| Differential oestrogen receptor binding is associated with clinical outcome in breast cancer CS Ross-Innes, R Stark, AE Teschendorff, KA Holmes, HR Ali, ... Nature 481 (7381), 389-393, 2012 | 2068 | 2012 |
| Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2–positive breast cancer J Shou, S Massarweh, CK Osborne, AE Wakeling, S Ali, H Weiss, R Schiff Journal of the National Cancer Institute 96 (12), 926-935, 2004 | 1513 | 2004 |
| Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor α: a new model for anti-estrogen resistance RA Campbell, P Bhat-Nakshatri, NM Patel, D Constantinidou, S Ali, ... Journal of Biological Chemistry 276 (13), 9817-9824, 2001 | 1280 | 2001 |
| Endocrine-responsive breast cancer and strategies for combating resistance S Ali, RC Coombes Nature Reviews Cancer 2 (2), 101-112, 2002 | 1140 | 2002 |
| Modulation of transcriptional activation by ligand‐dependent phosphorylation of the human oestrogen receptor A/B region. S Ali, D Metzger, JM Bornert, P Chambon The EMBO journal 12 (3), 1153-1160, 1993 | 606 | 1993 |
| Trichostatin A Is a Histone Deacetylase Inhibitor with Potent Antitumor Activity against Breast Cancer in Vivo DM Vigushin, S Ali, PE Pace, N Mirsaidi, K Ito, I Adcock, RC Coombes Clinical Cancer Research 7 (4), 971-976, 2001 | 592 | 2001 |
| Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer SA Eccles, EO Aboagye, S Ali, AS Anderson, J Armes, F Berditchevski, ... Breast Cancer Research 15, 1-37, 2013 | 517 | 2013 |
| Human estrogen receptor β binds DNA in a manner similar to and dimerizes with estrogen receptor α P Pace, J Taylor, S Suntharalingam, RC Coombes, S Ali Journal of Biological Chemistry 272 (41), 25832-25838, 1997 | 447 | 1997 |
| Estrogen receptor alpha in human breast cancer: occurrence and significance S Ali, RC Coombes Journal of mammary gland biology and neoplasia 5, 271-281, 2000 | 438 | 2000 |
| Regulation of ERBB2 by oestrogen receptor–PAX2 determines response to tamoxifen A Hurtado, KA Holmes, TR Geistlinger, IR Hutcheson, RI Nicholson, ... Nature 456 (7222), 663-666, 2008 | 415 | 2008 |
| Personalized detection of circulating tumor DNA antedates breast cancer metastatic recurrence RC Coombes, K Page, R Salari, RK Hastings, A Armstrong, S Ahmed, ... Clinical Cancer Research 25 (14), 4255-4263, 2019 | 393 | 2019 |
| Phosphorylation of human estrogen receptor α by protein kinase A regulates dimerization D Chen, PE Pace, RC Coombes, S Ali Molecular and cellular biology 19 (2), 1002-1015, 1999 | 380 | 1999 |
| Enhanced estrogen receptor (ER) α, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation LA Martin, I Farmer, SRD Johnston, S Ali, C Marshall, M Dowsett Journal of Biological Chemistry 278 (33), 30458-30468, 2003 | 370 | 2003 |
| Activation of estrogen receptor α by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7 D Chen, T Riedl, E Washbrook, PE Pace, RC Coombes, JM Egly, S Ali Molecular cell 6 (1), 127-137, 2000 | 367 | 2000 |
| Characterization of the Amino-terminal Transcriptional Activation Function of the Human Estrogen Receptor in Animal and Yeast Cells (∗) D Metzger, S Ali, JM Bornert, P Chambon Journal of Biological Chemistry 270 (16), 9535-9542, 1995 | 312 | 1995 |
| Phosphorylation of human estrogen receptor α at serine 118 by two distinct signal transduction pathways revealed by phosphorylation-specific antisera D Chen, E Washbrook, N Sarwar, GJ Bates, PE Pace, ... Oncogene 21 (32), 4921-4931, 2002 | 308 | 2002 |
| Mutation analysis of cell-free DNA and single circulating tumor cells in metastatic breast cancer patients with high circulating tumor cell counts JA Shaw, DS Guttery, A Hills, D Fernandez-Garcia, K Page, BM Rosales, ... Clinical Cancer Research 23 (1), 88-96, 2017 | 224 | 2017 |
| Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogen-receptor positive and epidermal-growth-factor-receptor-positive primary breast … A Polychronis, HD Sinnett, D Hadjiminas, H Singhal, JL Mansi, ... The lancet oncology 6 (6), 383-391, 2005 | 217 | 2005 |
| Phosphorylation at serines 104 and 106 by Erk1/2 MAPK is important for estrogen receptor-α activity RS Thomas, N Sarwar, F Phoenix, RC Coombes, S Ali Journal of molecular endocrinology 40 (3), 173, 2008 | 194 | 2008 |
| Noninvasive Detection of Activating Estrogen Receptor 1 (ESR1) Mutations in Estrogen Receptor–Positive Metastatic Breast Cancer DS Guttery, K Page, A Hills, L Woodley, SD Marchese, B Rghebi, ... Clinical chemistry 61 (7), 974-982, 2015 | 189 | 2015 |
Manikandan PeriyasamyPrincipal ScientistVerified email at imperial.ac.uk
