Jana Zecha
Jana Zecha
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The target landscape of clinical kinase drugs
S Klaeger, S Heinzlmeir, M Wilhelm, H Polzer, B Vick, PA Koenig, ...
Science 358 (6367), eaan4368, 2017
A deep proteome and transcriptome abundance atlas of 29 healthy human tissues
D Wang, B Eraslan, T Wieland, B Hallström, T Hopf, DP Zolg, J Zecha, ...
Molecular systems biology 15 (2), e8503, 2019
TMT Labeling for the Masses: A Robust and Cost-efficient, In-solution Labeling Approach
J Zecha, S Satpathy, T Kanashova, SC Avanessian, MH Kane, ...
Molecular & cellular proteomics 18 (7), 1468-1478, 2019
Robust, reproducible and quantitative analysis of thousands of proteomes by micro-flow LC–MS/MS
Y Bian, R Zheng, FP Bayer, C Wong, YC Chang, C Meng, DP Zolg, ...
Nature communications 11 (1), 157, 2020
ProteomicsDB: a multi-omics and multi-organism resource for life science research
P Samaras, T Schmidt, M Frejno, S Gessulat, M Reinecke, A Jarzab, ...
Nucleic acids research 48 (D1), D1153-D1163, 2020
Meltome atlas—thermal proteome stability across the tree of life
A Jarzab, N Kurzawa, T Hopf, M Moerch, J Zecha, N Leijten, Y Bian, ...
Nature methods 17 (5), 495-503, 2020
Peptide level turnover measurements enable the study of proteoform dynamics
J Zecha, C Meng, DP Zolg, P Samaras, M Wilhelm, B Kuster
Molecular & Cellular Proteomics 17 (5), 974-992, 2018
Lapatinib resistance in breast cancer cells is accompanied by phosphorylation-mediated reprogramming of glycolysis
B Ruprecht, EA Zaal, J Zecha, W Wu, CR Berkers, B Kuster, S Lemeer
Cancer research 77 (8), 1842-1853, 2017
Data, reagents, assays and merits of proteomics for SARS-CoV-2 research and testing
J Zecha, CY Lee, FP Bayer, C Meng, V Grass, J Zerweck, K Schnatbaum, ...
Molecular & Cellular Proteomics 19 (9), 1503-1522, 2020
Proteome activity landscapes of tumor cell lines determine drug responses
M Frejno, C Meng, B Ruprecht, T Oellerich, S Scheich, K Kleigrewe, ...
Nature communications 11 (1), 3639, 2020
Linking post-translational modifications and protein turnover by site-resolved protein turnover profiling
J Zecha, W Gabriel, R Spallek, YC Chang, J Mergner, M Wilhelm, ...
Nature communications 13 (1), 165, 2022
High pH reversed-phase micro-columns for simple, sensitive, and efficient fractionation of proteome and (TMT labeled) phosphoproteome digests
B Ruprecht, J Zecha, DP Zolg, B Kuster
Proteomics: Methods and Protocols, 83-98, 2017
Evaluation of kinase activity profiling using chemical proteomics
B Ruprecht, J Zecha, S Heinzlmeir, G Medard, S Lemeer, B Kuster
ACS chemical biology 10 (12), 2743-2752, 2015
The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma
M Heider, R Eichner, J Stroh, V Morath, A Kuisl, J Zecha, J Lawatscheck, ...
Molecular cell 81 (6), 1170-1186. e10, 2021
PTPN2 deficiency enhances programmed T cell expansion and survival capacity of activated T cells
M Flosbach, SG Oberle, S Scherer, J Zecha, M von Hoesslin, F Wiede, ...
Cell reports 32 (4), 2020
Decrypting drug actions and protein modifications by dose-and time-resolved proteomics
J Zecha, FP Bayer, S Wiechmann, J Woortman, N Berner, J Müller, ...
Science 380 (6640), 93-101, 2023
Functional expression of electrogenic sodium bicarbonate cotransporter 1 (NBCe1) in mouse cortical astrocytes is dependent on S255‐257 and regulated by mTOR
S Khakipoor, M Giannaki, SM Theparambil, J Zecha, B Küster, ...
Glia 67 (12), 2264-2278, 2019
A systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA and adenovirus vectored vaccines
FJ Ryan, TS Norton, C McCafferty, SJ Blake, NE Stevens, J James, ...
Cell Reports Medicine 4 (3), 2023
The OTUD6B‐LIN28B‐MYC axis determines the proliferative state in multiple myeloma
C Paulmann, R Spallek, O Karpiuk, M Heider, I Schäffer, J Zecha, ...
The EMBO Journal 41 (20), e110871, 2022
Multiomics Characterization of a Less Invasive Microfluidic-Based Cell Sorting Technique
FK Choudhury, V Premkumar, J Zecha, J Boyd, AS Gaynor, Z Guo, ...
Journal of Proteome Research, 2024
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