David Tough
David Tough
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Cited by
Cited by
Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15
X Zhang, S Sun, I Hwang, DF Tough, J Sprent
Immunity 8 (5), 591-599, 1998
Induction of bystander T cell proliferation by viruses and type I interferon in vivo
DF Tough, P Borrow, J Sprent
Science 272 (5270), 1947-1950, 1996
Type I interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo
A Le Bon, G Schiavoni, G D'Agostino, I Gresser, F Belardelli, DF Tough
Immunity 14 (4), 461-470, 2001
Turnover of naive-and memory-phenotype T cells.
DF Tough, J Sprent
The Journal of experimental medicine 179 (4), 1127-1135, 1994
Cross-priming of CD8+ T cells stimulated by virus-induced type I interferon
A Le Bon, N Etchart, C Rossmann, M Ashton, S Hou, D Gewert, P Borrow, ...
Nature immunology 4 (10), 1009-1015, 2003
Links between innate and adaptive immunity via type I interferon
A Le Bon, DF Tough
Current opinion in immunology 14 (4), 432-436, 2002
Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription
MU Kaikkonen, NJ Spann, S Heinz, CE Romanoski, KA Allison, ...
Molecular cell 51 (3), 310-325, 2013
Type I interferons produced by dendritic cells promote their phenotypic and functional activation
M Montoya, G Schiavoni, F Mattei, I Gresser, F Belardelli, P Borrow, ...
Blood, The Journal of the American Society of Hematology 99 (9), 3263-3271, 2002
Initial T cell frequency dictates memory CD8+ T cell lineage commitment
AL Marzo, KD Klonowski, AL Bon, P Borrow, DF Tough, L Lefrançois
Nature immunology 6 (8), 793-799, 2005
IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation
F Mattei, G Schiavoni, F Belardelli, DF Tough
The Journal of Immunology 167 (3), 1179-1187, 2001
Developmental kinetics and lifespan of dendritic cells in mouse lymphoid organs
AT Kamath, S Henri, F Battye, DF Tough, K Shortman
Blood, The Journal of the American Society of Hematology 100 (5), 1734-1741, 2002
Lymphocyte life-span and memory
J Sprent, DF Tough
Science 265 (5177), 1395-1400, 1994
The development, maturation, and turnover rate of mouse spleen dendritic cell populations
AT Kamath, J Pooley, MA O’Keeffe, D Vremec, Y Zhan, AM Lew, ...
The Journal of Immunology 165 (12), 6762-6770, 2000
Type I interferon-mediated stimulation of T cells by CpG DNA
S Sun, X Zhang, DF Tough, J Sprent
The Journal of experimental medicine 188 (12), 2335-2342, 1998
IL-15 promotes the survival of naive and memory phenotype CD8+ T cells
M Berard, K Brandt, SB Paus, DF Tough
The Journal of Immunology 170 (10), 5018-5026, 2003
Cutting edge: enhancement of antibody responses through direct stimulation of B and T cells by type I IFN
A Le Bon, C Thompson, E Kamphuis, V Durand, C Rossmann, U Kalinke, ...
The Journal of Immunology 176 (4), 2074-2078, 2006
T cell stimulation in vivo by lipopolysaccharide (LPS)
DF Tough, S Sun, J Sprent
The Journal of experimental medicine 185 (12), 2089-2094, 1997
Direct stimulation of T cells by type I IFN enhances the CD8+ T cell response during cross-priming
A Le Bon, V Durand, E Kamphuis, C Thompson, S Bulfone-Paus, ...
The Journal of Immunology 176 (8), 4682-4689, 2006
In vivo kinetics of human natural killer cells: the effects of ageing and acute and chronic viral infection
Y Zhang, DL Wallace, CM De Lara, H Ghattas, B Asquith, A Worth, ...
Immunology 121 (2), 258-265, 2007
Qualitative differences between naive and memory T cells
M Berard, DF Tough
Immunology 106 (2), 127, 2002
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