Lysosome biogenesis in health and disease L Bajaj, P Lotfi, R Pal, A Ronza, J Sharma, M Sardiello Journal of neurochemistry 148 (5), 573-589, 2019 | 141 | 2019 |
E6-AP promotes misfolded polyglutamine proteins for proteasomal degradation and suppresses polyglutamine protein aggregation and toxicity A Mishra, P Dikshit, S Purkayastha, J Sharma, N Nukina, NR Jana Journal of Biological Chemistry 283 (12), 7648-7656, 2008 | 103 | 2008 |
CLN8 is an endoplasmic reticulum cargo receptor that regulates lysosome biogenesis A di Ronza, L Bajaj, J Sharma, D Sanagasetti, P Lotfi, CJ Adamski, ... Nature cell biology 20 (12), 1370-1377, 2018 | 100 | 2018 |
The ubiquitin ligase E6‐AP promotes degradation of α‐synuclein SA Mulherkar, J Sharma, NR Jana Journal of neurochemistry 110 (6), 1955-1964, 2009 | 79 | 2009 |
A CLN6-CLN8 complex recruits lysosomal enzymes at the ER for Golgi transfer L Bajaj, J Sharma, A di Ronza, P Zhang, A Eblimit, R Pal, D Roman, ... The Journal of clinical investigation 130 (8), 4118-4132, 2020 | 69 | 2020 |
Sequestration of chaperones and proteasome into Lafora bodies and proteasomal dysfunction induced by Lafora disease-associated mutations of malin SNR Rao, R Maity, J Sharma, P Dey, SK Shankar, P Satishchandra, ... Human molecular genetics 19 (23), 4726-4734, 2010 | 66 | 2010 |
Capsaicin induces apoptosis through ubiquitin–proteasome system dysfunction R Maity, J Sharma, NR Jana Journal of cellular biochemistry 109 (5), 933-942, 2010 | 53 | 2010 |
Neuronatin-mediated aberrant calcium signaling and endoplasmic reticulum stress underlie neuropathology in Lafora disease J Sharma, D Mukherjee, SNR Rao, S Iyengar, SK Shankar, ... Journal of Biological Chemistry 288 (13), 9482-9490, 2013 | 52 | 2013 |
NADPH oxidase promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson’s disease R Pal, L Bajaj, J Sharma, M Palmieri, A Di Ronza, P Lotfi, A Chaudhury, ... Scientific reports 6 (1), 22866, 2016 | 51 | 2016 |
Malin regulates Wnt signaling pathway through degradation of dishevelled2 J Sharma, S Mulherkar, D Mukherjee, NR Jana Journal of Biological Chemistry 287 (9), 6830-6839, 2012 | 49 | 2012 |
Lysosomes and brain health J Sharma, A Di Ronza, P Lotfi, M Sardiello Annual review of neuroscience 41 (1), 255-276, 2018 | 46 | 2018 |
Co-chaperone CHIP stabilizes aggregate-prone malin, a ubiquitin ligase mutated in Lafora disease SNR Rao, J Sharma, R Maity, NR Jana Journal of Biological Chemistry 285 (2), 1404-1413, 2010 | 45 | 2010 |
Lafora disease ubiquitin ligase malin promotes proteasomal degradation of neuronatin and regulates glycogen synthesis J Sharma, SNR Rao, SK Shankar, P Satishchandra, NR Jana Neurobiology of disease 44 (1), 133-141, 2011 | 44 | 2011 |
Identification of a peptide inhibitor of the RPM-1· FSN-1 ubiquitin ligase complex J Sharma, ST Baker, SM Turgeon, AM Gurney, KJ Opperman, B Grill Journal of Biological Chemistry 289 (50), 34654-34666, 2014 | 20 | 2014 |
Calpain activity is negatively regulated by a KCTD7–Cullin-3 complex via non-degradative ubiquitination J Sharma, S Mulherkar, UI Chen, Y Xiong, L Bajaj, BK Cho, YA Goo, ... Cell Discovery 9 (1), 32, 2023 | 2 | 2023 |
D-mannose as a new therapy for fucokinase deficiency-related congenital disorder of glycosylation (FCSK-CDG) RT Starosta, AJ Lee, ER Toolan, M He, P Wongkittichote, EJP Daniel, ... Molecular genetics and metabolism, 108488, 2024 | 1 | 2024 |
Bowel dysmotility and enteric neuron degeneration in lysosomal storage disease mice is prevented by gene therapy MJ Jansen, LL Williams, SH Wang, EM Eultgen, K Takahashi, ... bioRxiv, 2023.05. 26.542524, 2023 | | 2023 |
TFEB degradation is regulated by an IKK/β-TrCP2 phosphorylation-ubiquitination cascade Y Xiong Washington University in St. Louis, 2023 | | 2023 |
A Study to Assess the Existing Cultural Beliefs and Associate Practices Regarding Newborn Care Among Mothers in Chandu Village at Gurugram, Haryana K Pooja, P Sharma, N Rohilla, D Mukherjee, J Sharma International journal of health sciences 6 (S2), 431-439, 0 | | |
IDENTIFICATION AND CHARACTERIZATION OF SUBSTRATES OF MALIN AN E3 LIGASE MUTATED IN LAFORA PROGRESSIVE MYOCLONUS EPILEPSY J Sharma Gurugram, 0 | | |