The inhibitory cytokine IL-35 contributes to regulatory T-cell function LW Collison, CJ Workman, TT Kuo, K Boyd, Y Wang, KM Vignali, R Cross, ... Nature 450 (7169), 566-569, 2007 | 2819 | 2007 |
Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide–based retroviral vector AL Szymczak, CJ Workman, Y Wang, KM Vignali, S Dilioglou, EF Vanin, ... Nature biotechnology 22 (5), 589-594, 2004 | 1508 | 2004 |
The composition and signaling of the IL-35 receptor are unconventional LW Collison, GM Delgoffe, CS Guy, KM Vignali, V Chaturvedi, ... Nature immunology 13 (3), 290-299, 2012 | 547 | 2012 |
Generation of T-cell receptor retrogenic mice J Holst, AL Szymczak-Workman, KM Vignali, AR Burton, CJ Workman, ... Nature protocols 1 (1), 406-417, 2006 | 337 | 2006 |
Metalloproteases regulate T‐cell proliferation and effector function via LAG‐3 N Li, Y Wang, K Forbes, KM Vignali, BS Heale, P Saftig, D Hartmann, ... The EMBO journal 26 (2), 494-504, 2007 | 306 | 2007 |
Design and construction of 2A peptide-linked multicistronic vectors AL Szymczak-Workman, KM Vignali, DAA Vignali Cold Spring Harbor Protocols 2012 (2), pdb. ip067876, 2012 | 302 | 2012 |
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells CS Guy, KM Vignali, J Temirov, ML Bettini, AE Overacre, M Smeltzer, ... Nature immunology 14 (3), 262-270, 2013 | 278 | 2013 |
Treg cells promote the SREBP1-dependent metabolic fitness of tumor-promoting macrophages via repression of CD8+ T cell-derived interferon-γ C Liu, M Chikina, R Deshpande, AV Menk, T Wang, T Tabib, EA Brunazzi, ... Immunity 51 (2), 381-397. e6, 2019 | 276 | 2019 |
T cell receptor recognition of MHC class II–bound peptide flanking residues enhances immunogenicity and results in altered TCR V region usage RT Carson, KM Vignali, DL Woodland, DAA Vignali Immunity 7 (3), 387-399, 1997 | 217 | 1997 |
Rapid analysis of T-cell selection in vivo using T cell–receptor retrogenic mice J Holst, KM Vignali, AR Burton, DAA Vignali Nature methods 3 (3), 191-197, 2006 | 196 | 2006 |
The majority of immunogenic epitopes generate CD4+ T cells that are dependent on MHC class II-bound peptide-flanking residues PY Arnold, NL La Gruta, T Miller, KM Vignali, PS Adams, DL Woodland, ... The Journal of Immunology 169 (2), 739-749, 2002 | 166 | 2002 |
LAG3 limits regulatory T cell proliferation and function in autoimmune diabetes Q Zhang, M Chikina, AL Szymczak-Workman, W Horne, JK Kolls, ... Science immunology 2 (9), eaah4569, 2017 | 159 | 2017 |
LAG3 associates with TCR–CD3 complexes and suppresses signaling by driving co-receptor–Lck dissociation C Guy, DM Mitrea, PC Chou, J Temirov, KM Vignali, X Liu, H Zhang, ... Nature immunology 23 (5), 757-767, 2022 | 133 | 2022 |
Cutting edge: virus-specific CD4+ memory T cells in nonlymphoid tissues express a highly activated phenotype LS Cauley, T Cookenham, TB Miller, PS Adams, KM Vignali, DAA Vignali, ... The Journal of Immunology 169 (12), 6655-6658, 2002 | 114 | 2002 |
Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity C Liu, A Somasundaram, S Manne, AM Gocher, AL Szymczak-Workman, ... Nature immunology 21 (9), 1010-1021, 2020 | 113 | 2020 |
The CD3ε proline-rich sequence, and its interaction with Nck, is not required for T cell development and function AL Szymczak, CJ Workman, D Gil, S Dilioglou, KM Vignali, E Palmer, ... The Journal of Immunology 175 (1), 270-275, 2005 | 93 | 2005 |
Profound enhancement of T cell activation mediated by the interaction between the TCR and the D3 domain of CD4 DAA Vignali, KM Vignali The Journal of Immunology 162 (3), 1431-1439, 1999 | 75 | 1999 |
Cutting edge: CD3 ITAM diversity is required for optimal TCR signaling and thymocyte development ML Bettini, PC Chou, CS Guy, T Lee, KM Vignali, DAA Vignali The Journal of Immunology 199 (5), 1555-1560, 2017 | 47 | 2017 |
Identification of the docking site for CD3 on the T cell receptor β chain by solution NMR Y He, S Rangarajan, M Kerzic, M Luo, Y Chen, Q Wang, Y Yin, ... Journal of Biological Chemistry 290 (32), 19796-19805, 2015 | 45 | 2015 |
Membrane association of the CD3ε signaling domain is required for optimal T cell development and function ML Bettini, C Guy, P Dash, KM Vignali, DE Hamm, J Dobbins, E Gagnon, ... The Journal of Immunology 193 (1), 258-267, 2014 | 45 | 2014 |