Iterative optimization yields Mcl-1–targeting stapled peptides with selective cytotoxicity to Mcl-1–dependent cancer cells R Rezaei Araghi, GH Bird, JA Ryan, JM Jenson, M Godes, JR Pritz, ... Proceedings of the National Academy of Sciences 115 (5), E886-E895, 2018 | 88 | 2018 |
Nanoparticle‐induced folding and fibril formation of coiled‐coil‐based model peptides SC Wagner, M Roskamp, M Pallerla, RR Araghi, S Schlecht, B Koksch Small 6 (12), 1321-1328, 2010 | 81 | 2010 |
Designing helical peptide inhibitors of protein–protein interactions RR Araghi, AE Keating Current opinion in structural biology 39, 27-38, 2016 | 77 | 2016 |
Rapid Optimization of Mcl-1 Inhibitors using Stapled Peptide Libraries Including Non-Natural Side Chains R Rezaei Araghi, JA Ryan, A Letai, AE Keating ACS Chemical Biology, 2016 | 53 | 2016 |
Intramolecular Charge Interactions as a Tool to Control the Coiled‐Coil‐to‐Amyloid Transformation K Pagel, SC Wagner, R Rezaei Araghi, H von Berlepsch, C Böttcher, ... Chemistry–A European Journal 14 (36), 11442-11451, 2008 | 43 | 2008 |
A beta/gamma Motif to Mimic alpha-Helical Turns in Proteins RR Araghi, C Jäckel, H Cölfen, M Salwiczek, A Völkel, SC Wagner, ... | 30 | 2010 |
A helix-forming αβγ-chimeric peptide with catalytic activity: a hybrid peptide ligase RR Araghi, B Koksch Chemical Communications 47 (12), 3544-3546, 2011 | 23 | 2011 |
A systematic study of fundamentals in α-helical coiled coil mimicry by alternating sequences of β-and γ-amino acids R Rezaei Araghi, C Baldauf, UIM Gerling, CD Cadicamo, B Koksch Amino Acids 41, 733-742, 2011 | 15 | 2011 |
An Unusual Interstrand H-Bond Stabilizes the Heteroassembly of Helical αβγ-Chimeras with Natural Peptides EK Nyakatura, R Rezaei Araghi, J Mortier, S Wieczorek, C Baldauf, ... ACS Chemical Biology 9 (3), 613-616, 2014 | 13 | 2014 |
A β/γ Motif to Mimic α‐Helical Turns in Proteins R Rezaei Araghi, C Jäckel, H Cölfen, M Salwiczek, A Völkel, SC Wagner, ... ChemBioChem 11 (3), 335-339, 2010 | 13 | 2010 |
β-and γ-Amino Acids at α-Helical Interfaces: Toward the Formation of Highly Stable Foldameric Coiled Coils EK Nyakatura, J Mortier, VS Radtke, S Wieczorek, R Rezaei Araghi, ... ACS Medicinal Chemistry Letters 5 (12), 1300-1303, 2014 | 11 | 2014 |
The protofilament architecture of a de novo designed coiled coil-based amyloidogenic peptide MS de Freitas, RR Araghi, E Brandenburg, J Leiterer, F Emmerling, ... Journal of Structural Biology 203 (3), 263-272, 2018 | 5 | 2018 |
Selective Mcl-1 binding peptides R Rezaei-Araghi, A Keating, GH Bird, L Walensky US Patent 11,142,554, 2021 | 4 | 2021 |
Investigation of the network of preferred interactions in an artificial coiled-coil association using the peptide array technique RR Araghi, CC Mahrenholz, R Volkmer, B Koksch Beilstein Journal of Organic Chemistry 8 (1), 640-649, 2012 | 4 | 2012 |
α-Helical Coiled Coil Mimicry by Alternating Sequences of β-and γ-Amino Acids RR Araghi Freie Universität Berlin, 2011 | 3 | 2011 |
Collections of peptides, peptide agents, and methods of use thereof JH Mcgee, TM Thomson, SCT Wahl, GL Verdine, RR Araghi, YM Zhang, ... US Patent App. 17/269,939, 2021 | 2 | 2021 |
Selective mcl-1 binding peptides R Rezaei-Araghi, A Keating US Patent App. 15/772,226, 2019 | 2 | 2019 |
A protein chimera with a beta/gamma-motif mimicking alpha-helical turns B Koksch, RR Araghi, C Baldauf, MT Pisabarro Amino Acids 37, 42-42, 2009 | 1 | 2009 |
Selective mcl-1 binding peptides R Rezaei-Araghi, AE Keating US Patent App. 18/295,214, 2024 | | 2024 |
Bioactive β-and γ-peptides Z Mahfouz, EK Nyakatura, RR Araghi, J Mortier, D Gjorgjevikj, N Klishin, ... Journal of peptide science: the official journal of the European Peptide …, 2022 | | 2022 |