CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes LA Gilbert, MH Larson, L Morsut, Z Liu, GA Brar, SE Torres, ... Cell 154 (2), 442-451, 2013 | 4397 | 2013 |
STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels O Brandman, J Liou, WS Park, T Meyer Cell 131 (7), 1327-1339, 2007 | 844 | 2007 |
A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress O Brandman, J Stewart-Ornstein, D Wong, A Larson, CC Williams, GW Li, ... Cell 151 (5), 1042-1054, 2012 | 664 | 2012 |
Feedback loops shape cellular signals in space and time O Brandman, T Meyer Science 322 (5900), 390-395, 2008 | 536 | 2008 |
Interlinked fast and slow positive feedback loops drive reliable cell decisions O Brandman, JE Ferrell Jr, R Li, T Meyer Science 310 (5747), 496-498, 2005 | 533 | 2005 |
Ribosome-associated protein quality control O Brandman, RS Hegde Nature structural & molecular biology 23 (1), 7-15, 2016 | 427 | 2016 |
Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains PS Shen, J Park, Y Qin, X Li, K Parsawar, MH Larson, J Cox, Y Cheng, ... Science 347 (6217), 75-78, 2015 | 294 | 2015 |
Functional repurposing revealed by comparing S. pombe and S. cerevisiae genetic interactions A Frost, MG Elgort, O Brandman, C Ives, SR Collins, L Miller-Vedam, ... Cell 149 (6), 1339-1352, 2012 | 172 | 2012 |
Asc1, Hel2, and Slh1 couple translation arrest to nascent chain degradation CS Sitron, JH Park, O Brandman Rna 23 (5), 798-810, 2017 | 130 | 2017 |
Single cell analysis of yeast replicative aging using a new generation of microfluidic device Y Zhang, C Luo, K Zou, Z Xie, O Brandman, Q Ouyang, H Li PloS one 7 (11), e48275, 2012 | 126 | 2012 |
Cellular control of viscosity counters changes in temperature and energy availability LB Persson, VS Ambati, O Brandman Cell 183 (6), 1572-1585. e16, 2020 | 121 | 2020 |
Molecular phenotyping of aging in single yeast cells using a novel microfluidic device Z Xie, Y Zhang, K Zou, O Brandman, C Luo, Q Ouyang, H Li Aging cell 11 (4), 599-606, 2012 | 119 | 2012 |
Crawler-friendly web servers O Brandman, J Cho, H Garcia-Molina, N Shivakumar ACM SIGMETRICS Performance Evaluation Review 28 (2), 9-14, 2000 | 118 | 2000 |
CAT tails drive degradation of stalled polypeptides on and off the ribosome CS Sitron, O Brandman Nature structural & molecular biology 26 (6), 450-459, 2019 | 80 | 2019 |
Detection and degradation of stalled nascent chains via ribosome-associated quality control CS Sitron, O Brandman Annual review of biochemistry 89 (1), 417-442, 2020 | 72 | 2020 |
MISTERMINATE mechanistically links mitochondrial dysfunction with proteostasis failure Z Wu, I Tantray, J Lim, S Chen, Y Li, Z Davis, C Sitron, J Dong, S Gispert, ... Molecular cell 75 (4), 835-848. e8, 2019 | 69 | 2019 |
Protein Evolution in the Context of Drosophila Development JC Davis, O Brandman, DA Petrov Journal of molecular evolution 60, 774-785, 2005 | 66 | 2005 |
Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress A Igbaria, PI Merksamer, A Trusina, F Tilahun, JR Johnson, O Brandman, ... Proceedings of the National Academy of Sciences 116 (23), 11291-11298, 2019 | 41 | 2019 |
Oxaliplatin disrupts nucleolar function through biophysical disintegration HB Schmidt, ZA Jaafar, BE Wulff, JJ Rodencal, K Hong, MO Aziz-Zanjani, ... Cell reports 41 (6), 2022 | 28 | 2022 |
Aggregation of CAT tails blocks their degradation and causes proteotoxicity in S. cerevisiae CS Sitron, JH Park, JM Giafaglione, O Brandman PLoS One 15 (1), e0227841, 2020 | 28 | 2020 |