| Nucleosomes can form a polar barrier to transcript elongation by RNA polymerase II VA Bondarenko, LM Steele, A Újvári, DA Gaykalova, OI Kulaeva, ... Molecular cell 24 (3), 469-479, 2006 | 316 | 2006 |
| Ribosome-targeting antibiotics: modes of action, mechanisms of resistance, and implications for drug design J Lin, D Zhou, TA Steitz, YS Polikanov, MG Gagnon Annual review of biochemistry 87 (1), 451-478, 2018 | 309 | 2018 |
| Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly YS Polikanov, SV Melnikov, D Söll, TA Steitz Nature structural & molecular biology 22 (4), 342-344, 2015 | 258 | 2015 |
| How hibernation factors RMF, HPF, and YfiA turn off protein synthesis YS Polikanov, GM Blaha, TA Steitz Science 336 (6083), 915-918, 2012 | 250 | 2012 |
| A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome YS Polikanov, TA Steitz, CA Innis Nature structural & molecular biology 21 (9), 787-793, 2014 | 242 | 2014 |
| Pseudouridinylation of mRNA coding sequences alters translation DE Eyler, MK Franco, Z Batool, MZ Wu, ML Dubuke, M Dobosz-Bartoszek, ... Proceedings of the National Academy of Sciences 116 (46), 23068-23074, 2019 | 180 | 2019 |
| Structural and evolutionary insights into ribosomal RNA methylation PV Sergiev, NA Aleksashin, AA Chugunova, YS Polikanov, OA Dontsova Nature chemical biology 14 (3), 226-235, 2018 | 160 | 2018 |
| Distant activation of transcription: mechanisms of enhancer action OI Kulaeva, EV Nizovtseva, YS Polikanov, SV Ulianov, VM Studitsky Molecular and cellular biology 32 (24), 4892-4897, 2012 | 149 | 2012 |
| A synthetic antibiotic class overcoming bacterial multidrug resistance MJ Mitcheltree, A Pisipati, EA Syroegin, KJ Silvestre, D Klepacki, ... Nature 599 (7885), 507-512, 2021 | 141 | 2021 |
| Odilorhabdins, antibacterial agents that cause miscoding by binding at a new ribosomal site L Pantel, T Florin, M Dobosz-Bartoszek, E Racine, M Sarciaux, M Serri, ... Molecular cell 70 (1), 83-94. e7, 2018 | 139 | 2018 |
| The mechanisms of action of ribosome-targeting peptide antibiotics YS Polikanov, NA Aleksashin, B Beckert, DN Wilson Frontiers in molecular biosciences 5, 48, 2018 | 123 | 2018 |
| Amicoumacin A inhibits translation by stabilizing mRNA interaction with the ribosome YS Polikanov, IA Osterman, T Szal, VN Tashlitsky, MV Serebryakova, ... Molecular cell 56 (4), 531-540, 2014 | 110 | 2014 |
| Insights into RNA binding by the anticancer drug cisplatin from the crystal structure of cisplatin-modified ribosome SV Melnikov, D Söll, TA Steitz, YS Polikanov Nucleic acids research 44 (10), 4978-4987, 2016 | 101 | 2016 |
| Distinct tRNA accommodation intermediates observed on the ribosome with the antibiotics hygromycin A and A201A YS Polikanov, AL Starosta, MF Juette, RB Altman, DS Terry, W Lu, ... Molecular cell 58 (5), 832-844, 2015 | 98 | 2015 |
| In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii M Juhas, E Widlake, J Teo, DL Huseby, JM Tyrrell, YS Polikanov, O Ercan, ... Journal of Antimicrobial Chemotherapy 74 (4), 944-952, 2019 | 94 | 2019 |
| Structure of Erm-modified 70S ribosome reveals the mechanism of macrolide resistance MS Svetlov, EA Syroegin, EV Aleksandrova, GC Atkinson, ST Gregory, ... Nature chemical biology 17 (4), 412-420, 2021 | 85 | 2021 |
| Binding and action of amino acid analogs of chloramphenicol upon the bacterial ribosome AG Tereshchenkov, M Dobosz-Bartoszek, IA Osterman, J Marks, ... Journal of molecular biology 430 (6), 842-852, 2018 | 70 | 2018 |
| Klebsazolicin inhibits 70S ribosome by obstructing the peptide exit tunnel M Metelev, IA Osterman, D Ghilarov, NF Khabibullina, A Yakimov, ... Nature chemical biology 13 (10), 1129-1136, 2017 | 70 | 2017 |
| High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition MS Svetlov, E Plessa, CW Chen, A Bougas, MG Krokidis, GP Dinos, ... Rna 25 (5), 600-606, 2019 | 65 | 2019 |
| Tetracenomycin X inhibits translation by binding within the ribosomal exit tunnel IA Osterman, M Wieland, TP Maviza, KA Lashkevich, DA Lukianov, ... Nature chemical biology 16 (10), 1071-1077, 2020 | 62 | 2020 |
Gregor BlahaAssistant Professor of Biochemistry, UC RiversideVerified email at ucr.edu
