Time-lapse analysis of human embryonic stem cells reveals multiple bottlenecks restricting colony formation and their relief upon culture adaptation I Barbaric, V Biga, PJ Gokhale, M Jones, D Stavish, A Glen, D Coca, ... Stem cell reports 3 (1), 142-155, 2014 | 107 | 2014 |
A PDE variational approach to image denoising and restoration T Barbu, V Barbu, V Biga, D Coca Nonlinear Analysis: Real World Applications 10 (3), 1351-1361, 2009 | 103 | 2009 |
Quantitative single-cell live imaging links HES5 dynamics with cell-state and fate in murine neurogenesis CS Manning, V Biga, J Boyd, J Kursawe, B Ymisson, DG Spiller, ... Nature communications 10 (1), 2835, 2019 | 60 | 2019 |
Stochasticity in the miR-9/Hes1 oscillatory network can account for clonal heterogeneity in the timing of differentiation NE Phillips, CS Manning, T Pettini, V Biga, E Marinopoulou, P Stanley, ... Elife 5, e16118, 2016 | 50 | 2016 |
Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells PWA T F Allison, A JH Smith, K Anastassiadis, J Sloane-Stanley, V Biga, D ... Stem Cell Reports, 2018 | 32 | 2018 |
Dynamic properties of noise and Her6 levels are optimized by miR‐9, allowing the decoding of the Her6 oscillator X Soto, V Biga, J Kursawe, R Lea, P Doostdar, R Thomas, N Papalopulu The EMBO Journal 39 (12), e103558, 2020 | 25 | 2020 |
HES1 protein oscillations are necessary for neural stem cells to exit from quiescence E Marinopoulou, V Biga, N Sabherwal, A Miller, J Desai, AD Adamson, ... IScience 24 (10), 2021 | 21 | 2021 |
A dynamic, spatially periodic, micro‐pattern of HES5 underlies neurogenesis in the mouse spinal cord V Biga, J Hawley, X Soto, E Johns, D Han, H Bennett, AD Adamson, ... Molecular Systems Biology 17 (5), e9902, 2021 | 16 | 2021 |
Human pluripotent stem cells as tools for high-throughput and high-content screening in drug discovery TF Allison, NS Powles-Glover, V Biga, PW Andrews, I Barbaric International Journal of High Throughput Screening, 1-13, 2015 | 10 | 2015 |
Dynamic switching of lateral inhibition spatial patterns J Hawley, C Manning, V Biga, P Glendinning, N Papalopulu Journal of the Royal Society Interface 19 (193), 20220339, 2022 | 6 | 2022 |
HES1 protein oscillations are necessary for neural stem cells to exit from quiescence. iScience 24, 103198 E Marinopoulou, V Biga, N Sabherwal, A Miller, J Desai, AD Adamson, ... Doi, 2021 | 5 | 2021 |
Quantitative, real-time, single cell analysis in tissue reveals expression dynamics of neurogenesis CS Manning, V Biga, J Boyd, J Kursawe, B Ymisson, DG Spiller, ... bioRxiv 10, 373407, 2018 | 3 | 2018 |
NGN3 oscillatory expression controls the timing of human pancreatic endocrine differentiation A Miller, V Biga, A Rowntree, M Chhatriwala, F Woods, E Marinopoulou, ... bioRxiv, 2024.01. 10.574974, 2024 | 1 | 2024 |
miR-9 mediated noise optimization of the her6 oscillator is needed for cell state progression in the Zebrafish hindbrain X Soto, V Biga, J Kursawe, R Lea, P Doostdar, N Papalopulu bioRxiv, 608604, 2019 | 1 | 2019 |
Cell coupling compensates for changes in single-cell Her6 dynamics and provides phenotypic robustness P Doostdar, J Hawley, K Chopra, E Marinopoulou, R Lea, K Arashvand, ... Development 151 (10), 2024 | | 2024 |
Cellular signalling protrusions enable dynamic distant contacts in spinal cord neurogenesis J Hawley, R Lea, V Biga, N Papalopulu, C Manning bioRxiv, 2024.10. 11.617849, 2024 | | 2024 |
Developmental mechanisms understood quantitatively V Biga, TPJ Wyatt, D Pinheiro Development 150 (11), dev201727, 2023 | | 2023 |
A dynamic and spatially periodic micro-pattern of HES5 expression underlies the probability of neuronal differentiation in the mouse spinal cord V Biga, J Hawley, E Johns, D Han, J Kursawe, P Glendinning, ... bioRxiv, 2020.08. 03.234369, 2020 | | 2020 |
A dynamic and spatially periodic micro-pattern of HES5 expression underlies the probability of neuronal differentiation in the mouse spinal cord MCSPN Biga V, Hawley J, Johns E, Han D, Kursawe J, Glendinning P bioRXiv, 2020 | | 2020 |
Information-Theoretic Active Contour Model for Microscopy Image Segmentation Using Texture V Biga, D Coca Computational Intelligence Methods for Bioinformatics and Biostatistics …, 2017 | | 2017 |