| SARS-CoV-2 disrupts splicing, translation, and protein trafficking to suppress host defenses AK Banerjee, MR Blanco, EA Bruce, DD Honson, LM Chen, A Chow, ... Cell 183 (5), 1325-1339. e21, 2020 | 578 | 2020 |
| A Rab11-and microtubule-dependent mechanism for cytoplasmic transport of influenza A virus viral RNA MJ Amorim, EA Bruce, EKC Read, Á Foeglein, R Mahen, AD Stuart, ... Journal of virology 85 (9), 4143-4156, 2011 | 304 | 2011 |
| The Rab11 pathway is required for influenza A virus budding and filament formation EA Bruce, P Digard, AD Stuart Journal of virology 84 (12), 5848-5859, 2010 | 261 | 2010 |
| Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2 N Drayman, JK DeMarco, KA Jones, SA Azizi, HM Froggatt, K Tan, ... Science 373 (6557), 931-936, 2021 | 212 | 2021 |
| Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy I Ullah, J Prévost, MS Ladinsky, H Stone, M Lu, SP Anand, ... Immunity 54 (9), 2143-2158. e15, 2021 | 190 | 2021 |
| Direct RT-qPCR detection of SARS-CoV-2 RNA from patient nasopharyngeal swabs without an RNA extraction step EA Bruce, ML Huang, GA Perchetti, S Tighe, P Laaguiby, JJ Hoffman, ... PLoS biology 18 (10), e3000896, 2020 | 190 | 2020 |
| Intestinal host response to SARS-CoV-2 infection and COVID-19 outcomes in patients with gastrointestinal symptoms AE Livanos, D Jha, F Cossarini, AS Gonzalez-Reiche, M Tokuyama, ... Gastroenterology 160 (7), 2435-2450. e34, 2021 | 160 | 2021 |
| The major cellular sterol regulatory pathway is required for Andes virus infection J Petersen, MJ Drake, EA Bruce, AM Riblett, CA Didigu, CB Wilen, ... PLoS pathogens 10 (2), e1003911, 2014 | 102 | 2014 |
| Budding of filamentous and non-filamentous influenza A virus occurs via a VPS4 and VPS28-independent pathway EA Bruce, L Medcalf, CM Crump, SL Noton, AD Stuart, HM Wise, D Elton, ... Virology 390 (2), 268-278, 2009 | 75 | 2009 |
| Role of the Rab11 pathway in negative-strand virus assembly. EA Bruce, A Stuart, MW McCaffrey, P Digard Biochemical Society Transactions 40 (6), 2012 | 56 | 2012 |
| Copine A is required for cytokinesis, contractile vacuole function, and development in Dictyostelium CK Damer, M Bayeva, PS Kim, LK Ho, ES Eberhardt, CI Socec, JS Lee, ... Eukaryotic cell 6 (3), 430-442, 2007 | 50 | 2007 |
| The lymphocytic choriomeningitis virus matrix protein PPXY late domain drives the production of defective interfering particles CM Ziegler, P Eisenhauer, EA Bruce, ME Weir, BR King, JP Klaus, ... PLoS pathogens 12 (3), e1005501, 2016 | 47 | 2016 |
| Predicting infectivity: comparing four PCR‐based assays to detect culturable SARS‐CoV‐2 in clinical samples EA Bruce, MG Mills, R Sampoleo, GA Perchetti, ML Huang, HW Despres, ... EMBO molecular medicine 14 (2), e15290, 2022 | 45 | 2022 |
| Drug repurposing screen identifies masitinib as a 3CLpro inhibitor that blocks replication of SARS-CoV-2 in vitro N Drayman, KA Jones, SA Azizi, HM Froggatt, K Tan, NI Maltseva, S Chen, ... BioRxiv, 2020.08. 31.274639, 2020 | 45 | 2020 |
| A map of the arenavirus nucleoprotein-host protein interactome reveals that Junín virus selectively impairs the antiviral activity of double-stranded RNA-activated protein … BR King, D Hershkowitz, PL Eisenhauer, ME Weir, CM Ziegler, J Russo, ... Journal of virology 91 (15), e00763-17, 2017 | 45 | 2017 |
| ‘All In’: a pragmatic framework for COVID‐19 testing and action on a global scale SD Pettit, KR Jerome, D Rouquié, B Mari, P Barbry, Y Kanda, ... EMBO Molecular Medicine 12 (6), e12634, 2020 | 43 | 2020 |
| Kinetics and isotype assessment of antibodies targeting the spike protein receptor‐binding domain of severe acute respiratory syndrome‐coronavirus‐2 in COVID‐19 patients as a … NR Graham, AN Whitaker, CA Strother, AK Miles, D Grier, BD McElvany, ... Clinical & translational immunology 9 (10), e1189, 2020 | 40 | 2020 |
| Measuring infectious SARS-CoV-2 in clinical samples reveals a higher viral titer: RNA ratio for Delta and Epsilon vs. Alpha variants HW Despres, MG Mills, DJ Shirley, MM Schmidt, ML Huang, ... Proceedings of the National Academy of Sciences 119 (5), e2116518119, 2022 | 38 | 2022 |
| Quantitative measurement of infectious virus in SARS-CoV-2 Alpha, Delta and Epsilon variants reveals higher infectivity (viral titer: RNA ratio) in clinical samples containing … HW Despres, MG Mills, DJ Shirley, MM Schmidt, ML Huang, KR Jerome, ... medRxiv, 2021 | 36 | 2021 |
| Release of filamentous and spherical influenza A virus is not restricted by tetherin EA Bruce, TE Abbink, HM Wise, R Rollason, RP Galao, G Banting, SJ Neil, ... Journal of general virology 93 (5), 963-969, 2012 | 35 | 2012 |
Paul DigardProfessor of Virology, the Roslin InstituteVerified email at roslin.ed.ac.uk
