| Glucose depletion rapidly inhibits translation initiation in yeast MP Ashe, SK De Long, AB Sachs Molecular biology of the cell 11 (3), 833-848, 2000 | 485 | 2000 |
| Global translational responses to oxidative stress impact upon multiple levels of protein synthesis D Shenton, JB Smirnova, JN Selley, K Carroll, SJ Hubbard, GD Pavitt, ... Journal of Biological Chemistry 281 (39), 29011-29021, 2006 | 459 | 2006 |
| Stress-dependent relocalization of translationally primed mRNPs to cytoplasmic granules that are kinetically and spatially distinct from P-bodies NP Hoyle, LM Castelli, SG Campbell, LEA Holmes, MP Ashe The Journal of cell biology 179 (1), 65-74, 2007 | 273 | 2007 |
| The yeast poly (A)-binding protein Pab1p stimulates in vitro poly (A)-dependent and cap-dependent translation by distinct mechanisms LJ Otero, MP Ashe, AB Sachs The EMBO journal 18 (11), 3153-3163, 1999 | 172 | 1999 |
| The HIV-1 5′ LTR poly (A) site is inactivated by U1 snRNP interaction with the downstream major splice donor site MP Ashe, LH Pearson, NJ Proudfoot The EMBO journal 16 (18), 5752-5763, 1997 | 163 | 1997 |
| Poly (A) site selection in the HIV-1 provirus: inhibition of promoter-proximal polyadenylation by the downstream major splice donor site. MP Ashe, P Griffin, W James, NJ Proudfoot Genes & development 9 (23), 3008-3025, 1995 | 156 | 1995 |
| Gcn4 Is Required for the Response to Peroxide Stress in the Yeast Saccharomyces cerevisiae C Mascarenhas, LC Edwards-Ingram, L Zeef, D Shenton, MP Ashe, ... Molecular biology of the cell 19 (7), 2995-3007, 2008 | 136 | 2008 |
| Global gene expression profiling reveals widespread yet distinctive translational responses to different eukaryotic translation initiation factor 2B-targeting stress pathways JB Smirnova, JN Selley, F Sanchez-Cabo, K Carroll, AA Eddy, ... Molecular and cellular biology 25 (21), 9340-9349, 2005 | 124 | 2005 |
| A novel eIF2B-dependent mechanism of translational control in yeast as a response to fusel alcohols MP Ashe, JW Slaven, K Susan, S Ibrahimo, AB Sachs The EMBO journal 20 (22), 6464-6474, 2001 | 109 | 2001 |
| Loss of translational control in yeast compromised for the major mRNA decay pathway LEA Holmes, SG Campbell, SK De Long, AB Sachs, MP Ashe Molecular and cellular biology, 2004 | 106 | 2004 |
| TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectors JR Rohde, S Campbell, SA Zurita-Martinez, NS Cutler, M Ashe, ... Molecular and cellular biology 24 (19), 8332-8341, 2004 | 105 | 2004 |
| Upstream sequence elements direct post-transcriptional regulation of gene expression under stress conditions in yeast C Lawless, RD Pearson, JN Selley, JB Smirnova, CM Grant, MP Ashe, ... BMC genomics 10, 1-20, 2009 | 104 | 2009 |
| Global mRNA selection mechanisms for translation initiation J Costello, LM Castelli, W Rowe, CJ Kershaw, D Talavera, ... Genome biology 16 (1), 1-21, 2015 | 100 | 2015 |
| Glucose depletion inhibits translation initiation via eIF4A loss and subsequent 48S preinitiation complex accumulation, while the pentose phosphate pathway is coordinately up … LM Castelli, J Lui, SG Campbell, W Rowe, LAH Zeef, LEA Holmes, ... Molecular biology of the cell 22 (18), 3379-3393, 2011 | 96 | 2011 |
| Adaptation to stress in yeast: to translate or not? CE Simpson, MP Ashe Biochemical Society Transactions 40 (4), 794-799, 2012 | 91 | 2012 |
| Dynamic cycling of eIF2 through a large eIF2B-containing cytoplasmic body: implications for translation control SG Campbell, NP Hoyle, MP Ashe The Journal of cell biology 170 (6), 925-934, 2005 | 88 | 2005 |
| Stem-loop 1 of the U1 snRNP plays a critical role in the suppression of HIV-1 polyadenylation. MP Ashe, A Furger, NJ Proudfoot Rna 6 (2), 170-177, 2000 | 88 | 2000 |
| The mTOR-S6 kinase pathway promotes stress granule assembly AP Sfakianos, LE Mellor, YF Pang, P Kritsiligkou, H Needs, ... Cell Death & Differentiation 25 (10), 1766-1780, 2018 | 72 | 2018 |
| Granules harboring translationally active mRNAs provide a platform for P-body formation following stress J Lui, LM Castelli, M Pizzinga, CE Simpson, NP Hoyle, KL Bailey, ... Cell reports 9 (3), 944-954, 2014 | 68 | 2014 |
| Identifying eIF4E-binding protein translationally-controlled transcripts reveals links to mRNAs bound by specific PUF proteins AG Cridge, LM Castelli, JB Smirnova, JN Selley, W Rowe, SJ Hubbard, ... Nucleic acids research 38 (22), 8039-8050, 2010 | 64 | 2010 |
Chris GrantProfessor of Biochemistry, University of ManchesterVerified email at manchester.ac.uk
