Daniel P. Kelly
Daniel P. Kelly
Professor of Medicine, University of Pennsylvania
Cited by
Cited by
PGC-1 coactivators: inducible regulators of energy metabolism in health and disease
BN Finck, DP Kelly
The Journal of clinical investigation 116 (3), 615-622, 2006
Peroxisome proliferator–activated receptor γ coactivator-1 promotes cardiac mitochondrial biogenesis
JJ Lehman, PM Barger, A Kovacs, JE Saffitz, DM Medeiros, DP Kelly
The Journal of clinical investigation 106 (7), 847-856, 2000
Transcriptional regulatory circuits controlling mitochondrial biogenesis and function
DP Kelly, RC Scarpulla
Genes & development 18 (4), 357-368, 2004
The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor α in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes
RB Vega, JM Huss, DP Kelly
Molecular and cellular biology 20 (5), 1868-1876, 2000
Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC‐1
K Baar, AR Wende, TE Jones, M Marison, LA Nolte, MAY Chen, DP Kelly, ...
The FASEB journal 16 (14), 1879-1886, 2002
The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus
BN Finck, JJ Lehman, TC Leone, MJ Welch, MJ Bennett, A Kovacs, X Han, ...
The Journal of clinical investigation 109 (1), 121-130, 2002
PGC-1α deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis
TC Leone, JJ Lehman, BN Finck, PJ Schaeffer, AR Wende, S Boudina, ...
PLoS biology 3 (4), e101, 2005
A critical role for the peroxisome proliferator-activated receptor α (PPARα) in the cellular fasting response: the PPARα-null mouse as a model of fatty acid oxidation disorders
TC Leone, CJ Weinheimer, DP Kelly
Proceedings of the National Academy of Sciences 96 (13), 7473-7478, 1999
Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1
LF Michael, Z Wu, RB Cheatham, P Puigserver, G Adelmant, JJ Lehman, ...
Proceedings of the National Academy of Sciences 98 (7), 3820-3825, 2001
Transcriptional integration of mitochondrial biogenesis
RC Scarpulla, RB Vega, DP Kelly
Trends in Endocrinology & Metabolism 23 (9), 459-466, 2012
Fatty acid oxidation enzyme gene expression is downregulated in the failing heart
MN Sack, TA Rader, S Park, J Bastin, SA McCune, DP Kelly
Circulation 94 (11), 2837-2842, 1996
The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression.
T Gulick, S Cresci, T Caira, DD Moore, DP Kelly
Proceedings of the National Academy of Sciences 91 (23), 11012-11016, 1994
A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content
BN Finck, X Han, M Courtois, F Aimond, JM Nerbonne, A Kovacs, ...
Proceedings of the National Academy of Sciences 100 (3), 1226-1231, 2003
Lipin 1 is an inducible amplifier of the hepatic PGC-1α/PPARα regulatory pathway
BN Finck, MC Gropler, Z Chen, TC Leone, MA Croce, TE Harris, ...
Cell metabolism 4 (3), 199-210, 2006
Mitochondrial energy metabolism in heart failure: a question of balance
JM Huss, DP Kelly
The Journal of clinical investigation 115 (3), 547-555, 2005
The failing heart relies on ketone bodies as a fuel
G Aubert, OJ Martin, JL Horton, L Lai, RB Vega, TC Leone, T Koves, ...
Circulation 133 (8), 698-705, 2016
PPAR signaling in the control of cardiac energy metabolism
PM Barger, DP Kelly
Trends in cardiovascular medicine 10 (6), 238-245, 2000
Altered myocardial fatty acid and glucose metabolism in idiopathic dilated cardiomyopathy
VG Dávila-Román, G Vedala, P Herrero, L De Las Fuentes, JG Rogers, ...
Journal of the American College of Cardiology 40 (2), 271-277, 2002
Deactivation of peroxisome proliferator–activated receptor-α during cardiac hypertrophic growth
PM Barger, JM Brandt, TC Leone, CJ Weinheimer, DP Kelly
The Journal of clinical investigation 105 (12), 1723-1730, 2000
Estrogen-related receptor α directs peroxisome proliferator-activated receptor α signaling in the transcriptional control of energy metabolism in cardiac and skeletal muscle
JM Huss, IP Torra, B Staels, V Giguere, DP Kelly
Molecular and cellular biology 24 (20), 9079-9091, 2004
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