |
| Organoid models of human liver cancers derived from tumor needle biopsies S Nuciforo, I Fofana, MS Matter, T Blumer, D Calabrese, T Boldanova, ... Cell reports 24 (5), 1363-1376, 2018 | 316 | 2018 |
| Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell–derived IFN-γ HF Farin, WR Karthaus, P Kujala, M Rakhshandehroo, G Schwank, ... Journal of Experimental Medicine 211 (7), 1393-1405, 2014 | 264 | 2014 |
| Advances in therapeutic CRISPR/Cas9 genome editing N Savić, G Schwank Translational Research 168, 15-21, 2016 | 261 | 2016 |
| High-throughput automated organoid culture via stem-cell aggregation in microcavity arrays N Brandenberg, S Hoehnel, F Kuttler, K Homicsko, C Ceroni, T Ringel, ... Nature biomedical engineering 4 (9), 863-874, 2020 | 213 | 2020 |
| Growth of epithelial organoids in a defined hydrogel N Broguiere, L Isenmann, C Hirt, T Ringel, S Placzek, E Cavalli, ... Advanced Materials 30 (43), 1801621, 2018 | 186 | 2018 |
| In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels T Rothgangl, MK Dennis, PJC Lin, R Oka, D Witzigmann, L Villiger, W Qi, ... Nature biotechnology 39 (8), 949-957, 2021 | 173 | 2021 |
| Regulation of organ growth by morphogen gradients G Schwank, K Basler Cold Spring Harbor perspectives in biology 2 (1), a001669, 2010 | 153 | 2010 |
| Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair N Savic, FCAS Ringnalda, H Lindsay, C Berk, K Bargsten, Y Li, D Neri, ... elife 7, e33761, 2018 | 149 | 2018 |
| Growth regulation by Dpp: an essential role for Brinker and a non-essential role for graded signaling levels G Schwank, S Restrepo, K Basler Oxford University Press for The Company of Biologists Limited 135 (24), 4003 …, 2008 | 131 | 2008 |
| Genome-scale CRISPR screening in human intestinal organoids identifies drivers of TGF-β resistance T Ringel, N Frey, F Ringnalda, S Janjuha, S Cherkaoui, S Butz, S Srivatsa, ... Cell stem cell 26 (3), 431-440. e8, 2020 | 105 | 2020 |
| Formation of the long range Dpp morphogen gradient G Schwank, S Dalessi, SF Yang, R Yagi, AM de Lachapelle, M Affolter, ... PLoS biology 9 (7), e1001111, 2011 | 95 | 2011 |
| Generation of BAC transgenic epithelial organoids G Schwank, A Andersson-Rolf, BK Koo, N Sasaki, H Clevers PloS one 8 (10), e76871, 2013 | 83 | 2013 |
| Antagonistic growth regulation by Dpp and Fat drives uniform cell proliferation G Schwank, G Tauriello, R Yagi, E Kranz, P Koumoutsakos, K Basler Developmental cell 20 (1), 123-130, 2011 | 78 | 2011 |
| In vivo prime editing of a metabolic liver disease in mice D Böck, T Rothgangl, L Villiger, L Schmidheini, M Matsushita, N Mathis, ... Science translational medicine 14 (636), eabl9238, 2022 | 57 | 2022 |
| Comment on "Dynamics of dpp signaling and proliferation control" G Schwank, SF Yang, S Restrepo, K Basler Science 335 (6067), 401, 2012 | 55* | 2012 |
Hans CleversHubrecht Institute - UtrechtVerified email at hubrecht.eu
