Linghui Qian
Linghui Qian
College of Pharmaceutical Sciences, Zhejiang University
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Tetrazole photoclick chemistry: reinvestigating its suitability as a bioorthogonal reaction and potential applications
Z Li, L Qian, L Li, JC Bernhammer, HV Huynh, JS Lee, SQ Yao
Angewandte Chemie International Edition 55 (6), 2002-2006, 2016
Two-photon small molecule enzymatic probes
L Qian, L Li, SQ Yao
Accounts of Chemical Research 49 (4), 626-634, 2016
Cell‐penetrating poly (disulfide) assisted intracellular delivery of mesoporous silica nanoparticles for inhibition of miR‐21 function and detection of subsequent therapeutic …
C Yu, L Qian, J Ge, J Fu, P Yuan, SCL Yao, SQ Yao
Angewandte Chemie International Edition 55 (32), 9272-9276, 2016
Intracellular delivery of native proteins facilitated by cell‐penetrating poly (disulfide) s
L Qian, J Fu, P Yuan, S Du, W Huang, L Li, SQ Yao
Angewandte Chemie 130 (6), 1548-1552, 2018
Intracellular delivery of functional native antibodies under hypoxic conditions by using a biodegradable silica nanoquencher
P Yuan, H Zhang, L Qian, X Mao, S Du, C Yu, B Peng, SQ Yao
Angewandte Chemie International Edition 56 (41), 12481-12485, 2017
A Small‐Molecule Probe for Selective Profiling and Imaging of Monoamine Oxidase B Activities in Models of Parkinson’s Disease
L Li, CW Zhang, J Ge, L Qian, BH Chai, Q Zhu, JS Lee, KL Lim, SQ Yao
Angewandte Chemie International Edition 54 (37), 10821-10825, 2015
Single‐vehicular delivery of antagomir and small molecules to inhibit miR‐122 function in hepatocellular carcinoma cells by using “smart” mesoporous silica nanoparticles
C Yu, L Qian, M Uttamchandani, L Li, SQ Yao
Angewandte Chemie International Edition 54 (36), 10574-10578, 2015
Red-emitting DPSB-based conjugated polymer nanoparticles with high two-photon brightness for cell membrane imaging
P Liu, S Li, Y Jin, L Qian, N Gao, SQ Yao, F Huang, QH Xu, Y Cao
ACS applied materials & interfaces 7 (12), 6754-6763, 2015
Recent advances in construction of small molecule-based fluorophore-drug conjugates
W Lang, C Yuan, L Zhu, S Du, L Qian, J Ge, SQ Yao
Journal of Pharmaceutical Analysis 10 (5), 434-443, 2020
The dawn of a new era: targeting the “undruggables” with antibody-based therapeutics
L Qian, X Lin, X Gao, RU Khan, JY Liao, S Du, J Ge, S Zeng, SQ Yao
Chemical reviews 123 (12), 7782-7853, 2023
Visualization of monoamine oxidases in living cells using “Turn-ON” fluorescence resonance energy transfer probes
X Li, J Yu, Q Zhu, L Qian, L Li, Y Zheng, SQ Yao
Analyst 139 (23), 6092-6095, 2014
Recent progress in the molecular imaging of therapeutic monoclonal antibodies
K He, S Zeng, L Qian
Journal of Pharmaceutical Analysis 10 (5), 397-413, 2020
Catalytic Atroposelective Dynamic Kinetic Resolution of Biaryl Lactones with Activated Isocyanides
L Qian, LF Tao, WT Wang, E Jameel, ZH Luo, T Zhang, Y Zhao, JY Liao
Organic Letters 23 (13), 5086-5091, 2021
Live-cell imaging and profiling of c-Jun N-terminal kinases using covalent inhibitor-derived probes
L Qian, S Pan, JS Lee, J Ge, L Li, SQ Yao
Chemical communications 55 (8), 1092-1095, 2019
Diastereo‐and Enantioselective Silver‐Catalyzed [3+ 3] Cycloaddition and Kinetic Resolution of Azomethine Imines with Activated Isocyanides
LF Tao, S Zhang, F Huang, WT Wang, ZH Luo, L Qian, JY Liao
Angewandte Chemie International Edition 61 (23), e202202679, 2022
Structure‐Based Specific Detection and Inhibition of Monoamine Oxidases and Their Applications in Central Nervous System Diseases
R Shi, Q Wu, C Xin, H Yu, KL Lim, X Li, Z Shi, CW Zhang, L Qian, L Li, ...
Chembiochem 20 (12), 1487-1497, 2019
Torsional Strain‐Independent Catalytic Enantioselective Synthesis of Biaryl Atropisomers
ZH Luo, WT Wang, TY Tang, S Zhang, F Huang, D Hu, LF Tao, L Qian, ...
Angewandte Chemie International Edition 61 (43), e202211303, 2022
Fused Bicyclic Caspase‐1 Inhibitors Assembled by Copper‐Free Strain‐Promoted Alkyne–Azide Cycloaddition (SPAAC)
L Qian, CJ Zhang, J Wu, SQ Yao
Chemistry–A European Journal 23 (2), 360-369, 2017
Two-photon enzymatic probes visualizing sub-cellular/deep-brain caspase activities in neurodegenerative models
L Qian, CW Zhang, Y Mao, L Li, N Gao, KL Lim, QH Xu, SQ Yao
Scientific reports 6 (1), 26385, 2016
Simultaneous Construction of C–N Axial and Central Chirality via Silver-Catalyzed Desymmetrizative [3+ 2] Cycloaddition of Prochiral N-Aryl Maleimides with Activated Isocyanides
S Zhang, ZH Luo, WT Wang, L Qian, JY Liao
Organic Letters 24 (25), 4645-4649, 2022
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