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Edward Hookway
Edward Hookway
Verified email at nhs.net
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Year
Structural analysis of human KDM5B guides histone demethylase inhibitor development
C Johansson, S Velupillai, A Tumber, A Szykowska, ES Hookway, ...
Nature chemical biology 12 (7), 539-545, 2016
1782016
Potent and selective KDM5 inhibitor stops cellular demethylation of H3K4me3 at transcription start sites and proliferation of MM1S myeloma cells
A Tumber, A Nuzzi, ES Hookway, SB Hatch, S Velupillai, C Johansson, ...
Cell chemical biology 24 (3), 371-380, 2017
1242017
Genetic dissection of a Leishmania flagellar proteome demonstrates requirement for directional motility in sand fly infections
T Beneke, F Demay, E Hookway, N Ashman, H Jeffery, J Smith, J Valli, ...
PLoS pathogens 15 (6), e1007828, 2019
1012019
Inhibition of histone H3K27 demethylases selectively modulates inflammatory phenotypes of natural killer cells
A Cribbs, ES Hookway, G Wells, M Lindow, S Obad, H Oerum, RK Prinjha, ...
Journal of Biological Chemistry 293 (7), 2422-2437, 2018
852018
Synovial chondromatosis and soft tissue chondroma: extraosseous cartilaginous tumor defined by FN1 gene rearrangement
F Amary, L Perez-Casanova, H Ye, L Cottone, AC Strobl, P Cool, ...
Modern Pathology 32 (12), 1762-1771, 2019
672019
Dendritic and mast cell involvement in the inflammatory response to primary malignant bone tumours
Y Inagaki, E Hookway, KA Williams, AB Hassan, U Oppermann, Y Tanaka, ...
Clinical sarcoma research 6, 1-8, 2016
542016
Inhibition of histone H3K27 demethylases inactivates brachyury (TBXT) and promotes chordoma cell death
L Cottone, AP Cribbs, G Khandelwal, G Wells, L Ligammari, M Philpott, ...
Cancer Research 80 (20), 4540-4551, 2020
342020
A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report
DJ Barnes, E Hookway, N Athanasou, T Kashima, U Oppermann, ...
BMC cancer 16, 1-14, 2016
332016
Non-competitive cyclic peptides for targeting enzyme–substrate complexes
TE McAllister, TL Yeh, MI Abboud, IKH Leung, ES Hookway, ONF King, ...
Chemical Science 9 (20), 4569-4578, 2018
312018
Dentine matrix protein 1 (DMP-1) is a marker of bone formation and mineralisation in soft tissue tumours
Y Inagaki, TG Kashima, ES Hookway, Y Tanaka, AB Hassan, ...
Virchows Archiv 466, 445-452, 2015
192015
Sclerostin expression in bone tumours and tumour‐like lesions
Y Inagaki, ES Hookway, TG Kashima, M Munemoto, Y Tanaka, ...
Histopathology 69 (3), 470-478, 2016
142016
The role of calcium and nicotinic acid adenine dinucleotide phosphate (NAADP) in human osteoclast formation and resorption
X Cheng, ES Hookway, T Kashima, U Oppermann, A Galione, ...
Calcified tissue international 96, 73-79, 2015
142015
Linker histone H1. 2 directs genome-wide chromatin Association of the Retinoblastoma Tumor Suppressor Protein and Facilitates its Function
S Munro, ES Hookway, M Floderer, SM Carr, R Konietzny, BM Kessler, ...
Cell reports 19 (11), 2193-2201, 2017
102017
Epigenetic inactivation of oncogenic brachyury (TBXT) by H3K27 histone demethylase controls chordoma cell survival
L Cottone, ES Hookway, A Cribbs, G Wells, P Lombard, L Ligammari, ...
BioRxiv, 432005, 2018
42018
The role of the lysine demethylases KDM5 and KDM6 in bone malignancies
E Hookway
University of Oxford, 2016
42016
Histone demethylase inhibition As a novel therapeutic strategy in myeloma
C Pawlyn, E Hookway, P Cain, L Pliuskys, MF Kaiser, M Bright, ...
Blood 124 (21), 2087, 2014
42014
Utility of VS38c in the diagnostic and prognostic assessment of osteosarcoma and other bone tumours/tumour-like lesions
ES Hookway, Z Orosz, Y Uchihara, A Grigoriadis, AB Hassan, ...
Clinical Sarcoma Research 7, 1-8, 2017
32017
A compound screen reveals potential novel therapeutic targets for chordoma: metabolic stress response and epigenetic control of brachyury
L Cottone, E Hookway, G Wells, L Ligammari, P Lombard, R Mazitschek, ...
Cancer Research 78 (13_Supplement), 1949-1949, 2018
22018
Synovial Chondromatosis, Synovial Chondrosarcoma and Soft Tissue Chondroma: Adding to the Group of Calcifying Tumours with a FN1 Gene Rearrangement
L Perez-Casanova, F Amary, Y Hongtao, L Cottone, A Strobl, F Berisha, ...
JOURNAL OF PATHOLOGY 249, S20-S20, 2019
2019
The Molecular Landscape of Malignant Peripheral Nerve Sheath Tumour (MPNST)
D Lindsay, E Hookway, C Steele, P Lombard, M Gupta, F Amary, ...
JOURNAL OF PATHOLOGY 248, S5-S5, 2019
2019
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Articles 1–20