Luciano Apponi
Luciano Apponi
Research Scientist
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Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides
N Iwamoto, DCD Butler, N Svrzikapa, S Mohapatra, I Zlatev, DWY Sah, ...
Nature biotechnology 35 (9), 845-851, 2017
Chemokine expression and control of muscle cell migration during myogenesis
CA Griffin, LH Apponi, KK Long, GK Pavlath
Journal of cell science 123 (18), 3052-3060, 2010
Loss of nuclear poly (A)-binding protein 1 causes defects in myogenesis and mRNA biogenesis
LH Apponi, SW Leung, KR Williams, SR Valentini, AH Corbett, GK Pavlath
Human molecular genetics 19 (6), 1058-1065, 2010
Actively transcribed GAL genes can be physically linked to the nuclear pore by the SAGA chromatin modifying complex
R Luthra, SC Kerr, MT Harreman, LH Apponi, MB Fasken, S Ramineni, ...
Journal of Biological Chemistry 282 (5), 3042-3049, 2007
PABPN 1: molecular function and muscle disease
A Banerjee, LH Apponi, GK Pavlath, AH Corbett
The FEBS journal 280 (17), 4230-4250, 2013
Mutation of the conserved polyadenosine RNA binding protein, ZC3H14/dNab2, impairs neural function in Drosophila and humans
CH Pak, M Garshasbi, K Kahrizi, C Gross, LH Apponi, JJ Noto, SM Kelly, ...
Proceedings of the National Academy of Sciences 108 (30), 12390-12395, 2011
RNA-binding proteins and gene regulation in myogenesis
LH Apponi, AH Corbett, GK Pavlath
Trends in pharmacological sciences 32 (11), 652-658, 2011
Inhibition of glycolate oxidase with dicer-substrate siRNA reduces calcium oxalate deposition in a mouse model of primary hyperoxaluria type 1
C Dutta, N Avitahl-Curtis, N Pursell, ML Cohen, B Holmes, R Diwanji, ...
Molecular Therapy 24 (4), 770-778, 2016
H2B ubiquitylation controls the formation of export-competent mRNP
A Vitaliano-Prunier, A Babour, L Hérissant, L Apponi, T Margaritis, ...
Molecular cell 45 (1), 132-139, 2012
Structural modeling and mutational analysis of yeast eukaryotic translation initiation factor 5A reveal new critical residues and reinforce its involvement in protein synthesis
CAO Dias, VSP Cano, SM Rangel, LH Apponi, MC Frigieri, JRC Muniz, ...
The FEBS journal 275 (8), 1874-1888, 2008
The mitogen-activated protein kinase Slt2 regulates nuclear retention of non-heat shock mRNAs during heat shock-induced stress
SR Carmody, EJ Tran, LH Apponi, AH Corbett, SR Wente
Molecular and Cellular Biology 30 (21), 5168-5179, 2010
Recognition of polyadenosine RNA by the zinc finger domain of nuclear poly (A) RNA-binding protein 2 (Nab2) is required for correct mRNA 3′-end formation
SM Kelly, SW Leung, LH Apponi, AM Bramley, EJ Tran, JA Chekanova, ...
Journal of biological chemistry 285 (34), 26022-26032, 2010
Splice variants of the human ZC3H14 gene generate multiple isoforms of a zinc finger polyadenosine RNA binding protein
SW Leung, LH Apponi, OE Cornejo, CM Kitchen, SR Valentini, ...
Gene 439 (1-2), 71-78, 2009
Expression of the Interleukin‐10 signaling pathway genes in individuals with down syndrome and periodontitis
LB Cavalcante, MH Tanaka, JR Pires, L Henrique Apponi, ...
Journal of periodontology 83 (7), 926-935, 2012
Endogenous ADAR-mediated RNA editing in non-human primates using stereopure chemically modified oligonucleotides
P Monian, C Shivalila, G Lu, M Shimizu, D Boulay, K Bussow, M Byrne, ...
Nature Biotechnology 40 (7), 1093-1102, 2022
Novel mouse models of oculopharyngeal muscular dystrophy (OPMD) reveal early onset mitochondrial defects and suggest loss of PABPN1 may contribute to pathology
KE Vest, BL Phillips, A Banerjee, LH Apponi, EB Dammer, W Xu, D Zheng, ...
Human molecular genetics 26 (17), 3235-3252, 2017
Control of mRNA stability contributes to low levels of nuclear poly (A) binding protein 1 (PABPN1) in skeletal muscle
LH Apponi, AH Corbett, GK Pavlath
Skeletal muscle 3, 1-9, 2013
Expression of interferon-γ, interferon-α and related genes in individuals with Down syndrome and periodontitis
MH Tanaka, EMA Giro, LB Cavalcante, JR Pires, LH Apponi, SR Valentini, ...
Cytokine 60 (3), 875-881, 2012
An interaction between two RNA binding proteins, Nab2 and Pub1, links mRNA processing/export and mRNA stability
LH Apponi, SM Kelly, MT Harreman, AN Lehner, AH Corbett, SR Valentini
Molecular and cellular biology, 2007
Synthetic lethality between eIF5A and Ypt1 reveals a connection between translation and the secretory pathway in yeast
MC Frigieri, MVS João Luiz, LH Apponi, CF Zanelli, SR Valentini
Molecular Genetics and Genomics 280, 211-221, 2008
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