|Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides|
N Iwamoto, DCD Butler, N Svrzikapa, S Mohapatra, I Zlatev, DWY Sah, ...
Nature biotechnology 35 (9), 845-851, 2017
|Chemokine expression and control of muscle cell migration during myogenesis|
CA Griffin, LH Apponi, KK Long, GK Pavlath
Journal of cell science 123 (18), 3052-3060, 2010
|Actively transcribed GAL genes can be physically linked to the nuclear pore by the SAGA chromatin modifying complex|
R Luthra, SC Kerr, MT Harreman, LH Apponi, MB Fasken, S Ramineni, ...
Journal of Biological Chemistry 282 (5), 3042-3049, 2007
|Loss of nuclear poly (A)-binding protein 1 causes defects in myogenesis and mRNA biogenesis|
LH Apponi, SW Leung, KR Williams, SR Valentini, AH Corbett, GK Pavlath
Human molecular genetics 19 (6), 1058-1065, 2010
|PABPN 1: molecular function and muscle disease|
A Banerjee, LH Apponi, GK Pavlath, AH Corbett
The FEBS journal 280 (17), 4230-4250, 2013
|Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans|
CH Pak, M Garshasbi, K Kahrizi, C Gross, LH Apponi, JJ Noto, SM Kelly, ...
Proceedings of the National Academy of Sciences 108 (30), 12390-12395, 2011
|RNA-binding proteins and gene regulation in myogenesis|
LH Apponi, AH Corbett, GK Pavlath
Trends in pharmacological sciences 32 (11), 652-658, 2011
|Inhibition of glycolate oxidase with dicer-substrate siRNA reduces calcium oxalate deposition in a mouse model of primary hyperoxaluria type 1|
C Dutta, N Avitahl-Curtis, N Pursell, ML Cohen, B Holmes, R Diwanji, ...
Molecular Therapy 24 (4), 770-778, 2016
|H2B ubiquitylation controls the formation of export-competent mRNP|
A Vitaliano-Prunier, A Babour, L Hérissant, L Apponi, T Margaritis, ...
Molecular cell 45 (1), 132-139, 2012
|Structural modeling and mutational analysis of yeast eukaryotic translation initiation factor 5A reveal new critical residues and reinforce its involvement in protein synthesis|
CAO Dias, VSP Cano, SM Rangel, LH Apponi, MC Frigieri, JRC Muniz, ...
The FEBS journal 275 (8), 1874-1888, 2008
|The mitogen-activated protein kinase Slt2 regulates nuclear retention of non-heat shock mRNAs during heat shock-induced stress|
SR Carmody, EJ Tran, LH Apponi, AH Corbett, SR Wente
Molecular and Cellular Biology 30 (21), 5168-5179, 2010
|Recognition of polyadenosine RNA by the zinc finger domain of nuclear poly (A) RNA-binding protein 2 (Nab2) is required for correct mRNA 3′-end formation|
SM Kelly, SW Leung, LH Apponi, AM Bramley, EJ Tran, JA Chekanova, ...
Journal of Biological Chemistry 285 (34), 26022-26032, 2010
|Splice variants of the human ZC3H14 gene generate multiple isoforms of a zinc finger polyadenosine RNA binding protein|
SW Leung, LH Apponi, OE Cornejo, CM Kitchen, SR Valentini, ...
Gene 439 (1-2), 71-78, 2009
|Expression of the Interleukin‐10 Signaling Pathway Genes in Individuals With Down Syndrome and Periodontitis|
LB Cavalcante, MH Tanaka, JR Pires, L Henrique Apponi, ...
Journal of periodontology 83 (7), 926-935, 2012
|Novel mouse models of oculopharyngeal muscular dystrophy (OPMD) reveal early onset mitochondrial defects and suggest loss of PABPN1 may contribute to pathology|
KE Vest, BL Phillips, A Banerjee, LH Apponi, EB Dammer, W Xu, D Zheng, ...
Human Molecular Genetics 26 (17), 3235-3252, 2017
|Control of mRNA stability contributes to low levels of nuclear poly (A) binding protein 1 (PABPN1) in skeletal muscle|
LH Apponi, AH Corbett, GK Pavlath
Skeletal muscle 3, 1-9, 2013
|Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides|
P Monian, C Shivalila, G Lu, M Shimizu, D Boulay, K Bussow, M Byrne, ...
Nature Biotechnology 40 (7), 1093-1102, 2022
|Expression of interferon-γ, interferon-α and related genes in individuals with Down syndrome and periodontitis|
MH Tanaka, EMA Giro, LB Cavalcante, JR Pires, LH Apponi, SR Valentini, ...
Cytokine 60 (3), 875-881, 2012
|An interaction between two RNA binding proteins, Nab2 and Pub1, links mRNA processing/export and mRNA stability|
LH Apponi, SM Kelly, MT Harreman, AN Lehner, AH Corbett, SR Valentini
Molecular and cellular biology 27 (18), 6569-6579, 2007
|Synthetic lethality between eIF5A and Ypt1 reveals a connection between translation and the secretory pathway in yeast|
MC Frigieri, MVS João Luiz, LH Apponi, CF Zanelli, SR Valentini
Molecular Genetics and Genomics 280, 211-221, 2008