Thomas Look

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Donna NeubergDana-Farber Cancer InstituteVerified email at jimmy.harvard.edu
John M MarisProfessor Pediatrics, Children's Hospital of Philadelphia and University of PennsylvaniaVerified email at chop.edu
Shuning HeDana-Farber Cancer InstituteVerified email at dfci.harvard.edu
Richard YoungProfessor of Biology, MITVerified email at wi.mit.edu
Alejandro GutierrezBoston Children's HospitalVerified email at childrens.harvard.edu
Adam DurbinAssistant Member, Department of Oncology, St. Jude Children's Research HospitalVerified email at stjude.org
Linda H. ShapiroUniversity of Connecticut School of MedicineVerified email at uchc.edu
Hui FengBoston UniversityVerified email at bu.edu
Andrew Philip WengTerry Fox Laboratory and Department of Pathology, British Columbia Cancer AgencyVerified email at bccrc.ca
Mignon LohProfessor of Pediatrics, UCSFVerified email at ucsf.edu
Teresa PalomeroProfessor of Pathology and Cell Biology at CUMCVerified email at cumc.columbia.edu
David TraverProfessor of Cellular and Molecular MedicineVerified email at ucsd.edu
Alex KentsisTow Center for Developmental Oncology, Memorial Sloan Kettering Cancer CenterVerified email at mskcc.org
Michael BorowitzJohns Hopkins Medical InsitutionsVerified email at jhmi.edu
Scott RodigProfessor of Pathology, Brigham & Women's HospitalVerified email at bwh.harvard.edu
Suzanne DahlbergAssociate Professor, Harvard Medical School, Boston Children's HospitalVerified email at childrens.harvard.edu
Catriona JamiesonProfessor of Medicine and Chief, Division of Regenerative Medicine, UC San DiegoVerified email at ucsd.edu
Zhaodong Li, Ph.D.DFCI, Harvard Medical SchoolVerified email at dfci.harvard.edu
Stephen HungerChildren's Hospital of PhiladelphiaVerified email at email.chop.edu
Yi ZhouHarvard Medical School Boston Children's HospitalVerified email at enders.tch.harvard.edu

Thomas Look

Professor of Pediatrics, Harvard Medical School

Verified email at dfci.harvard.edu - Homepage

Cancer research


Title Sort by citations Sort by year Sort by title	Cited by Cited by	Year
Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia AP Weng, AA Ferrando, W Lee, JP Morris IV, LB Silverman, ... Science 306 (5694), 269-271, 2004	3424	2004
Fusion of a kinase gene, ALK, to a nucleolar protein gene, NPM, in non-Hodgkin's lymphoma SW Morris, MN Kirstein, MB Valentine, KG Dittmer, DN Shapiro, ... Science 263 (5151), 1281-1284, 1994	2831	1994
Acute lymphoblastic leukaemia CH Pui, LL Robison, AT Look The Lancet 371 (9617), 1030-1043, 2008	2315	2008
The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF 1 CJ Sherr, CW Rettenmier, R Sacca, MF Roussel, AT Look, ER Stanley Cell 41 (3), 665-676, 1985	1885	1985
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish P Niethammer, C Grabher, AT Look, TJ Mitchison Nature 459 (7249), 996-999, 2009	1775	2009
Oncogenic transcription factors in the human acute leukemias AT Look Science 278 (5340), 1059-1064, 1997	1525	1997
Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia AA Ferrando, DS Neuberg, J Staunton, ML Loh, C Huard, SC Raimondi, ... Cancer cell 1 (1), 75-87, 2002	1338	2002
Human aminopeptidase N is a receptor for human coronavirus 229E CL Yeager, RA Ashmun, RK Williams, CB Cardellichio, LH Shapiro, ... Nature 357 (6377), 420-422, 1992	1181	1992
NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth T Palomero, WK Lim, DT Odom, ML Sulis, PJ Real, A Margolin, ... Proceedings of the National Academy of Sciences 103 (48), 18261-18266, 2006	1057	2006
Activating mutations in ALK provide a therapeutic target in neuroblastoma RE George, T Sanda, M Hanna, S Fröhling, WL Ii, J Zhang, Y Ahn, ... Nature 455 (7215), 975-978, 2008	1038	2008
Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN T Teitz, T Wei, MB Valentine, EF Vanin, J Grenet, VA Valentine, FG Behm, ... Nature medicine 6 (5), 529-535, 2000	1019	2000
An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element MR Mansour, BJ Abraham, L Anders, A Berezovskaya, A Gutierrez, ... Science 346 (6215), 1373-1377, 2014	896	2014
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors J O'Neil, J Grim, P Strack, S Rao, D Tibbitts, C Winter, J Hardwick, ... The Journal of experimental medicine 204 (8), 1813-1824, 2007	811	2007
BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma EE Patton, HR Widlund, JL Kutok, KR Kopani, JF Amatruda, RD Murphey, ... Current Biology 15 (3), 249-254, 2005	779	2005
Identification of breakpoints in t (8; 21) acute myelogenous leukemia and isolation of a fusion transcript, AML1/ETO, with similarity to Drosophila segmentation gene, runt P Erickson, J Gao, KS Chang, T Look, E Whisenant, S Raimondi, ...	769	1992
Chromosome 1p and 11q deletions and outcome in neuroblastoma EF Attiyeh, WB London, YP Mossé, Q Wang, C Winter, D Khazi, ... New England Journal of Medicine 353 (21), 2243-2253, 2005	755	2005
The use of zebrafish to understand immunity NS Trede, DM Langenau, D Traver, AT Look, LI Zon Immunity 20 (4), 367-379, 2004	752	2004
Clinical relevance of tumor cell ploidy and N-myc gene amplification in childhood neuroblastoma: a Pediatric Oncology Group study. AT Look, FA Hayes, JJ Shuster, EC Douglass, RP Castleberry, ... Journal of Clinical Oncology 9 (4), 581-591, 1991	748	1991
Evidence for an age cutoff greater than 365 days for neuroblastoma risk group stratification in the Children's Oncology Group WB London, RP Castleberry, KK Matthay, AT Look, RC Seeger, ... Journal of clinical oncology 23 (27), 6459-6465, 2005	712	2005
tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors S Berghmans, RD Murphey, E Wienholds, D Neuberg, JL Kutok, ... Proceedings of the National Academy of Sciences 102 (2), 407-412, 2005	709	2005

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