Monica Schenone
Monica Schenone
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Lenalidomide causes selective degradation of IKZF1 and IKZF3 in multiple myeloma cells
J Krönke, ND Udeshi, A Narla, P Grauman, SN Hurst, M McConkey, ...
Science 343 (6168), 301-305, 2014
Target identification and mechanism of action in chemical biology and drug discovery
M Schenone, V Dančík, BK Wagner, PA Clemons
Nature chemical biology 9 (4), 232-240, 2013
Selective killing of cancer cells by a small molecule targeting the stress response to ROS
L Raj, T Ide, AU Gurkar, M Foley, M Schenone, X Li, NJ Tolliday, ...
Nature 475 (7355), 231-234, 2011
Identifying the proteins to which small-molecule probes and drugs bind in cells
SE Ong, M Schenone, AA Margolin, X Li, K Do, MK Doud, DR Mani, ...
Proceedings of the National Academy of Sciences 106 (12), 4617-4622, 2009
The NORAD lncRNA assembles a topoisomerase complex critical for genome stability
M Munschauer, CT Nguyen, K Sirokman, CR Hartigan, L Hogstrom, ...
Nature 561 (7721), 132-136, 2018
WRN helicase is a synthetic lethal target in microsatellite unstable cancers
EM Chan, T Shibue, JM McFarland, B Gaeta, M Ghandi, N Dumont, ...
Nature 568 (7753), 551-556, 2019
The blood coagulation cascade
M Schenone, BC Furie, B Furie
Current opinion in hematology 11 (4), 272-277, 2004
Rps14 haploinsufficiency causes a block in erythroid differentiation mediated by S100A8 and S100A9
RK Schneider, M Schenone, MV Ferreira, R Kramann, CE Joyce, ...
Nature medicine 22 (3), 288-297, 2016
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL
Q Wen, B Goldenson, SJ Silver, M Schenone, V Dancik, Z Huang, ...
Cell 150 (3), 575-589, 2012
Type 2 diabetes variants disrupt function of SLC16A11 through two distinct mechanisms
V Rusu, E Hoch, JM Mercader, DE Tenen, M Gymrek, CR Hartigan, ...
Cell 170 (1), 199-212. e20, 2017
Phenotypic drug discovery: recent successes, lessons learned and new directions
F Vincent, A Nueda, J Lee, M Schenone, M Prunotto, M Mercola
Nature Reviews Drug Discovery 21 (12), 899-914, 2022
Development of a novel B-cell lymphoma 6 (BCL6) PROTAC to provide insight into small molecule targeting of BCL6
W McCoull, T Cheung, E Anderson, P Barton, J Burgess, K Byth, Q Cao, ...
ACS Chemical Biology 13 (11), 3131-3141, 2018
C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions
V Mohanan, T Nakata, AN Desch, C Lévesque, A Boroughs, G Guzman, ...
Science 359 (6380), 1161-1166, 2018
The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer
M Gandhi, M Groß, JM Holler, SAA Coggins, N Patil, JH Leupold, ...
Nature communications 11 (1), 3214, 2020
Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics
L De Waal, TA Lewis, MG Rees, A Tsherniak, X Wu, PS Choi, L Gechijian, ...
Nature chemical biology 12 (2), 102-108, 2016
Binding of TMPRSS2-ERG to BAF chromatin remodeling complexes mediates prostate oncogenesis
GJ Sandoval, JL Pulice, H Pakula, M Schenone, DY Takeda, M Pop, ...
Molecular cell 71 (4), 554-566. e7, 2018
Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation
A Basak, M Munschauer, CA Lareau, KE Montbleau, JC Ulirsch, ...
Nature genetics 52 (2), 138-145, 2020
Structure and binding determinants of the recombinant kringle-2 domain of human plasminogen to an internal peptide from a group A Streptococcal surface protein
JL Rios-Steiner, M Schenone, I Mochalkin, A Tulinsky, FJ Castellino
Journal of molecular biology 308 (4), 705-719, 2001
Domain interactions between streptokinase and human plasminogen
JA Loy, X Lin, M Schenone, FJ Castellino, XC Zhang, J Tang
Biochemistry 40 (48), 14686-14695, 2001
Empirical Bayes analysis of quantitative proteomics experiments
AA Margolin, SE Ong, M Schenone, R Gould, SL Schreiber, SA Carr, ...
PloS one 4 (10), e7454, 2009
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