W. Joost Lesterhuis
W. Joost Lesterhuis
Telethon Kids Institute, University of Western Australia
Verified email at - Homepage
Cited by
Cited by
Dendritic cell immunotherapy: mapping the way
CG Figdor, IJM de Vries, WJ Lesterhuis, CJM Melief
Nature medicine 10 (5), 475-480, 2004
Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy
IJM De Vries, WJ Lesterhuis, JO Barentsz, P Verdijk, JH Van Krieken, ...
Nature biotechnology 23 (11), 1407-1413, 2005
Effective migration of antigen-pulsed dendritic cells to lymph nodes in melanoma patients is determined by their maturation state
IJM De Vries, DJEB Krooshoop, NM Scharenborg, WJ Lesterhuis, ...
Cancer research 63 (1), 12-17, 2003
Cancer immunotherapy–revisited
WJ Lesterhuis, JBAG Haanen, CJA Punt
Nature reviews Drug discovery 10 (8), 591-600, 2011
Molecular pathways: the immunogenic effects of platinum-based chemotherapeutics
SV Hato, A Khong, IJM de Vries, WJ Lesterhuis
Clinical Cancer Research 20 (11), 2831-2837, 2014
Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients
IJM de Vries, WJ Lesterhuis, NM Scharenborg, LPH Engelen, DJ Ruiter, ...
Clinical cancer research 9 (14), 5091-5100, 2003
Programmed death ligand 2 in cancer‐induced immune suppression
EN Rozali, SV Hato, BW Robinson, RA Lake, WJ Lesterhuis
Journal of Immunology Research 2012 (1), 656340, 2012
Platinum-based drugs disrupt STAT6-mediated suppression of immune responses against cancer in humans and mice
WJ Lesterhuis, CJA Punt, SV Hato, D Eleveld-Trancikova, BJH Jansen, ...
The Journal of clinical investigation 121 (8), 3100-3108, 2011
Dendritic cell vaccination in combination with anti-CD25 monoclonal antibody treatment: a phase I/II study in metastatic melanoma patients
JFM Jacobs, CJA Punt, WJ Lesterhuis, RPM Sutmuller, HMH Brouwer, ...
Clinical Cancer Research 16 (20), 5067-5078, 2010
Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients
P Verdijk, EHJG Aarntzen, WJ Lesterhuis, ACI Boullart, E Kok, ...
Clinical Cancer Research 15 (7), 2531-2540, 2009
Immunomonitoring tumor-specific T cells in delayed-type hypersensitivity skin biopsies after dendritic cell vaccination correlates with clinical outcome.
IJM de Vries, MR Bernsen, WJ Lesterhuis, NM Scharenborg, SP Strijk, ...
Dynamic versus static biomarkers in cancer immune checkpoint blockade: unravelling complexity
WJ Lesterhuis, A Bosco, MJ Millward, M Small, AK Nowak, RA Lake
Nature Reviews Drug Discovery 16 (4), 264-272, 2017
Route of administration modulates the induction of dendritic cell vaccine–induced antigen-specific T cells in advanced melanoma patients
WJ Lesterhuis, IJM de Vries, G Schreibelt, AJA Lambeck, EHJG Aarntzen, ...
Clinical Cancer Research 17 (17), 5725-5735, 2011
Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironment
RM Zemek, E De Jong, WL Chin, IS Schuster, VS Fear, TH Casey, ...
Science translational medicine 11 (501), eaav7816, 2019
A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice
WJ Aston, DE Hope, AK Nowak, BW Robinson, RA Lake, WJ Lesterhuis
BMC cancer 17, 1-10, 2017
Targeting CD4+ T-Helper Cells Improves the Induction of Antitumor Responses in Dendritic Cell–Based Vaccination
EHJG Aarntzen, IJM De Vries, WJ Lesterhuis, D Schuurhuis, JFM Jacobs, ...
Cancer research 73 (1), 19-29, 2013
Synergistic effect of CTLA-4 blockade and cancer chemotherapy in the induction of anti-tumor immunity
WJ Lesterhuis, J Salmons, AK Nowak, EN Rozali, A Khong, IM Dick, ...
PloS one 8 (4), e61895, 2013
Dendritic cell vaccines in melanoma: from promise to proof?
WJ Lesterhuis, E Aarntzen, IJM De Vries, DH Schuurhuis, CG Figdor, ...
Critical reviews in oncology/hematology 66 (2), 118-134, 2008
Phenotypical and functional characterization of clinical grade dendritic cells
IJM de Vries, AAO Eggert, NM Scharenborg, JLM Vissers, WJ Lesterhuis, ...
Journal of immunotherapy 25 (5), 429-438, 2002
Chemotherapy and immunotherapy: mapping the road ahead
AM Cook, WJ Lesterhuis, AK Nowak, RA Lake
Current opinion in immunology 39, 23-29, 2016
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