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Rune Busk Damgaard
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OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin
K Keusekotten, PR Elliott, L Glockner, BK Fiil, RB Damgaard, Y Kulathu, ...
Cell 153 (6), 1312-1326, 2013
4802013
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity
RB Damgaard, U Nachbur, M Yabal, WWL Wong, BK Fiil, M Kastirr, ...
Molecular cell 46 (6), 746-758, 2012
4062012
The deubiquitinase OTULIN is an essential negative regulator of inflammation and autoimmunity
RB Damgaard, JA Walker, P Marco-Casanova, NV Morgan, ...
Cell 166 (5), 1215-1230. e20, 2016
3092016
OTULIN restricts Met1-linked ubiquitination to control innate immune signaling
BK Fiil, RB Damgaard, SA Wagner, K Keusekotten, M Fritsch, ...
Molecular cell 50 (6), 818-830, 2013
2682013
XIAP restricts TNF-and RIP3-dependent cell death and inflammasome activation
M Yabal, N Müller, H Adler, N Knies, CJ Groß, RB Damgaard, ...
Cell reports 7 (6), 1796-1808, 2014
2612014
X-linked inhibitor of apoptosis (XIAP) deficiency: the spectrum of presenting manifestations beyond hemophagocytic lymphohistiocytosis
C Speckmann, K Lehmberg, MH Albert, RB Damgaard, M Fritsch, ...
Clinical immunology 149 (1), 133-141, 2013
1832013
CYLD limits Lys63-and Met1-linked ubiquitin at receptor complexes to regulate innate immune signaling
M Hrdinka, BK Fiil, M Zucca, D Leske, K Bagola, M Yabal, PR Elliott, ...
Cell reports 14 (12), 2846-2858, 2016
1552016
Disease‐causing mutations in the XIAP BIR 2 domain impair NOD 2‐dependent immune signalling
RB Damgaard, BK Fiil, C Speckmann, M Yabal, U Stadt, S Bekker‐Jensen, ...
EMBO molecular medicine 5 (8), 1278-1295, 2013
1522013
Apoptotic cell death in disease—Current understanding of the NCCD 2023
I Vitale, F Pietrocola, E Guilbaud, SA Aaronson, JM Abrams, D Adam, ...
Cell Death & Differentiation 30 (5), 1097-1154, 2023
1142023
The ubiquitin system: from cell signalling to disease biology and new therapeutic opportunities
RB Damgaard
Cell Death & Differentiation 28 (2), 423-426, 2021
1122021
Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity
RB Damgaard, M Gyrd-Hansen
Discovery medicine 11 (58), 221-231, 2011
992011
OTULIN deficiency in ORAS causes cell type‐specific LUBAC degradation, dysregulated TNF signalling and cell death
RB Damgaard, PR Elliott, KN Swatek, ER Maher, P Stepensky, O Elpeleg, ...
EMBO molecular medicine 11 (3), e9324, 2019
932019
OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer
RB Damgaard, HE Jolin, MED Allison, SE Davies, HL Titheradge, ...
Cell Death & Differentiation 27 (5), 1457-1474, 2020
542020
Met1-linked ubiquitin signalling in health and disease: inflammation, immunity, cancer, and beyond
AS Jahan, CR Elbæk, RB Damgaard
Cell Death & Differentiation 28 (2), 473-492, 2021
432021
WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity
CR Elbæk, V Petrosius, J Benada, L Erichsen, RB Damgaard, ...
Cell reports 38 (3), 2022
332022
Phospholipids alter activity and stability of mitochondrial membrane-bound ubiquitin ligase MARCH5
L Merklinger, J Bauer, PA Pedersen, RB Damgaard, JP Morth
Life Science Alliance 5 (8), 2022
72022
Ester‐linked ubiquitination by HOIL‐1 controls immune signalling by shaping the linear ubiquitin landscape
JN Pruneda, RB Damgaard
The FEBS Journal 288 (20), 5903-5908, 2021
62021
NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62
N Furthmann, V Bader, L Angersbach, A Blusch, S Goel, ...
Nature communications 14 (1), 8368, 2023
5*2023
Legionella dismantles linear ubiquitin
RB Damgaard, JN Pruneda
Nature Microbiology 4 (8), 1244-1245, 2019
22019
Universiteterne har brug for en reformpause
K Kropp, K Vallgårda, AH Laustsen-Kiel, N Albrechtsen, L Sylow, ...
Berlingske Tidende, 2023
2023
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