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Bon-Kyoung Koo
Bon-Kyoung Koo
Center for Genome Engineering (CGE), Institute for Basic Science (IBS)
Verified email at ibs.re.kr
Title
Cited by
Cited by
Year
Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients
G Schwank, BK Koo, V Sasselli, JF Dekkers, I Heo, T Demircan, N Sasaki, ...
Cell stem cell 13 (6), 653-658, 2013
16282013
Human organoids: model systems for human biology and medicine
J Kim, BK Koo, JA Knoblich
Nature Reviews Molecular Cell Biology 21 (10), 571-584, 2020
15232020
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
W De Lau, N Barker, TY Low, BK Koo, VSW Li, H Teunissen, P Kujala, ...
Nature 476 (7360), 293-297, 2011
14112011
Human primary liver cancer–derived organoid cultures for disease modeling and drug screening
L Broutier, G Mastrogiovanni, MMA Verstegen, HE Francies, LM Gavarrķ, ...
Nature medicine 23 (12), 1424-1435, 2017
11932017
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
BK Koo, M Spit, I Jordens, TY Low, DE Stange, M Van De Wetering, ...
Nature 488 (7413), 665-669, 2012
9872012
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent ‘+ 4’cell markers
J Muņoz, DE Stange, AG Schepers, M Van De Wetering, BK Koo, ...
The EMBO journal 31 (14), 3079-3091, 2012
8292012
Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation
L Broutier, A Andersson-Rolf, CJ Hindley, SF Boj, H Clevers, BK Koo, ...
Nature protocols 11 (9), 1724-1743, 2016
7002016
Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium
MY Turco, L Gardner, J Hughes, T Cindrova-Davies, MJ Gomez, L Farrell, ...
Nature cell biology 19 (5), 568-577, 2017
5572017
Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium
DE Stange, BK Koo, M Huch, G Sibbel, O Basak, A Lyubimova, P Kujala, ...
Cell 155 (2), 357-368, 2013
5412013
Modeling mouse and human development using organoid cultures
M Huch, BK Koo
Development 142 (18), 3113-3125, 2015
5382015
Inflammatory signals induce AT2 cell-derived damage-associated transient progenitors that mediate alveolar regeneration
J Choi, JE Park, G Tsagkogeorga, M Yanagita, BK Koo, N Han, JH Lee
Cell stem cell 27 (3), 366-382. e7, 2020
3672020
Controlled gene expression in primary Lgr5 organoid cultures
BK Koo, DE Stange, T Sato, W Karthaus, HF Farin, M Huch, JH Van Es, ...
Nature methods 9 (1), 81-83, 2012
3642012
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal
JH van Es, A Haegebarth, P Kujala, S Itzkovitz, BK Koo, SF Boj, J Korving, ...
Molecular and cellular biology, 2012
3032012
Ascl2 acts as an R-spondin/Wnt-responsive switch to control stemness in intestinal crypts
J Schuijers, JP Junker, M Mokry, P Hatzis, BK Koo, V Sasselli, ...
Cell stem cell 16 (2), 158-170, 2015
2882015
Mind bomb 1 is essential for generating functional Notch ligands to activate Notch
BK Koo, HS Lim, R Song, MJ Yoon, KJ Yoon, JS Moon, YW Kim, M Kwon, ...
Oxford University Press for The Company of Biologists Limited 132 (15), 3459 …, 2005
2852005
Human gastric cancer modelling using organoids
T Seidlitz, SR Merker, A Rothe, F Zakrzewski, C von Neubeck, ...
Gut 68 (2), 207-217, 2019
2822019
ER stress causes rapid loss of intestinal epithelial stemness through activation of the unfolded protein response
J Heijmans, JFL de Jeude, BK Koo, SL Rosekrans, MCB Wielenga, ...
Cell reports 3 (4), 1128-1139, 2013
2712013
Divergent routes toward Wnt and R-spondin niche independency during human gastric carcinogenesis
K Nanki, K Toshimitsu, A Takano, M Fujii, M Shimokawa, Y Ohta, ...
Cell 174 (4), 856-869. e17, 2018
2692018
DNA methylation and transcription patterns in intestinal epithelial cells from pediatric patients with inflammatory bowel diseases differentiate disease subtypes and associate …
KJ Howell, J Kraiczy, KM Nayak, M Gasparetto, A Ross, C Lee, TN Mak, ...
Gastroenterology 154 (3), 585-598, 2018
2692018
A crucial role of WW45 in developing epithelial tissues in the mouse
JH Lee, TS Kim, TH Yang, BK Koo, SP Oh, KP Lee, HJ Oh, SH Lee, ...
The EMBO journal 27 (8), 1231-1242, 2008
2282008
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