Kirti Sharma
Kirti Sharma
Senior Director, Kymera Therapeutics, Cambridge, MA 02139
Verified email at - Homepage
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Ultradeep human phosphoproteome reveals a distinct regulatory nature of Tyr and Ser/Thr-based signaling
K Sharma, RCJ D’Souza, S Tyanova, C Schaab, JR Wiśniewski, J Cox, ...
Cell reports 8 (5), 1583-1594, 2014
Cell type–and brain region–resolved mouse brain proteome
K Sharma, S Schmitt, CG Bergner, S Tyanova, N Kannaiyan, ...
Nature neuroscience 18 (12), 1819-1831, 2015
Inflammatory signaling in human tuberculosis granulomas is spatially organized
MJ Marakalala, RM Raju, K Sharma, YJ Zhang, EA Eugenin, B Prideaux, ...
Nature medicine 22 (5), 531-538, 2016
AXL is a potential target for therapeutic intervention in breast cancer progression
YX Zhang, PG Knyazev, YV Cheburkin, K Sharma, YP Knyazev, L Orfi, ...
Cancer research 68 (6), 1905-1915, 2008
Large-scale phosphosite quantification in tissues by a spike-in SILAC method
M Monetti, N Nagaraj, K Sharma, M Mann
Nature methods 8 (8), 655-658, 2011
Proteomics strategy for quantitative protein interaction profiling in cell extracts
K Sharma, C Weber, M Bairlein, Z Greff, G Kéri, J Cox, JV Olsen, H Daub
Nature methods 6 (10), 741-744, 2009
Transcriptional Control of the Mycobacterial embCAB Operon by PknH through a Regulatory Protein, EmbR, In Vivo
K Sharma, M Gupta, M Pathak, N Gupta, A Koul, S Sarangi, R Baweja, ...
Journal of bacteriology 188 (8), 2936-2944, 2006
Quantitative proteomics reveals that Hsp90 inhibition preferentially targets kinases and the DNA damage response
K Sharma, RM Vabulas, B Macek, S Pinkert, J Cox, M Mann, FU Hartl
Molecular & cellular proteomics 11 (3), 2012
Serine threonine protein kinases of mycobacterial genus: phylogeny to function
A Narayan, P Sachdeva, K Sharma, AK Saini, AK Tyagi, Y Singh
Physiological genomics 29 (1), 66-75, 2007
In vivo brain GPCR signaling elucidated by phosphoproteomics
JJ Liu, K Sharma, L Zangrandi, C Chen, SJ Humphrey, YT Chiu, M Spetea, ...
Science 360 (6395), eaao4927, 2018
Handbook of systems biology: concepts and insights
M Walhout, M Vidal, J Dekker
Academic Press, 2012
EmbR, a regulatory protein with ATPase activity, is a substrate of multiple serine/threonine kinases and phosphatase in Mycobacterium tuberculosis
K Sharma, M Gupta, A Krupa, N Srinivasan, Y Singh
The FEBS journal 273 (12), 2711-2721, 2006
HupB, a Nucleoid-Associated Protein of Mycobacterium tuberculosis, Is Modified by Serine/Threonine Protein Kinases In Vivo
M Gupta, A Sajid, K Sharma, S Ghosh, G Arora, R Singh, V Nagaraja, ...
Journal of bacteriology 196 (14), 2646-2657, 2014
Properties of Bacillus anthracis spores prepared under various environmental conditions
RB Baweja, MS Zaman, AR Mattoo, K Sharma, V Tripathi, A Aggarwal, ...
Archives of Microbiology 189, 71-79, 2008
Regulation of liver metabolism by the endosomal GTPase Rab5
A Zeigerer, RL Bogorad, K Sharma, J Gilleron, S Seifert, S Sales, ...
Cell reports 11 (6), 884-892, 2015
Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β
RC J. D’Souza, AM Knittle, N Nagaraj, M van Dinther, C Choudhary, ...
Science signaling 7 (335), rs5-rs5, 2014
PknH, a transmembrane Hank's type serine/threonine kinase from Mycobacterium tuberculosis is differentially expressed under stress conditions
K Sharma, H Chandra, PK Gupta, M Pathak, A Narayan, LS Meena, ...
FEMS microbiology letters 233 (1), 107-113, 2004
Proteome analysis of mouse macrophages treated with anthrax lethal toxin
H Chandra, PK Gupta, K Sharma, AR Mattoo, SK Garg, WN Gade, ...
Biochimica et Biophysica Acta (BBA)-Proteins & Proteomics 1747 (2), 151-159, 2005
Quantitative analysis of kinase-proximal signaling in lipopolysaccharide-induced innate immune response
K Sharma, C Kumar, G Kéri, SB Breitkopf, FS Oppermann, H Daub
Journal of proteome research 9 (5), 2539-2549, 2010
Recent advances towards identification of new drug targets for Mycobacterium tuberculosis
K Sharma, P Chopra, Y Singh
Expert Opinion on Therapeutic Targets 8 (2), 79-93, 2004
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