Molecular diversity of midbrain development in mouse, human, and stem cells G La Manno, D Gyllborg, S Codeluppi, K Nishimura, C Salto, A Zeisel, ... Cell 167 (2), 566-580. e19, 2016 | 828 | 2016 |
Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease EM Toledo, NC Inestrosa Molecular psychiatry 15 (3), 272-285, 2010 | 358 | 2010 |
Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model P Rivetti Di Val Cervo, RA Romanov, G Spigolon, D Masini, ... Nature biotechnology 35 (5), 444-452, 2017 | 324 | 2017 |
Wnt signaling in neuroprotection and stem cell differentiation EM Toledo, M Colombres, NC Inestrosa Progress in neurobiology 86 (3), 281-296, 2008 | 291 | 2008 |
The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease NC Inestrosa, EM Toledo Molecular neurodegeneration 3, 1-13, 2008 | 231 | 2008 |
STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's β-amyloid deposits GI Cancino, EM Toledo, NR Leal, DE Hernandez, LF Yévenes, ... Brain 131 (9), 2425-2442, 2008 | 174 | 2008 |
Wnt-7a induces presynaptic colocalization of α7-nicotinic acetylcholine receptors and adenomatous polyposis coli in hippocampal neurons GG Farías, AS Vallés, M Colombres, JA Godoy, EM Toledo, RJ Lukas, ... Journal of Neuroscience 27 (20), 5313-5325, 2007 | 147 | 2007 |
Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis S Theofilopoulos, Y Wang, SS Kitambi, P Sacchetti, KM Sousa, K Bodin, ... Nature chemical biology 9 (2), 126-133, 2013 | 139 | 2013 |
c-Abl tyrosine kinase modulates tau pathology and Cdk5 phosphorylation in AD transgenic mice GI Cancino, KP de Arce, PU Castro, EM Toledo, R von Bernhardi, ... Neurobiology of aging 32 (7), 1249-1261, 2011 | 131 | 2011 |
Anti–ribosomal P protein autoantibodies from patients with neuropsychiatric lupus impair memory in mice M Bravo‐Zehnder, EM Toledo, F Segovia‐Miranda, FG Serrano, ... Arthritis & rheumatology 67 (1), 204-214, 2015 | 122 | 2015 |
A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease JC Villaescusa, B Li, EM Toledo, PIA Rivetti di Val Cervo, S Yang, ... The EMBO journal 35 (18), 1963-1978, 2016 | 105 | 2016 |
Calcium/calmodulin‐dependent protein kinase type IV is a target gene of the Wnt/β‐catenin signaling pathway MS Arrázola, L Varela‐Nallar, M Colombres, EM Toledo, F Cruzat, ... Journal of cellular physiology 221 (3), 658-667, 2009 | 96 | 2009 |
Induction of cellular prion protein gene expression by copper in neurons L Varela-Nallar, EM Toledo, LF Larrondo, ALB Cabral, VR Martins, ... American Journal of Physiology-Cell Physiology 290 (1), C271-C281, 2006 | 92 | 2006 |
Peroxisome proliferators reduce spatial memory impairment, synaptic failure, and neurodegeneration in brains of a double transgenic mice model of Alzheimer's disease NC Inestrosa, FJ Carvajal, JM Zolezzi, C Tapia-Rojas, F Serrano, ... Journal of Alzheimer's Disease 33 (4), 941-959, 2013 | 76 | 2013 |
SFRP1 and SFRP2 dose‐dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells J Kele, ER Andersson, JC Villaescusa, L Cajanek, CL Parish, S Bonilla, ... Stem cells 30 (5), 865-875, 2012 | 76 | 2012 |
The role of Wnt signaling in neuroprotection. W Cerpa, EM Toledo, L Varela-Nallar, NC Inestrosa Drug news & perspectives 22 (10), 579-591, 2009 | 71 | 2009 |
Niche-derived laminin-511 promotes midbrain dopaminergic neuron survival and differentiation through YAP D Zhang, S Yang, EM Toledo, D Gyllborg, C Saltó, J Carlos Villaescusa, ... Science signaling 10 (493), eaal4165, 2017 | 66 | 2017 |
Release of acetylcholinesterase (AChE) from β-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice MC Dinamarca, M Arrázola, E Toledo, WF Cerpa, J Hancke, NC Inestrosa Chemico-biological interactions 175 (1-3), 142-149, 2008 | 60 | 2008 |
The matricellular protein R-spondin 2 promotes midbrain dopaminergic neurogenesis and differentiation D Gyllborg, M Ahmed, EM Toledo, S Theofilopoulos, S Yang, E Arenas Stem Cell Reports 11 (3), 651-664, 2018 | 30 | 2018 |
Srebf1 controls midbrain dopaminergic neurogenesis EM Toledo, S Yang, D Gyllborg, KE van Wijk, I Sinha, M Varas-Godoy, ... Cell Reports 31 (5), 2020 | 28 | 2020 |