Juan-Jose Ventura
Juan-Jose Ventura
Associate Professor
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Mechanism of p38 MAP kinase activation in vivo
D Brancho, N Tanaka, A Jaeschke, JJ Ventura, N Kelkar, Y Tanaka, ...
Genes & development 17 (16), 1969-1978, 2003
Chemical genetic analysis of the time course of signal transduction by JNK
JJ Ventura, A Hübner, C Zhang, RA Flavell, KM Shokat, RJ Davis
Molecular cell 21 (5), 701-710, 2006
p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation
JJ Ventura, S Tenbaum, E Perdiguero, M Huth, C Guerra, M Barbacid, ...
Nature genetics 39 (6), 750-758, 2007
JNK potentiates TNF-stimulated necrosis by increasing the production of cytotoxic reactive oxygen species
JJ Ventura, P Cogswell, RA Flavell, AS Baldwin, RJ Davis
Genes & development 18 (23), 2905-2915, 2004
JunD mediates survival signaling by the JNK signal transduction pathway
JA Lamb, JJ Ventura, P Hess, RA Flavell, RJ Davis
Molecular cell 11 (6), 1479-1489, 2003
c-Jun NH2-terminal kinase is essential for the regulation of AP-1 by tumor necrosis factor
JJ Ventura, NJ Kennedy, JA Lamb, RA Flavell, RJ Davis
Molecular and cellular biology, 2003
JNK2 is a positive regulator of the cJun transcription factor
A Jaeschke, M Karasarides, JJ Ventura, A Ehrhardt, C Zhang, RA Flavell, ...
Molecular cell 23 (6), 899-911, 2006
Role of MLK3 in the regulation of mitogen-activated protein kinase signaling cascades
D Brancho, JJ Ventura, A Jaeschke, B Doran, RA Flavell, RJ Davis
Molecular and cellular biology 25 (9), 3670-3681, 2005
JNK regulates autocrine expression of TGF-β1
JJ Ventura, NJ Kennedy, RA Flavell, RJ Davis
Molecular cell 15 (2), 269-278, 2004
The death domain kinase RIP1 is essential for tumor necrosis factor alpha signaling to p38 mitogen-activated protein kinase
TH Lee, Q Huang, S Oikemus, J Shank, JJ Ventura, N Cusson, ...
Molecular and cellular biology, 2003
Protein kinases and phosphatases as therapeutic targets in cancer
JJ Ventura, ÁR Nebreda
Clinical and Translational Oncology 8 (3), 153-160, 2006
Regulation of human lung alveolar multipotent cells by a novel p38α MAPK/miR‐17‐92 axis
F Oeztuerk‐Winder, A Guinot, A Ochalek, JJ Ventura
The EMBO journal 31 (16), 3431-3441, 2012
EGF blocks NADPH oxidase activation by TGF‐β in fetal rat hepatocytes, impairing oxidative stress, and cell death
I Carmona‐Cuenca, B Herrera, JJ Ventura, C Roncero, M Fernández, ...
Journal of cellular physiology 207 (2), 322-330, 2006
Epidermal Growth Factor Impairs the Cytochrome C/Caspase-3 Apoptotic Pathway Induced by Transforming Growth Factor β in Rat Fetal Hepatocytes Via a Phosphoinositide 3-Kinase …
I Fabregat, B Herrera, M Fernández, AM Álvarez, A Sánchez, C Roncero, ...
Hepatology 32 (3), 528-535, 2000
p38 mitogen-activated protein kinase mediates tumor necrosis factor-α-induced apoptosis in rat fetal brown adipocytes
A Valladares, AM Álvarez, JJ Ventura, C Roncero, M Benito, A Porras
Endocrinology 141 (12), 4383-4395, 2000
The many faces of p38 mitogen-activated protein kinase in progenitor/stem cell differentiation
F Oeztuerk-Winder, JJ Ventura
Biochemical Journal 445 (1), 1-10, 2012
A paracrine network regulates the cross-talk between human lung stem cells and the stroma
EJ Ruiz, F Oeztuerk-Winder, JJ Ventura
Nature communications 5 (1), 3175, 2014
miR-17-92/p38α Dysregulation Enhances Wnt Signaling and Selects Lgr6+ Cancer Stem-like Cells during Lung Adenocarcinoma Progression
A Guinot, F Oeztuerk-Winder, JJ Ventura
Cancer research 76 (13), 4012-4022, 2016
Activation of p38MAPK by TGF-β in fetal rat hepatocytes requires radical oxygen production, but is dispensable for cell death
B Herrera, M Fernández, C Roncero, JJ Ventura, A Porras, A Valladares, ...
FEBS letters 499 (3), 225-229, 2001
C3G knock-down enhances migration and invasion by increasing Rap1-mediated p38α activation, while it impairs tumor growth through p38α-independent mechanisms
N Priego, M Arechederra, C Sequera, P Bragado, A Vázquez-Carballo, ...
Oncotarget 7 (29), 45060, 2016
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