| A unique gene regulatory network resets the human germline epigenome for development WWC Tang, S Dietmann, N Irie, HG Leitch, VI Floros, CR Bradshaw, ... Cell 161 (6), 1453-1467, 2015 | 696 | 2015 |
| Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene X D'Anglemont De Tassigny, LA Fagg, JPC Dixon, K Day, HG Leitch, ... Proceedings of the National Academy of Sciences 104 (25), 10714, 2007 | 693 | 2007 |
| Naive pluripotency is associated with global DNA hypomethylation HG Leitch, KR McEwen, A Turp, V Encheva, T Carroll, N Grabole, ... Nature structural & molecular biology 20 (3), 311-316, 2013 | 594 | 2013 |
| Hallmarks of pluripotency A De Los Angeles, F Ferrari, R Xi, Y Fujiwara, N Benvenisty, H Deng, ... Nature 525 (7570), 469-478, 2015 | 490 | 2015 |
| Epigenetic reprogramming enables the transition from primordial germ cell to gonocyte PWS Hill, HG Leitch, CE Requena, Z Sun, R Amouroux, M Roman-Trufero, ... Nature 555 (7696), 392-396, 2018 | 236 | 2018 |
| Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst GC Le Bin, S Muñoz-Descalzo, A Kurowski, H Leitch, X Lou, W Mansfield, ... Development 141 (5), 1001-1010, 2014 | 192 | 2014 |
| Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation N Grabole, J Tischler, JA Hackett, S Kim, F Tang, HG Leitch, ... EMBO reports 14 (7), 629-637, 2013 | 174 | 2013 |
| Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state HG Leitch, K Blair, W Mansfield, H Ayetey, P Humphreys, J Nichols, ... Development 137 (14), 2279-2287, 2010 | 164 | 2010 |
| Synergistic mechanisms of DNA demethylation during transition to ground-state pluripotency JA Hackett, S Dietmann, K Murakami, TA Down, HG Leitch, MA Surani Stem cell reports 1 (6), 518-531, 2013 | 154 | 2013 |
| Primordial germ-cell development and epigenetic reprogramming in mammals. HG Leitch, WW Tang, MA Surani Current topics in developmental biology 104, 149-187, 2013 | 151 | 2013 |
| Reconstitution of the oocyte transcriptional network with transcription factors N Hamazaki, H Kyogoku, H Araki, F Miura, C Horikawa, N Hamada, ... Nature 589 (7841), 264-269, 2021 | 116 | 2021 |
| Defined conditions for propagation and manipulation of mouse embryonic stem cells C Mulas, T Kalkan, F von Meyenn, HG Leitch, J Nichols, A Smith Development 146 (6), dev173146, 2019 | 114 | 2019 |
| Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion FM Piccolo, H Bagci, KE Brown, D Landeira, J Soza-Ried, A Feytout, ... Molecular cell 49 (6), 1023-1033, 2013 | 113 | 2013 |
| The mammalian germline as a pluripotency cycle HG Leitch, A Smith Development 140 (12), 2495-2501, 2013 | 81 | 2013 |
| Rebuilding pluripotency from primordial germ cells HG Leitch, J Nichols, P Humphreys, C Mulas, G Martello, C Lee, K Jones, ... Stem cell reports 1 (1), 66-78, 2013 | 79 | 2013 |
| Esrrb complementation rescues development of Nanog-null germ cells M Zhang, HG Leitch, WWC Tang, N Festuccia, E Hall-Ponsele, J Nichols, ... Cell reports 22 (2), 332-339, 2018 | 46 | 2018 |
| SLIC-CAGE: high-resolution transcription start site mapping using nanogram-levels of total RNA N Cvetesic, HG Leitch, M Borkowska, F Müller, P Carninci, P Hajkova, ... Genome Research 28 (12), 1943-1956, 2018 | 43 | 2018 |
| The impact of culture on epigenetic properties of pluripotent stem cells and pre-implantation embryos KR McEwen, HG Leitch, R Amouroux, P Hajkova Biochemical Society Transactions 41 (3), 711-719, 2013 | 37 | 2013 |
| Culture parameters for stable expansion, genetic modification and germline transmission of rat pluripotent stem cells K Blair, HG Leitch, W Mansfield, CÉ Dumeau, P Humphreys, AG Smith Biology Open 1 (1), 58-65, 2011 | 37 | 2011 |
| All models are wrong, but some are useful: Establishing standards for stem cell-based embryo models E Posfai, F Lanner, C Mulas, HG Leitch Stem Cell Reports 16 (5), 1117-1141, 2021 | 33 | 2021 |
Petra HajkovaMRC London Institute of Medical SciencesVerified email at lms.mrc.ac.uk
