Michel L. Tremblay
Michel L. Tremblay
Goodman Cancer Research Centre Biochemistry McGill University
Verified email at - Homepage
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Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene
M Elchebly, P Payette, E Michaliszyn, W Cromlish, S Collins, AL Loy, ...
Science 283 (5407), 1544-1548, 1999
Targeted ablation of the 25-hydroxyvitamin D 1α-hydroxylase enzyme: evidence for skeletal, reproductive, and immune dysfunction
DK Panda, D Miao, ML Tremblay, J Sirois, R Farookhi, GN Hendy, ...
Proceedings of the National Academy of Sciences 98 (13), 7498-7503, 2001
The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene.
S Vidal, ML Tremblay, G Govoni, S Gauthier, G Sebastiani, D Malo, ...
The Journal of experimental medicine 182 (3), 655-666, 1995
Attenuation of leptin action and regulation of obesity by protein tyrosine phosphatase 1B
A Cheng, N Uetani, PD Simoncic, VP Chaubey, A Lee-Loy, CJ McGlade, ...
Developmental cell 2 (4), 497-503, 2002
TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B
MP Myers, JN Andersen, A Cheng, ML Tremblay, CM Horvath, ...
Journal of Biological Chemistry 276 (51), 47771-47774, 2001
Identification of a nuclear Stat1 protein tyrosine phosphatase
J ten Hoeve, M de Jesus Ibarra-Sanchez, Y Fu, W Zhu, M Tremblay, ...
Molecular and cellular biology 22 (16), 5662-5668, 2002
Inside the human cancer tyrosine phosphatome
SG Julien, N Dubé, S Hardy, ML Tremblay
Nature Reviews Cancer 11 (1), 35-49, 2011
Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1
K Tsukiyama-Kohara, F Poulin, M Kohara, CT DeMaria, A Cheng, Z Wu, ...
Nature medicine 7 (10), 1128-1132, 2001
Impaired bone marrow microenvironment and immune function in T cell protein tyrosine phosphatase–deficient mice
KE You-Ten, ES Muise, A Itié, E Michaliszyn, J Wagner, S Jothy, WS Lapp, ...
The Journal of experimental medicine 186 (5), 683-693, 1997
The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3
PD Simoncic, A Lee-Loy, DL Barber, ML Tremblay, CJ McGlade
Current biology 12 (6), 446-453, 2002
Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis
SG Julien, N Dubé, M Read, J Penney, M Paquet, Y Han, BP Kennedy, ...
Nature genetics 39 (3), 338-346, 2007
Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts
A Angers-Loustau, JF Côté, A Charest, D Dowbenko, S Spencer, ...
The Journal of cell biology 144 (5), 1019-1031, 1999
Antitumor activity and mechanism of action of the cyclopenta [b] benzofuran, silvestrol
R Cencic, M Carrier, G Galicia-Vázquez, ME Bordeleau, R Sukarieh, ...
PloS one 4 (4), e5223, 2009
Animal model of Gaucher's disease from targeted disruption of the mouse glucocerebrosidase gene
VLJ Tybulewicz, ML Tremblay, LaMarca, R Willemsen, BK Stubblefield, ...
Nature 357 (6377), 407-410, 1992
Birc1e is the gene within the Lgn1 locus associated with resistance to Legionella pneumophila
E Diez, SH Lee, S Gauthier, Z Yaraghi, M Tremblay, S Vidal, P Gros
Nature genetics 33 (1), 55-60, 2003
Hindlimb patterning and mandible development require the Ptx1 gene
C Lanctôt, A Moreau, M Chamberland, ML Tremblay, J Drouin
Development 126 (9), 1805-1810, 1999
Mesenchymal stromal cell–derived CCL2 suppresses plasma cell immunoglobulin production via STAT3 inactivation and PAX5 induction
M Rafei, J Hsieh, S Fortier, MY Li, S Yuan, E Birman, K Forner, MN Boivin, ...
Blood, The Journal of the American Society of Hematology 112 (13), 4991-4998, 2008
Cytoplasmic protein tyrosine phosphatases, regulation and function: the roles of PTP1B and TC-PTP
A Bourdeau, N Dubé, ML Tremblay
Current opinion in cell biology 17 (2), 203-209, 2005
Coordinated action of protein tyrosine phosphatases in insulin signal transduction
A Cheng, N Dubé, F Gu, ML Tremblay
European Journal of Biochemistry 269 (4), 1050-1059, 2002
Leishmania GP63 Alters Host Signaling Through Cleavage-Activated Protein Tyrosine Phosphatases
MA Gomez, I Contreras, M Hallé, ML Tremblay, RW McMaster, M Olivier
Science signaling 2 (90), ra58-ra58, 2009
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