| Drug-target interaction prediction from chemical, genomic and pharmacological data in an integrated framework Y Yamanishi, M Kotera, M Kanehisa, S Goto Bioinformatics 26 (12), i246-i254, 2010 | 526 | 2010 |
| PathPred: an enzyme-catalyzed metabolic pathway prediction server Y Moriya, D Shigemizu, M Hattori, T Tokimatsu, M Kotera, S Goto, ... Nucleic acids research 38 (suppl_2), W138-W143, 2010 | 283 | 2010 |
| Computational assignment of the EC numbers for genomic-scale analysis of enzymatic reactions M Kotera, Y Okuno, M Hattori, S Goto, M Kanehisa Journal of the American Chemical Society 126 (50), 16487-16498, 2004 | 205 | 2004 |
| Drug target prediction using adverse event report systems: a pharmacogenomic approach M Takarabe, M Kotera, Y Nishimura, S Goto, Y Yamanishi Bioinformatics 28 (18), i611-i618, 2012 | 158 | 2012 |
| Drug side-effect prediction based on the integration of chemical and biological spaces Y Yamanishi, E Pauwels, M Kotera Journal of chemical information and modeling 52 (12), 3284-3292, 2012 | 157 | 2012 |
| DINIES: drug–target interaction network inference engine based on supervised analysis Y Yamanishi, M Kotera, Y Moriya, R Sawada, M Kanehisa, S Goto Nucleic acids research 42 (W1), W39-W45, 2014 | 121 | 2014 |
| The KEGG databases and tools facilitating omics analysis: latest developments involving human diseases and pharmaceuticals M Kotera, M Hirakawa, T Tokimatsu, S Goto, M Kanehisa Next Generation Microarray Bioinformatics: Methods and Protocols, 19-39, 2012 | 117 | 2012 |
| E-zyme: predicting potential EC numbers from the chemical transformation pattern of substrate-product pairs Y Yamanishi, M Hattori, M Kotera, S Goto, M Kanehisa Bioinformatics 25 (12), i179-i186, 2009 | 97 | 2009 |
| Modular architecture of metabolic pathways revealed by conserved sequences of reactions A Muto, M Kotera, T Tokimatsu, Z Nakagawa, S Goto, M Kanehisa Journal of chemical information and modeling 53 (3), 613-622, 2013 | 96 | 2013 |
| WURCS: the Web3 unique representation of carbohydrate structures K Tanaka, KF Aoki-Kinoshita, M Kotera, H Sawaki, S Tsuchiya, N Fujita, ... Journal of chemical information and modeling 54 (6), 1558-1566, 2014 | 80 | 2014 |
| Elucidating the modes of action for bioactive compounds in a cell-specific manner by large-scale chemically-induced transcriptomics M Iwata, R Sawada, H Iwata, M Kotera, Y Yamanishi Scientific reports 7 (1), 40164, 2017 | 71 | 2017 |
| Comparison and improvement of the predictability and interpretability with ensemble learning models in QSPR applications CH Chen, K Tanaka, M Kotera, K Funatsu Journal of cheminformatics 12, 1-16, 2020 | 70 | 2020 |
| Network-based analysis and characterization of adverse drug–drug interactions M Takarabe, D Shigemizu, M Kotera, S Goto, M Kanehisa Journal of chemical information and modeling 51 (11), 2977-2985, 2011 | 70 | 2011 |
| BioHackathon series in 2011 and 2012: penetration of ontology and linked data in life science domains T Katayama, MD Wilkinson, KF Aoki-Kinoshita, S Kawashima, ... Journal of biomedical semantics 5, 1-13, 2014 | 69 | 2014 |
| Benchmarking a Wide Range of Chemical Descriptors for Drug‐Target Interaction Prediction Using a Chemogenomic Approach R Sawada, M Kotera, Y Yamanishi Molecular informatics 33 (11‐12), 719-731, 2014 | 68 | 2014 |
| RPAIR: a reactant-pair database representing chemical changes in enzymatic reactions M Kotera, M Hattori, MA Oh, R Yamamoto, T Komeno, J Yabuzaki, ... Genome Informatics 15 (1), P062, 2004 | 62 | 2004 |
| De novo design of anticancer peptides by ensemble artificial neural networks F Grisoni, CS Neuhaus, M Hishinuma, G Gabernet, JA Hiss, M Kotera, ... Journal of molecular modeling 25, 1-10, 2019 | 57 | 2019 |
| Maize phosphoenolpyruvate carboxylase: mutations at the putative binding site for glucose 6-phosphate caused desensitization and abolished responsiveness to regulatory … A Takahashi-Terada, M Kotera, K Ohshima, T Furumoto, H Matsumura, ... Journal of Biological Chemistry 280 (12), 11798-11806, 2005 | 56 | 2005 |
| GENIES: gene network inference engine based on supervised analysis M Kotera, Y Yamanishi, Y Moriya, M Kanehisa, S Goto Nucleic acids research 40 (W1), W162-W167, 2012 | 48 | 2012 |
| Supervised de novo reconstruction of metabolic pathways from metabolome-scale compound sets M Kotera, Y Tabei, Y Yamanishi, T Tokimatsu, S Goto Bioinformatics 29 (13), i135-i144, 2013 | 43 | 2013 |
Susumu GotoDatabase Center for Life Science, Research Organization of Information and SystemsVerified email at dbcls.rois.ac.jp
