Steffen Schmidt
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A method and server for predicting damaging missense mutations
IA Adzhubei, S Schmidt, L Peshkin, VE Ramensky, A Gerasimova, P Bork, ...
Nature methods 7 (4), 248-249, 2010
STRING: a database of predicted functional associations between proteins
C Mering, M Huynen, D Jaeggi, S Schmidt, P Bork, B Snel
Nucleic acids research 31 (1), 258-261, 2003
SMART 4.0: towards genomic data integration
I Letunic, RR Copley, S Schmidt, FD Ciccarelli, T Doerks, J Schultz, ...
Nucleic Acids Research 32 (suppl 1), D142-D144, 2004
Assessing the evolutionary impact of amino acid mutations in the human genome
AR Boyko, SH Williamson, AR Indap, JD Degenhardt, RD Hernandez, ...
PLoS Genet 4 (5), e1000083, 2008
Proportionally more deleterious genetic variation in European than in African populations
KE Lohmueller, AR Indap, S Schmidt, AR Boyko, RD Hernandez, ...
Nature 451 (7181), 994-997, 2008
Active Alu retrotransposons in the human genome
EA Bennett, H Keller, RE Mills, S Schmidt, JV Moran, O Weichenrieder, ...
Genome research 18 (12), 1875-1883, 2008
ProtGPT2 is a deep unsupervised language model for protein design
N Ferruz, S Schmidt, B Höcker
Nature communications 13 (1), 1-10, 2022
Medical sequencing at the extremes of human body mass
N Ahituv, N Kavaslar, W Schackwitz, A Ustaszewska, J Martin, S Hébert, ...
The American Journal of Human Genetics 80 (4), 779-791, 2007
Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival
N Wittkopp, E Huntzinger, C Weiler, J Saulière, S Schmidt, M Sonawane, ...
Molecular and cellular biology 29 (13), 3517-3528, 2009
Metabolites: a helping hand for pathway evolution?
S Schmidt, S Sunyaev, P Bork, T Dandekar
Trends in Biochemical Sciences 28 (6), 336-341, 2003
Small RNA binding to the lateral surface of Hfq hexamers and structural rearrangements upon mRNA target recognition
E Sauer, S Schmidt, O Weichenrieder
Proceedings of the National Academy of Sciences 109 (24), 9396-9401, 2012
Systematic discovery of analogous enzymes in thiamin biosynthesis
E Morett, JO Korbel, E Rajan, G Saab-Rincon, L Olvera, M Olvera, ...
Nature biotechnology 21 (7), 790-795, 2003
Trimeric structure and flexibility of the L1ORF1 protein in human L1 retrotransposition
E Khazina, V Truffault, R Büttner, S Schmidt, M Coles, O Weichenrieder
Nature structural & molecular biology 18 (9), 1006-1014, 2011
Crystal structure of the MID-PIWI lobe of a eukaryotic Argonaute protein
A Boland, E Huntzinger, S Schmidt, E Izaurralde, O Weichenrieder
Proceedings of the National Academy of Sciences 108 (26), 10466-10471, 2011
A limited role for balancing selection
S Asthana, S Schmidt, S Sunyaev
TRENDS in Genetics 21 (1), 30-32, 2005
The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4–NOT deadenylase complex
AP Petit, L Wohlbold, P Bawankar, E Huntzinger, S Schmidt, E Izaurralde, ...
Nucleic acids research 40 (21), 11058-11072, 2012
NOT10 and C2orf29/NOT11 form a conserved module of the CCR4-NOT complex that docks onto the NOT1 N-terminal domain
P Bawankar, B Loh, L Wohlbold, S Schmidt, E Izaurralde
RNA biology 10 (2), 228-244, 2013
Small fitness effect of mutations in highly conserved non-coding regions
GV Kryukov, S Schmidt, S Sunyaev
Human molecular genetics 14 (15), 2221-2229, 2005
Two (βα) 8-barrel enzymes of histidine and tryptophan biosynthesis have similar reaction mechanisms and common strategies for protecting their labile substrates
M Henn-Sax, R Thoma, S Schmidt, M Hennig, K Kirschner, R Sterner
Biochemistry 41 (40), 12032-12042, 2002
Similar modes of interaction enable Trailer Hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes
F Tritschler, A Eulalio, S Helms, S Schmidt, M Coles, O Weichenrieder, ...
Molecular and cellular biology 28 (21), 6695-6708, 2008
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