|Transcription factor achaete scute-like 2 controls intestinal stem cell fate|
LG van der Flier, ME van Gijn, P Hatzis, P Kujala, A Haegebarth, ...
Cell 136 (5), 903-912, 2009
|Wnt signalling induces maturation of Paneth cells in intestinal crypts|
JH van Es, P Jay, A Gregorieff, ME van Gijn, S Jonkheer, P Hatzis, ...
Nature cell biology 7 (4), 381-386, 2005
|Plasticity and expanding complexity of the hepatic transcription factor network during liver development|
I Kyrmizi, P Hatzis, N Katrakili, F Tronche, FJ Gonzalez, I Talianidis
Genes & development 20 (16), 2293-2305, 2006
|Dynamics of enhancer-promoter communication during differentiation-induced gene activation|
P Hatzis, I Talianidis
Molecular cell 10 (6), 1467-1477, 2002
|Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells|
P Hatzis, LG van der Flier, MA van Driel, V Guryev, F Nielsen, S Denissov, ...
Molecular and cellular biology, 2008
|Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts|
J Schuijers, JP Junker, M Mokry, P Hatzis, BK Koo, V Sasselli, ...
Cell stem cell 16 (2), 158-170, 2015
|Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand|
SF Boj, JH van Es, M Huch, VSW Li, A José, P Hatzis, M Mokry, ...
Cell 151 (7), 1595-1607, 2012
|Wnt‐induced transcriptional activation is exclusively mediated by TCF/LEF|
J Schuijers, M Mokry, P Hatzis, E Cuppen, H Clevers
The EMBO journal 33 (2), 146-156, 2014
|Regulatory mechanisms controlling human hepatocyte nuclear factor 4α gene expression|
P Hatzis, I Talianidis
Molecular and cellular biology 21 (21), 7320-7330, 2001
|The intracellular localization of deoxycytidine kinase|
P Hatzis, AS Al-Madhoon, M Jullig, TG Petrakis, S Eriksson, I Talianidis
Journal of Biological Chemistry 273 (46), 30239-30243, 1998
|Selection of personalized patient therapy through the use of knowledge-based computational models that identify tumor-driving signal transduction pathways|
W Verhaegh, H van Ooijen, MA Inda, P Hatzis, R Versteeg, M Smid, ...
Cancer research 74 (11), 2936-2945, 2014
|The Tup1-Cyc8 protein complex can shift from a transcriptional co-repressor to a transcriptional co-activator|
RS Conlan, N Gounalaki, P Hatzis, D Tzamarias
Journal of Biological Chemistry 274 (1), 205-210, 1999
|Systematic integration of RNA-Seq statistical algorithms for accurate detection of differential gene expression patterns|
P Moulos, P Hatzis
Nucleic acids research 43 (4), e25-e25, 2015
|Cooperative Synergy between NFAT and MyoD Regulates Myogenin Expression and Myogenesis∗|
AS Armand, M Bourajjaj, S Martínez-Martínez, H el Azzouzi, ...
Journal of Biological Chemistry 283 (43), 29004-29010, 2008
|The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis|
T Mahmoudi, SF Boj, P Hatzis, VSW Li, N Taouatas, RGJ Vries, ...
PLoS biology 8 (11), e1000539, 2010
|TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions|
MP Verzi, P Hatzis, R Sulahian, J Philips, J Schuijers, H Shin, E Freed, ...
Proceedings of the National Academy of Sciences 107 (34), 15157-15162, 2010
|Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes|
M Mokry, P Hatzis, J Schuijers, N Lansu, FP Ruzius, H Clevers, E Cuppen
Nucleic acids research 40 (1), 148-158, 2012
|The E3 ligase RNF43 inhibits Wnt signaling downstream of mutated β-catenin by sequestering TCF4 to the nuclear membrane|
A Loregger, M Grandl, R Mejías-Luque, M Allgäuer, K Degenhart, ...
Science signaling 8 (393), ra90-ra90, 2015
|Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma|
E De Crignis, T Hossain, S Romal, F Carofiglio, P Moulos, MM Khalid, ...
Elife 10, e60747, 2021
|Mitogen-activated protein kinase-mediated disruption of enhancer-promoter communication inhibits hepatocyte nuclear factor 4α expression|
P Hatzis, I Kyrmizi, I Talianidis
Molecular and cellular biology 26 (19), 7017-7029, 2006