| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 13555* | 2021 |
| Coupling endoplasmic reticulum stress to the cell death program RV Rao, HM Ellerby, DE Bredesen Cell Death & Differentiation 11 (4), 372-380, 2004 | 2435* | 2004 |
| Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species DJ Kane, TA Sarafian, R Anton, H Hahn, EB Gralla, JS Valentine, T Örd, ... Science 262 (5137), 1274-1277, 1993 | 2119 | 1993 |
| Bax directly induces release of cytochrome c from isolated mitochondria JM Jürgensmeier, Z Xie, Q Deveraux, L Ellerby, D Bredesen, JC Reed Proceedings of the National Academy of Sciences 95 (9), 4997-5002, 1998 | 2098 | 1998 |
| Neurological manifestations of the acquired immunodeficiency syndrome (AIDS): experience at UCSF and review of the literature RM Levy, DE Bredesen, ML Rosenblum Journal of neurosurgery 62 (4), 475-495, 1985 | 1567 | 1985 |
| An alternative, nonapoptotic form of programmed cell death S Sperandio, I de Belle, DE Bredesen Proceedings of the National Academy of Sciences 97 (26), 14376-14381, 2000 | 1253 | 2000 |
| Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 L Galluzzi, BS Pedro, I Vitale, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 22 (1), 58-73, 2015 | 1191 | 2015 |
| Anti-cancer activity of targeted pro-apoptotic peptides HM Ellerby, W Arap, LM Ellerby, R Kain, R Andrusiak, GD Rio, ... Nature medicine 5 (9), 1032-1038, 1999 | 1184 | 1999 |
| Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-β levels in a mouse model of Alzheimer's disease P Spilman, N Podlutskaya, MJ Hart, J Debnath, O Gorostiza, D Bredesen, ... PloS one 5 (4), e9979, 2010 | 1169 | 2010 |
| Induction of apoptosis by the low-affinity NGF receptor S Rabizadeh, J Oh, L Zhong, J Yang, CM Bitler, LL Butcher, DE Bredesen Science 261 (5119), 345-348, 1993 | 1051 | 1993 |
| Pro-caspase-3 is a major physiologic target of caspase-8 HR Stennicke, JM Jurgensmeier, H Shin, Q Deveraux, BB Wolf, X Yang, ... Journal of Biological Chemistry 273 (42), 27084-27090, 1998 | 1028 | 1998 |
| Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis M Wiedau-Pazos, JJ Goto, S Rabizadeh, EB Gralla, JA Roe, MK Lee, ... Science 271 (5248), 515-518, 1996 | 947 | 1996 |
| Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis I Kruman, AJ Bruce-Keller, D Bredesen, G Waeg, MP Mattson Journal of Neuroscience 17 (13), 5089-5100, 1997 | 939 | 1997 |
| Cell death in the nervous system DE Bredesen, RV Rao, P Mehlen Nature 443 (7113), 796-802, 2006 | 893 | 2006 |
| Lysosomal protease pathways to apoptosis: cleavage of Bid, not pro-caspases, is the most likely route V Stoka, B Turk, SL Schendel, TH Kim, T Cirman, SJ Snipas, LM Ellerby, ... Journal of Biological Chemistry 276 (5), 3149-3157, 2001 | 875 | 2001 |
| Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes L Galluzzi, SA Aaronson, J Abrams, ES Alnemri, DW Andrews, ... Cell Death & Differentiation 16 (8), 1093-1107, 2009 | 857 | 2009 |
| bcl-2 inhibits death of central neural cells induced by multiple agents. L Zhong, T Sarafian, DJ Kane, AC Charles, SP Mah, RH Edwards, ... Proceedings of the National Academy of Sciences 90 (10), 4533-4537, 1993 | 834 | 1993 |
| Neural apoptosis DE Bredesen Annals of neurology 38 (6), 839-851, 1995 | 769 | 1995 |
| Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78 RV Rao, A Peel, A Logvinova, G del Rio, E Hermel, T Yokota, ... FEBS letters 514 (2-3), 122-128, 2002 | 734 | 2002 |
| Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract CL Wellington, LM Ellerby, AS Hackam, RL Margolis, MA Trifiro, ... Journal of Biological Chemistry 273 (15), 9158-9167, 1998 | 734 | 1998 |
