Joel Harp
Joel Harp
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Methylation of histone H3 by coactivator-associated arginine methyltransferase 1
BT Schurter, SS Koh, D Chen, GJ Bunick, JM Harp, BL Hanson, ...
Biochemistry 40 (19), 5747-5756, 2001
Structural basis for bile acid binding and activation of the nuclear receptor FXR
LZ Mi, S Devarakonda, JM Harp, Q Han, R Pellicciari, TM Willson, ...
Molecular cell 11 (4), 1093-1100, 2003
Asymmetries in the nucleosome core particle at 2.5 resolution
JM Harp, BL Hanson, DE Timm, GJ Bunick
Acta Crystallographica Section D: Biological Crystallography 56 (12), 1513-1534, 2000
Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen
KC Duggan, MJ Walters, J Musee, JM Harp, JR Kiefer, JA Oates, ...
Journal of biological chemistry 285 (45), 34950-34959, 2010
Macromolecular crystal annealing: overcoming increased mosaicity associated with cryocrystallography
JM Harp, DE Timm, GJ Bunick
Acta Crystallographica Section D: Biological Crystallography 54 (4), 622-628, 1998
The active site of the SET domain is constructed on a knot
SA Jacobs, JM Harp, S Devarakonda, Y Kim, F Rastinejad, ...
Nature structural biology 9 (11), 833-838, 2002
Crystal Structures of Trypanosoma brucei Sterol 14α-Demethylase and Implications for Selective Treatment of Human Infections*♦
GI Lepesheva, HW Park, TY Hargrove, B Vanhollebeke, Z Wawrzak, ...
Journal of Biological Chemistry 285 (3), 1773-1780, 2010
Structure of the heterodimeric ecdysone receptor DNA‐binding complex
S Devarakonda, JM Harp, Y Kim, A Ożyhar, F Rastinejad
The EMBO journal, 2003
Crystal structure and mechanism of a carbon–carbon bond hydrolase
DE Timm, HA Mueller, P Bhanumoorthy, JM Harp, GJ Bunick
Structure 7 (9), 1023-1033, 1999
A test of a pattern recognition system for identification of spiders
MT Do, JM Harp, KC Norris
Bulletin of Entomological Research 89 (3), 217-224, 1999
Macromolecular crystal annealing: evaluation of techniques and variables
JM Harp, BL Hanson, DE Timm, GJ Bunick
Acta Crystallographica Section D: Biological Crystallography 55 (7), 1329-1334, 1999
Chirality dependent potency enhancement and structural impact of glycol nucleic acid modification on siRNA
MK Schlegel, DJ Foster, AV Kel’in, I Zlatev, A Bisbe, M Jayaraman, ...
Journal of the American Chemical Society 139 (25), 8537-8546, 2017
Crystal Structure of a Luteoviral RNA Pseudoknot and Model for a Minimal Ribosomal Frameshifting Motif,
PS Pallan, WS Marshall, J Harp, FC Jewett, Z Wawrzak, BA Brown, A Rich, ...
Biochemistry 44 (34), 11315-11322, 2005
Discovery of the First M5-Selective and CNS Penetrant Negative Allosteric Modulator (NAM) of a Muscarinic Acetylcholine Receptor: (S)-9b-(4-Chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydro-1…
PR Gentry, M Kokubo, TM Bridges, NR Kett, JM Harp, HP Cho, E Smith, ...
Journal of medicinal chemistry 56 (22), 9351-9355, 2013
Structure and function of the genomically-encoded fosfomycin resistance enzyme, FosB, from Staphylococcus aureus
MK Thompson, M Goodman, M Keithly, N Hammer, P Cook, K Jagessar, ...
Biophysical Journal 106 (2), 45a, 2014
Structural and Chemical Aspects of Resistance to the Antibiotic Fosfomycin Conferred by FosB from Bacillus cereus
MK Thompson, ME Keithly, J Harp, PD Cook, KL Jagessar, GA Sulikowski, ...
Biochemistry 52 (41), 7350-7362, 2013
A Novel M1 PAM VU0486846 Exerts Efficacy in Cognition Models without Displaying Agonist Activity or Cholinergic Toxicity
JM Rook, JL Bertron, HP Cho, PM Garcia-Barrantes, SP Moran, ...
ACS chemical neuroscience 9 (9), 2274-2285, 2018
Synthesis and structure–activity relationships of 5, 6, 7-substituted pyrazolopyrimidines: discovery of a novel TSPO PET ligand for cancer imaging
D Tang, ET McKinley, MR Hight, MI Uddin, JM Harp, A Fu, ML Nickels, ...
Journal of medicinal chemistry 56 (8), 3429-3433, 2013
Roles of residues Arg-61 and Gln-38 of human DNA polymerase η in bypass of deoxyguanosine and 7, 8-dihydro-8-oxo-2′-deoxyguanosine
Y Su, A Patra, JM Harp, M Egli, FP Guengerich
Journal of Biological Chemistry 290 (26), 15921-15933, 2015
X-ray diffraction analysis of crystals containing twofold symmetric nucleosome core particles
JM Harp, EC Uberbacher, AE Roberson, EL Palmer, A Gewiess, ...
Acta Crystallographica Section D: Biological Crystallography 52 (2), 283-288, 1996
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