| The target landscape of clinical kinase drugs S Klaeger, S Heinzlmeir, M Wilhelm, H Polzer, B Vick, PA Koenig, ... Science 358 (6367), eaan4368, 2017 | 859 | 2017 |
| DMSO enhances electrospray response, boosting sensitivity of proteomic experiments H Hahne, F Pachl, B Ruprecht, SK Maier, S Klaeger, D Helm, G Médard, ... Nature methods 10 (10), 989-991, 2013 | 263 | 2013 |
| Optimized chemical proteomics assay for kinase inhibitor profiling G Médard, F Pachl, B Ruprecht, S Klaeger, S Heinzlmeir, D Helm, H Qiao, ... Journal of proteome research 14 (3), 1574-1586, 2015 | 154 | 2015 |
| Comprehensive and reproducible phosphopeptide enrichment using iron immobilized metal ion affinity chromatography (Fe-IMAC) columns B Ruprecht, H Koch, G Medard, M Mundt, B Kuster, S Lemeer Molecular & Cellular Proteomics 14 (1), 205-215, 2015 | 141 | 2015 |
| Ion mobility tandem mass spectrometry enhances performance of bottom-up proteomics D Helm, JPC Vissers, CJ Hughes, H Hahne, B Ruprecht, F Pachl, A Grzyb, ... Molecular & Cellular Proteomics 13 (12), 3709-3715, 2014 | 128 | 2014 |
| Lapatinib resistance in breast cancer cells is accompanied by phosphorylation-mediated reprogramming of glycolysis B Ruprecht, EA Zaal, J Zecha, W Wu, CR Berkers, B Kuster, S Lemeer Cancer research 77 (8), 1842-1853, 2017 | 113 | 2017 |
| A bead-based western for high-throughput cellular signal transduction analyses F Treindl, B Ruprecht, Y Beiter, S Schultz, A Döttinger, A Staebler, ... Nature communications 7 (1), 12852, 2016 | 112 | 2016 |
| Omomyc reveals new mechanisms to inhibit the MYC oncogene MJ Demma, C Mapelli, A Sun, S Bodea, B Ruprecht, S Javaid, D Wiswell, ... Molecular and cellular biology, 2019 | 86 | 2019 |
| Proteome activity landscapes of tumor cell lines determine drug responses M Frejno, C Meng, B Ruprecht, T Oellerich, S Scheich, K Kleigrewe, ... Nature communications 11 (1), 3639, 2020 | 72 | 2020 |
| Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry T Dixon, D MacPherson, B Mostofian, T Dauzhenka, S Lotz, D McGee, ... Nature communications 13 (1), 5884, 2022 | 67* | 2022 |
| Decrypting drug actions and protein modifications by dose-and time-resolved proteomics J Zecha, FP Bayer, S Wiechmann, J Woortman, N Berner, J Müller, ... Science 380 (6640), 93-101, 2023 | 64 | 2023 |
| Comparing immobilized kinase inhibitors and covalent ATP probes for proteomic profiling of kinase expression and drug selectivity S Lemeer, C Zörgiebel, B Ruprecht, K Kohl, B Kuster Journal of proteome research 12 (4), 1723-1731, 2013 | 62 | 2013 |
| Pharmacoproteomic characterisation of human colon and rectal cancer M Frejno, R Zenezini Chiozzi, M Wilhelm, H Koch, R Zheng, S Klaeger, ... Molecular systems biology 13 (11), 951, 2017 | 59 | 2017 |
| Chemical proteomics and structural biology define EPHA2 inhibition by clinical kinase drugs S Heinzlmeir, D Kudlinzki, S Sreeramulu, S Klaeger, SL Gande, V Linhard, ... ACS chemical biology 11 (12), 3400-3411, 2016 | 58 | 2016 |
| High pH reversed-phase micro-columns for simple, sensitive, and efficient fractionation of proteome and (TMT labeled) phosphoproteome digests B Ruprecht, J Zecha, DP Zolg, B Kuster Proteomics: Methods and Protocols, 83-98, 2017 | 52 | 2017 |
| A mass spectrometry-based proteome map of drug action in lung cancer cell lines B Ruprecht, J Di Bernardo, Z Wang, X Mo, O Ursu, M Christopher, ... Nature Chemical Biology 16 (10), 1111-1119, 2020 | 49 | 2020 |
| Proteomic analysis of phosphorylation in cancer B Ruprecht, S Lemeer Expert review of proteomics 11 (3), 259-267, 2014 | 49 | 2014 |
| Evaluation of kinase activity profiling using chemical proteomics B Ruprecht, J Zecha, S Heinzlmeir, G Medard, S Lemeer, B Kuster ACS chemical biology 10 (12), 2743-2752, 2015 | 43 | 2015 |
| Characterization of a chemical affinity probe targeting Akt kinases F Pachl, P Plattner, B Ruprecht, G Medard, N Sewald, B Kuster Journal of Proteome Research 12 (8), 3792-3800, 2013 | 41 | 2013 |
| Chemoproteomic selectivity profiling of PIKK and PI3K kinase inhibitors M Reinecke, B Ruprecht, S Poser, S Wiechmann, M Wilhelm, ... ACS chemical biology 14 (4), 655-664, 2019 | 35 | 2019 |
