Gary Ruvkun
Gary Ruvkun
Professor of Genetics, Harvard Medical School
Verified email at - Homepage
Cited by
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The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
BJ Reinhart, FJ Slack, M Basson, AE Pasquinelli, JC Bettinger, ...
nature 403 (6772), 901-906, 2000
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
B Wightman, I Ha, G Ruvkun
Cell 75 (5), 855-862, 1993
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
AE Pasquinelli, BJ Reinhart, F Slack, MQ Martindale, MI Kuroda, B Maller, ...
Nature 408 (6808), 86-89, 2000
daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
KD Kimura, HA Tissenbaum, Y Liu, G Ruvkun
Science 277 (5328), 942-946, 1997
Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing
A Grishok, AE Pasquinelli, D Conte, N Li, S Parrish, I Ha, DL Baillie, A Fire, ...
Cell 106 (1), 23-34, 2001
A uniform system for microRNA annotation
V Ambros, B Bartel, DP Bartel, CB Burge, JC Carrington, X Chen, ...
Rna 9 (3), 277-279, 2003
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
S Ogg, S Paradis, S Gottlieb, GI Patterson, L Lee, HA Tissenbaum, ...
Nature 389 (6654), 994-999, 1997
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
K Ashrafi, FY Chang, JL Watts, AG Fraser, RS Kamath, J Ahringer, ...
Nature 421 (6920), 268-272, 2003
Physical and genetic characterization of symbiotic and auxotrophic mutants of Rhizobium meliloti induced by transposon Tn5 mutagenesis
HM Meade, SR Long, GB Ruvkun, SE Brown, FM Ausubel
Journal of bacteriology 149 (1), 114-122, 1982
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
JZ Morris, HA Tissenbaum, G Ruvkun
Nature 382 (6591), 536-539, 1996
A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity
SS Lee, RYN Lee, AG Fraser, RS Kamath, J Ahringer, G Ruvkun
Nature genetics 33 (1), 40-48, 2003
The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor
FJ Slack, M Basson, Z Liu, V Ambros, HR Horvitz, G Ruvkun
Molecular cell 5 (4), 659-669, 2000
The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products
W Herr, RA Sturm, RG Clerc, LM Corcoran, D Baltimore, PA Sharp, ...
Genes Dev 2 (12A), 1513-6, 1988
Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor
S Paradis, G Ruvkun
Genes & development 12 (16), 2488-2498, 1998
Regulation of C. elegans life-span by insulinlike signaling in the nervous system
CA Wolkow, KD Kimura, MS Lee, G Ruvkun
Science 290 (5489), 147-150, 2000
A general method for site-directed mutagenesis in prokaryotes
GB Ruvkun, FM Ausubel
Nature 289 (5793), 85-88, 1981
DAF-16 target genes that control C. elegans life-span and metabolism
SS Lee, S Kennedy, AC Tolonen, G Ruvkun
science 300 (5619), 644-647, 2003
Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
J Kim, A Krichevsky, Y Grad, GD Hayes, KS Kosik, GM Church, G Ruvkun
Proceedings of the National Academy of Sciences 101 (1), 360-365, 2004
Regulation of DAF-2 receptor signaling by human insulin and ins-1, a member of the unusually large and diverse C. elegans insulin gene family
SB Pierce, M Costa, R Wisotzkey, S Devadhar, SA Homburger, ...
Genes & development 15 (6), 672-686, 2001
A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans
S Kennedy, D Wang, G Ruvkun
Nature 427 (6975), 645-649, 2004
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