Rene H. Medema
Rene H. Medema
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The β-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells
M Van de Wetering, E Sancho, C Verweij, W De Lau, I Oving, A Hurlstone, ...
Cell 111 (2), 241-250, 2002
AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1
RH Medema, GJPL Kops, JL Bos, BMT Burgering
Nature 404 (6779), 782-787, 2000
Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
GJPL Kops, TB Dansen, PE Polderman, I Saarloos, KWA Wirtz, PJ Coffer, ...
Nature 419 (6904), 316-321, 2002
Cell death by mitotic catastrophe: a molecular definition
M Castedo, JL Perfettini, T Roumier, K Andreau, R Medema, G Kroemer
Oncogene 23 (16), 2825-2837, 2004
Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1
PF Dijkers, RH Medema, JWJ Lammers, L Koenderman, PJ Coffer
Current Biology 10 (19), 1201-1204, 2000
FoxM1 is required for execution of the mitotic programme and chromosome stability
J Laoukili, MRH Kooistra, A Brás, J Kauw, RM Kerkhoven, A Morrison, ...
Nature cell biology 7 (2), 126-136, 2005
Forkhead Transcription Factor FKHR-L1 Modulates Cytokine-Dependent Transcriptional Regulation of p27KIP1
PF Dijkers, RH Medema, C Pals, L Banerji, NSB Thomas, EWF Lam, ...
Molecular and cellular biology 20 (24), 9138-9148, 2000
Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery
L Macůrek, A Lindqvist, D Lim, MA Lampson, R Klompmaker, R Freire, ...
Nature 455 (7209), 119-123, 2008
The forkhead transcription factor FoxO regulates transcription of p27Kip1 and Bim in response to IL-2
M Stahl, PF Dijkers, GJPL Kops, S Lens, PJ Coffer, BMT Burgering, ...
The Journal of Immunology 168 (10), 5024-5031, 2002
The decision to enter mitosis: feedback and redundancy in the mitotic entry network
A Lindqvist, V Rodríguez-Bravo, RH Medema
Journal of Cell Biology 185 (2), 193-202, 2009
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2SIRT1
A van der Horst, LGJ Tertoolen, LMM de Vries-Smits, RA Frye, ...
Journal of Biological Chemistry 279 (28), 28873-28879, 2004
Cell cycle inhibition by FoxO forkhead transcription factors involves downregulation of cyclin D
M Schmidt, SF de Mattos, A van der Horst, R Klompmaker, GJPL Kops, ...
Molecular and cellular biology, 2002
Shared and separate functions of polo-like kinases and aurora kinases in cancer
SMA Lens, EE Voest, RH Medema
Nature Reviews Cancer 10 (12), 825-841, 2010
Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrations
A Janssen, M Van Der Burg, K Szuhai, GJPL Kops, RH Medema
Science 333 (6051), 1895-1898, 2011
The cohesin release factor WAPL restricts chromatin loop extension
JHI Haarhuis, RH van der Weide, VA Blomen, JO Yáńez-Cuna, ...
Cell 169 (4), 693-707. e14, 2017
FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines
A Sunters, SF de Mattos, M Stahl, JJ Brosens, G Zoumpoulidou, ...
Journal of Biological Chemistry 278 (50), 49795-49805, 2003
Polo-like kinase-1 is a target of the DNA damage checkpoint
VAJ Smits, R Klompmaker, L Arnaud, G Rijksen, EA Nigg, RH Medema
Nature cell biology 2 (9), 672-676, 2000
FoxM1 promotes β-catenin nuclear localization and controls Wnt target-gene expression and glioma tumorigenesis
N Zhang, P Wei, A Gong, WT Chiu, HT Lee, H Colman, H Huang, J Xue, ...
Cancer cell 20 (4), 427-442, 2011
Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty
BMT Burgering, RH Medema
Journal of Leucocyte Biology 73 (6), 689-701, 2003
Growth suppression by p16ink4 requires functional retinoblastoma protein.
RH Medema, RE Herrera, F Lam, RA Weinberg
Proceedings of the National Academy of Sciences 92 (14), 6289-6293, 1995
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