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Chao Zhang
Chao Zhang
Professor of Chemistry, University of Southern California
Verified email at usc.edu
Title
Cited by
Cited by
Year
RAF inhibitors transactivate RAF dimers and ERK signalling in cells with wild-type BRAF
PI Poulikakos, C Zhang, G Bollag, KM Shokat, N Rosen
Nature 464 (7287), 427-430, 2010
20192010
IRE1 signaling affects cell fate during the unfolded protein response
JH Lin, H Li, D Yasumura, HR Cohen, C Zhang, B Panning, KM Shokat, ...
science 318 (5852), 944-949, 2007
15992007
The unfolded protein response signals through high-order assembly of Ire1
AV Korennykh, PF Egea, AA Korostelev, J Finer-Moore, C Zhang, ...
Nature 457 (7230), 687-693, 2009
7682009
Structural bioinformatics-based design of selective, irreversible kinase inhibitors
MS Cohen, C Zhang, KM Shokat, J Taunton
Science 308 (5726), 1318-1321, 2005
7212005
Single-cell landscape of immunological responses in patients with COVID-19
JY Zhang, XM Wang, X Xing, Z Xu, C Zhang, JW Song, X Fan, P Xia, ...
Nature immunology 21 (9), 1107-1118, 2020
5502020
The advantages of targeted protein degradation over inhibition: an RTK case study
GM Burslem, BE Smith, AC Lai, S Jaime-Figueroa, DC McQuaid, ...
Cell chemical biology 25 (1), 67-77. e3, 2018
5392018
Discovery of nitrate–CPK–NLP signalling in central nutrient–growth networks
K Liu, Y Niu, M Konishi, Y Wu, H Du, H Sun Chung, L Li, M Boudsocq, ...
Nature 545 (7654), 311-316, 2017
4752017
Chemical genetic analysis of the time course of signal transduction by JNK
JJ Ventura, A Hübner, C Zhang, RA Flavell, KM Shokat, RJ Davis
Molecular cell 21 (5), 701-710, 2006
4172006
Immunological and inflammatory profiles in mild and severe cases of COVID-19
JW Song, C Zhang, X Fan, FP Meng, Z Xu, P Xia, WJ Cao, T Yang, XP Dai, ...
Nature communications 11 (1), 3410, 2020
3922020
TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II
K Glover-Cutter, S Larochelle, B Erickson, C Zhang, K Shokat, RP Fisher, ...
Molecular and cellular biology 29 (20), 5455-5464, 2009
3822009
Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II
S Larochelle, R Amat, K Glover-Cutter, M Sansó, C Zhang, JJ Allen, ...
Nature structural & molecular biology 19 (11), 1108-1115, 2012
3812012
Phosphoproteomic analysis reveals interconnected system-wide responses to perturbations of kinases and phosphatases in yeast
B Bodenmiller, S Wanka, C Kraft, J Urban, D Campbell, PG Pedrioli, ...
Science signaling 3 (153), rs4-rs4, 2010
3722010
Calcium-dependent protein kinase 1 is an essential regulator of exocytosis in Toxoplasma
S Lourido, J Shuman, C Zhang, KM Shokat, R Hui, LD Sibley
Nature 465 (7296), 359-362, 2010
3662010
Control of landmark events in meiosis by the CDK Cdc28 and the meiosis-specific kinase Ime2
KR Benjamin, C Zhang, KM Shokat, I Herskowitz
Genes & development 17 (12), 1524-1539, 2003
3442003
Inhibitor hijacking of Akt activation
T Okuzumi, D Fiedler, C Zhang, DC Gray, B Aizenstein, R Hoffman, ...
Nature chemical biology 5 (7), 484-493, 2009
3322009
An unbiased cell morphology–based screen for new, biologically active small molecules
M Tanaka, R Bateman, D Rauh, E Vaisberg, S Ramachandani, C Zhang, ...
PLoS biology 3 (5), e128, 2005
3142005
Bypassing a kinase activity with an ATP-competitive drug
FR Papa, C Zhang, K Shokat, P Walter
Science 302 (5650), 1533-1537, 2003
3082003
Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells
ME Burkard, CL Randall, S Larochelle, C Zhang, KM Shokat, RP Fisher, ...
Proceedings of the National Academy of Sciences 104 (11), 4383-4388, 2007
3062007
An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED
W Qi, K Zhao, J Gu, Y Huang, Y Wang, H Zhang, M Zhang, J Zhang, Z Yu, ...
Nature chemical biology 13 (4), 381-388, 2017
2952017
Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells
S Larochelle, KA Merrick, ME Terret, L Wohlbold, NM Barboza, C Zhang, ...
Molecular cell 25 (6), 839-850, 2007
2742007
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