CD36 is a sensor of diacylglycerides K Hoebe, P Georgel, S Rutschmann, X Du, S Mudd, K Crozat, S Sovath, ... Nature 433 (7025), 523-527, 2005 | 1088 | 2005 |
Toll-like receptor 2 suppresses immunity against Candida albicans through induction of IL-10 and regulatory T cells MG Netea, R Sutmuller, C Hermann, CAA Van der Graaf, ... The Journal of Immunology 172 (6), 3712-3718, 2004 | 823 | 2004 |
Lipoteichoic acid (LTA) of Streptococcus pneumoniaeand Staphylococcus aureus activates immune cells via Toll-like receptor (TLR)-2, lipopolysaccharide-binding protein (LBP … NWJ Schröder, S Morath, C Alexander, L Hamann, T Hartung, ... Journal of biological chemistry 278 (18), 15587-15594, 2003 | 807 | 2003 |
Innate immunity in Arabidopsis thaliana: lipopolysaccharides activate nitric oxide synthase (NOS) and induce defense genes D Zeidler, U Zähringer, I Gerber, I Dubery, T Hartung, W Bors, P Hutzler, ... Proceedings of the National Academy of Sciences 101 (44), 15811-15816, 2004 | 771 | 2004 |
Toxicology for the twenty-first century T Hartung Nature 460 (7252), 208-212, 2009 | 669 | 2009 |
Structure–Function Relationship of Cytokine Induction by Lipoteichoic Acid fromStaphylococcus aureus S Morath, A Geyer, T Hartung The Journal of experimental medicine 193 (3), 393-398, 2001 | 599 | 2001 |
Membrane sorting of toll-like receptor (TLR)-2/6 and TLR2/1 heterodimers at the cell surface determines heterotypic associations with CD36 and intracellular targeting M Triantafilou, FGJ Gamper, RM Haston, MA Mouratis, S Morath, ... Journal of Biological Chemistry 281 (41), 31002-31011, 2006 | 584 | 2006 |
Multi-tissue interactions in an integrated three-tissue organ-on-a-chip platform A Skardal, SV Murphy, M Devarasetty, I Mead, HW Kang, YJ Seol, ... Scientific reports 7 (1), 8837, 2017 | 565 | 2017 |
Enhanced antiinflammatory capacity of a Lactobacillus plantarum mutant synthesizing modified teichoic acids C Grangette, S Nutten, E Palumbo, S Morath, C Hermann, J Dewulf, B Pot, ... Proceedings of the National Academy of Sciences 102 (29), 10321-10326, 2005 | 544 | 2005 |
Prevalence of Borrelia burgdorferi Sensu Lato Genospecies in Ixodes ricinus Ticks in Europe: a Metaanalysis C Rauter, T Hartung Applied and environmental microbiology 71 (11), 7203-7216, 2005 | 499 | 2005 |
Guidance on good cell culture practice: a report of the second ECVAM task force on good cell culture practice S Coecke, M Balls, G Bowe, J Davis, G Gstraunthaler, T Hartung, R Hay, ... Alternatives to Laboratory Animals 33 (3), 261-287, 2005 | 484 | 2005 |
Interleukin-10 counterregulates proinflammatory cytokine-induced inhibition of neutrophil apoptosis during severe sepsis M Keel, U Ungethüm, U Steckholzer, E Niederer, T Hartung, O Trentz, ... Blood, The Journal of the American Society of Hematology 90 (9), 3356-3363, 1997 | 406 | 1997 |
The role of toll-like receptors (TLRs) in bacteria-induced maturation of murine dendritic cells (DCS): peptidoglycan and lipoteichoic acid are inducers of DC maturation and … KS Michelsen, A Aicher, M Mohaupt, T Hartung, S Dimmeler, ... Journal of Biological Chemistry 276 (28), 25680-25686, 2001 | 396 | 2001 |
A modular approach to the ECVAM principles on test validity T Hartung, S Bremer, S Casati, S Coecke, R Corvi, S Fortaner, L Gribaldo, ... Alternatives to Laboratory Animals 32 (5), 467-472, 2004 | 386 | 2004 |
Lipopolysaccharide and ceramide docking to CD14 provokes ligand‐specific receptor clustering in rafts A Pfeiffer, A Böttcher, E Orsó, M Kapinsky, P Nagy, A Bodnár, I Spreitzer, ... European journal of immunology 31 (11), 3153-3164, 2001 | 384 | 2001 |
Induction of cross-tolerance by lipopolysaccharide and highly purified lipoteichoic acid via different Toll-like receptors independent of paracrine mediators MD Lehner, S Morath, KS Michelsen, RR Schumann, T Hartung The Journal of Immunology 166 (8), 5161-5167, 2001 | 384 | 2001 |
Applying adverse outcome pathways (AOPs) to support integrated approaches to testing and assessment (IATA) KE Tollefsen, S Scholz, MT Cronin, SW Edwards, J de Knecht, K Crofton, ... Regulatory Toxicology and Pharmacology 70 (3), 629-640, 2014 | 368 | 2014 |
Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of Toxicology 91, 3477-3505, 2017 | 364 | 2017 |
L-ficolin specifically binds to lipoteichoic acid, a cell wall constituent of Gram-positive bacteria, and activates the lectin pathway of complement NJ Lynch, S Roscher, T Hartung, S Morath, M Matsushita, DN Maennel, ... The Journal of Immunology 172 (2), 1198-1202, 2004 | 356 | 2004 |
Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing U Marx, TB Andersson, A Bahinski, M Beilmann, S Beken, FR Cassee, ... Altex 33 (3), 272, 2016 | 354 | 2016 |