Eefjan Breukink
Cited by
Cited by
Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic
E Breukink, I Wiedemann, C Kraaij, OP Kuipers, HG Sahl, B De Kruijff
Science 286 (5448), 2361-2364, 1999
Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity
I Wiedemann, E Breukink, C Van Kraaij, OP Kuipers, G Bierbaum, ...
Journal of Biological Chemistry 276 (3), 1772-1779, 2001
Lipid II as a target for antibiotics
E Breukink, B de Kruijff
Nature reviews Drug discovery 5 (4), 321-323, 2006
The nisin–lipid II complex reveals a pyrophosphate cage that provides a blueprint for novel antibiotics
STD Hsu, E Breukink, E Tischenko, MAG Lutters, B De Kruijff, R Kaptein, ...
Nature structural & molecular biology 11 (10), 963-967, 2004
An alternative bactericidal mechanism of action for lantibiotic peptides that target lipid II
HE Hasper, NE Kramer, JL Smith, JD Hillman, C Zachariah, OP Kuipers, ...
Science 313 (5793), 1636-1637, 2006
Identification of FtsW as a transporter of lipid‐linked cell wall precursors across the membrane
T Mohammadi, V Van Dam, R Sijbrandi, T Vernet, A Zapun, A Bouhss, ...
The EMBO journal 30 (8), 1425-1432, 2011
The lantibiotic nisin, a special case or not?
E Breukink, B de Kruijff
Biochimica et Biophysica Acta (BBA)-Biomembranes 1462 (1-2), 223-234, 1999
Lipid II is an intrinsic component of the pore induced by nisin in bacterial membranes
E Breukink, HE van Heusden, PJ Vollmerhaus, E Swiezewska, L Brunner, ...
Journal of Biological Chemistry 278 (22), 19898-19903, 2003
Regulation of peptidoglycan synthesis by outer-membrane proteins
A Typas, M Banzhaf, BB van Saparoea, J Verheul, J Biboy, RJ Nichols, ...
Cell 143 (7), 1097-1109, 2010
Antibacterial photodynamic therapy: overview of a promising approach to fight antibiotic-resistant bacterial infections
Y Liu, R Qin, SAJ Zaat, E Breukink, M Heger
Journal of clinical and translational research 1 (3), 140, 2015
Assembly and stability of nisin− lipid II pores
HE Hasper, B de Kruijff, E Breukink
Biochemistry 43 (36), 11567-11575, 2004
Natamycin blocks fungal growth by binding specifically to ergosterol without permeabilizing the membrane
YM Te Welscher, HH Ten Napel, MM Balagué, CM Souza, H Riezman, ...
Journal of Biological Chemistry 283 (10), 6393-6401, 2008
The C-terminal region of nisin is responsible for the initial interaction of nisin with the target membrane
E Breukink, C van Kraaij, RA Demel, RJ Siezen, OP Kuipers, B de Kruijff
Biochemistry 36 (23), 6968-6976, 1997
Functional interaction of human neutrophil peptide-1 with the cell wall precursor lipid II
E de Leeuw, C Li, P Zeng, C Li, M Diepeveen-de Buin, WY Lu, E Breukink, ...
FEBS letters 584 (8), 1543-1548, 2010
SecA insertion into phospholipids is stimulated by negatively charged lipids and inhibited by ATP: a monolayer study
E Breukink, RA Demel, G De Korte-Kool, B De Kruijff
Biochemistry 31 (4), 1119-1124, 1992
Molecular model for the solubilization of membranes into nanodisks by styrene maleic acid copolymers
S Scheidelaar, MC Koorengevel, JD Pardo, JD Meeldijk, E Breukink, ...
Biophysical journal 108 (2), 279-290, 2015
The C Terminus of SecA Is Involved in Both Lipid Binding and SecB Binding (∗)
E Breukink, N Nouwen, A van Raalte, S Mizushima, J Tommassen, ...
Journal of Biological Chemistry 270 (14), 7902-7907, 1995
Activities and regulation of peptidoglycan synthases
AJF Egan, J Biboy, I van't Veer, E Breukink, W Vollmer
Philosophical Transactions of the Royal Society B: Biological Sciences 370 …, 2015
Lipid II induces a transmembrane orientation of the pore-forming peptide lantibiotic nisin
HE van Heusden, B De Kruijff, E Breukink
Biochemistry 41 (40), 12171-12178, 2002
Coordination of peptidoglycan synthesis and outer membrane constriction during Escherichia coli cell division
AN Gray, AJF Egan, IL Van't Veer, J Verheul, A Colavin, A Koumoutsi, ...
elife 4, e07118, 2015
The system can't perform the operation now. Try again later.
Articles 1–20