Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36 TK Means, E Mylonakis, E Tampakakis, RA Colvin, E Seung, L Puckett, ... Journal of Experimental Medicine 206 (3), 637-653, 2009 | 302 | 2009 |
Adenylyl Cyclase Functions Downstream of the Gα Protein Gpa1 and Controls Mating and Pathogenicity of Cryptococcus neoformans JA Alspaugh, R Pukkila-Worley, T Harashima, LM Cavallo, D Funnell, ... Eukaryotic cell 1 (1), 75-84, 2002 | 248 | 2002 |
Candida albicans Hyphal Formation and Virulence Assessed Using a Caenorhabditis elegans Infection Model R Pukkila-Worley, AY Peleg, E Tampakakis, E Mylonakis Eukaryotic cell 8 (11), 1750-1758, 2009 | 236 | 2009 |
Immune defense mechanisms in the Caenorhabditis elegans intestinal epithelium R Pukkila-Worley, FM Ausubel Current opinion in immunology 24 (1), 3-9, 2012 | 218 | 2012 |
Transcriptional Network of Multiple Capsule and Melanin Genes Governed by the Cryptococcus neoformans Cyclic AMP Cascade R Pukkila-Worley, QD Gerrald, PR Kraus, MJ Boily, MJ Davis, SS Giles, ... Eukaryotic cell 4 (1), 190-201, 2005 | 210 | 2005 |
Candida albicans Infection of Caenorhabditis elegans Induces Antifungal Immune Defenses R Pukkila-Worley, FM Ausubel, E Mylonakis PLoS pathogens 7 (6), e1002074, 2011 | 178 | 2011 |
Epidemiology and management of cryptococcal meningitis: developments and challenges R Pukkila-Worley, E Mylonakis Expert opinion on pharmacotherapy 9 (4), 551-560, 2008 | 113 | 2008 |
Stimulation of Host Immune Defenses by a Small Molecule Protects C. elegans from Bacterial Infection R Pukkila-Worley, R Feinbaum, NV Kirienko, J Larkins-Ford, AL Conery, ... PLoS genetics 8 (6), e1002733, 2012 | 102 | 2012 |
Chromosomal Translocation and Segmental Duplication in Cryptococcus neoformans JA Fraser, JC Huang, R Pukkila-Worley, JA Alspaugh, TG Mitchell, ... Eukaryotic cell 4 (2), 401-406, 2005 | 78 | 2005 |
Aberrant Activation of p38 MAP Kinase-Dependent Innate Immune Responses Is Toxic to Caenorhabditis elegans HK Cheesman, RL Feinbaum, J Thekkiniath, RH Dowen, AL Conery, ... G3: Genes, Genomes, Genetics 6 (3), 541-549, 2016 | 74 | 2016 |
Mitochondrial UPR repression during Pseudomonas aeruginosa infection requires the bZIP protein ZIP-3 P Deng, N Uma Naresh, Y Du, LT Lamech, J Yu, LJ Zhu, ... Proceedings of the National Academy of Sciences 116 (13), 6146-6151, 2019 | 71 | 2019 |
Association of low birth weight and placental malarial infection in Nigeria DN Aribodor, OC Nwaorgu, CI Eneanya, I Okoli, R Pukkila-Worley, ... The Journal of Infection in Developing Countries 3 (08), 620-623, 2009 | 71 | 2009 |
The fatty acid oleate is required for innate immune activation and pathogen defense in Caenorhabditis elegans SM Anderson, HK Cheesman, ND Peterson, JE Salisbury, AA Soukas, ... PLoS pathogens 15 (6), e1007893, 2019 | 70 | 2019 |
Surveillance Immunity: An Emerging Paradigm of Innate Defense Activation in Caenorhabditis elegans R Pukkila-Worley PLoS pathogens 12 (9), e1005795, 2016 | 66 | 2016 |
The evolutionarily conserved mediator subunit MDT-15/MED15 links protective innate immune responses and xenobiotic detoxification R Pukkila-Worley, RL Feinbaum, DL McEwan, AL Conery, FM Ausubel PLoS pathogens 10 (5), e1004143, 2014 | 63 | 2014 |
Innate immunity in the C. elegans intestine is programmed by a neuronal regulator of AWC olfactory neuron development KJ Foster, HK Cheesman, P Liu, ND Peterson, SM Anderson, ... Cell reports 31 (1), 2020 | 57 | 2020 |
Cyclic AMP signaling in Cryptococcus neoformans R Pukkila-Worley, JA Alspaugh FEMS yeast research 4 (4-5), 361-367, 2004 | 55 | 2004 |
The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegans ND Peterson, HK Cheesman, P Liu, SM Anderson, KJ Foster, R Chhaya, ... PLoS genetics 15 (1), e1007935, 2019 | 54 | 2019 |
Antifungal drug discovery through the study of invertebrate model hosts R Pukkila-Worley, E Holson, F Wagner, E Mylonakis Current medicinal chemistry 16 (13), 1588-1595, 2009 | 52 | 2009 |
Caenorhabditis elegans in high-throughput screens for anti-infective compounds ND Peterson, R Pukkila-Worley Current opinion in immunology 54, 59-65, 2018 | 50 | 2018 |