Gal Bitan
Gal Bitan
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Amyloid β-protein (Aβ) assembly: Aβ40 and Aβ42 oligomerize through distinct pathways
G Bitan, MD Kirkitadze, A Lomakin, SS Vollers, GB Benedek, DB Teplow
Proceedings of the National Academy of Sciences 100 (1), 330-335, 2003
Amyloid-β protein oligomerization and the importance of tetramers and dodecamers in the aetiology of Alzheimer's disease
SL Bernstein, NF Dupuis, ND Lazo, T Wyttenbach, MM Condron, G Bitan, ...
Nature chemistry 1 (4), 326-331, 2009
Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: the emerging role of oligomeric assemblies
MD Kirkitadze, G Bitan, DB Teplow
Journal of neuroscience research 69 (5), 567-577, 2002
Amyloid β-protein oligomerization: prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins
G Bitan, A Lomakin, DB Teplow
Journal of Biological Chemistry 276 (37), 35176-35184, 2001
Increased T cell reactivity to amyloid β protein in older humans and patients with Alzheimer disease
A Monsonego, V Zota, A Karni, JI Krieger, A Bar-Or, G Bitan, AE Budson, ...
The Journal of clinical investigation 112 (3), 415-422, 2003
In silico study of amyloid β-protein folding and oligomerization
B Urbanc, L Cruz, S Yun, SV Buldyrev, G Bitan, DB Teplow, HE Stanley
Proceedings of the National Academy of Sciences 101 (50), 17345-17350, 2004
Amyloid β-protein: monomer structure and early aggregation states of Aβ42 and its Pro19 alloform
SL Bernstein, T Wyttenbach, A Baumketner, JE Shea, G Bitan, DB Teplow, ...
Journal of the American Chemical Society 127 (7), 2075-2084, 2005
Elucidation of primary structure elements controlling early amyloid β-protein oligomerization
G Bitan, SS Vollers, DB Teplow
Journal of Biological Chemistry 278 (37), 34882-34889, 2003
Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins
S Sinha, DHJ Lopes, Z Du, ES Pang, A Shanmugam, A Lomakin, ...
Journal of the American Chemical Society 133 (42), 16958-16969, 2011
Amyloid β‐protein monomer structure: A computational and experimental study
A Baumketner, SL Bernstein, T Wyttenbach, G Bitan, DB Teplow, ...
Protein Science 15 (3), 420-428, 2006
Neurotoxic protein oligomers—what you see is not always what you get
G Bitan, EA Fradinger, SM Spring, DB Teplow
Amyloid 12 (2), 88-95, 2005
Elucidation of amyloid β-protein oligomerization mechanisms: discrete molecular dynamics study
B Urbanc, M Betnel, L Cruz, G Bitan, DB Teplow
Journal of the American Chemical Society 132 (12), 4266-4280, 2010
Elucidating amyloid β-protein folding and assembly: a multidisciplinary approach
DB Teplow, ND Lazo, G Bitan, S Bernstein, T Wyttenbach, MT Bowers, ...
Accounts of chemical research 39 (9), 635-645, 2006
Rapid photochemical cross-linking a new tool for studies of metastable, amyloidogenic protein assemblies
G Bitan, DB Teplow
Accounts of chemical research 37 (6), 357-364, 2004
A molecular switch in amyloid assembly: Met35 and amyloid β-protein oligomerization
G Bitan, B Tarus, SS Vollers, HA Lashuel, MM Condron, JE Straub, ...
Journal of the American Chemical Society 125 (50), 15359-15365, 2003
C-terminal peptides coassemble into Aβ42 oligomers and protect neurons against Aβ42-induced neurotoxicity
EA Fradinger, BH Monien, B Urbanc, A Lomakin, M Tan, H Li, SM Spring, ...
Proceedings of the National Academy of Sciences 105 (37), 14175-14180, 2008
A Novel “Molecular Tweezer” Inhibitor of α-Synuclein Neurotoxicity in Vitro and in Vivo
S Prabhudesai, S Sinha, A Attar, A Kotagiri, AG Fitzmaurice, ...
Neurotherapeutics 9, 464-476, 2012
CNS-derived blood exosomes as a promising source of biomarkers: opportunities and challenges
S Hornung, S Dutta, G Bitan
Frontiers in Molecular Neuroscience 13, 38, 2020
Role of electrostatic interactions in amyloid β-protein (Aβ) oligomer formation: a discrete molecular dynamics study
S Yun, B Urbanc, L Cruz, G Bitan, DB Teplow, HE Stanley
Biophysical journal 92 (11), 4064-4077, 2007
A shortened Barnes maze protocol reveals memory deficits at 4-months of age in the triple-transgenic mouse model of Alzheimer's disease
A Attar, T Liu, WTC Chan, J Hayes, M Nejad, KC Lei, G Bitan
PloS one 8 (11), e80355, 2013
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