Stuart Milstein
Stuart Milstein
Senda Biosciences
Verified email at - Homepage
Cited by
Cited by
Towards a proteome-scale map of the human protein–protein interaction network
JF Rual, K Venkatesan, T Hao, T Hirozane-Kishikawa, A Dricot, N Li, ...
Nature 437 (7062), 1173-1178, 2005
A map of the interactome network of the metazoan C. elegans
S Li, CM Armstrong, N Bertin, H Ge, S Milstein, M Boxem, PO Vidalain, ...
Science 303 (5657), 540-543, 2004
Multivalent N-Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing
JK Nair, JLS Willoughby, A Chan, K Charisse, MR Alam, Q Wang, ...
Journal of the American Chemical Society 136 (49), 16958-16961, 2014
Therapeutic siRNA silencing in inflammatory monocytes in mice
F Leuschner, P Dutta, R Gorbatov, TI Novobrantseva, JS Donahoe, ...
Nature biotechnology 29 (11), 1005-1010, 2011
A conserved checkpoint pathway mediates DNA damage–induced apoptosis and cell cycle arrest in C. elegans
A Gartner, S Milstein, S Ahmed, J Hodgkin, MO Hengartner
Molecular cell 5 (3), 435-443, 2000
Edgetic perturbation models of human inherited disorders
Q Zhong, N Simonis, QR Li, B Charloteaux, F Heuze, N Klitgord, S Tam, ...
Molecular systems biology 5 (1), 321, 2009
Acetyl CoA carboxylase inhibition reduces hepatic steatosis but elevates plasma triglycerides in mice and humans: a bedside to bench investigation
CW Kim, C Addy, J Kusunoki, NN Anderson, S Deja, X Fu, SC Burgess, ...
Cell metabolism 26 (2), 394-406. e6, 2017
Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network
N Simonis, JF Rual, AR Carvunis, M Tasan, I Lemmens, ...
Nature methods 6 (1), 47-54, 2009
hORFeome v3. 1: a resource of human open reading frames representing over 10,000 human genes
P Lamesch, N Li, S Milstein, C Fan, T Hao, G Szabo, Z Hu, K Venkatesan, ...
Genomics 89 (3), 307-315, 2007
Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis
ER Hofmann, S Milstein, SJ Boulton, M Ye, JJ Hofmann, L Stergiou, ...
Current biology 12 (22), 1908-1918, 2002
An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia
A Sehgal, S Barros, L Ivanciu, B Cooley, J Qin, T Racie, J Hettinger, ...
Nature medicine 21 (5), 492-497, 2015
Advanced siRNA designs further improve in vivo performance of GalNAc-siRNA conjugates
DJ Foster, CR Brown, S Shaikh, C Trapp, MK Schlegel, K Qian, A Sehgal, ...
Molecular Therapy 26 (3), 708-717, 2018
A protein domain-based interactome network for C. elegans early embryogenesis
M Boxem, Z Maliga, N Klitgord, N Li, I Lemmens, M Mana, ...
Cell 134 (3), 534-545, 2008
An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe−/− mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia
PJ Schmidt, I Toudjarska, AK Sendamarai, T Racie, S Milstein, ...
Blood, The Journal of the American Society of Hematology 121 (7), 1200-1208, 2013
siRNA Conjugates Carrying Sequentially Assembled Trivalent N-Acetylgalactosamine Linked Through Nucleosides Elicit Robust Gene Silencing In Vivo in …
S Matsuda, K Keiser, JK Nair, K Charisse, RM Manoharan, P Kretschmer, ...
ACS chemical biology 10 (5), 1181-1187, 2015
Hepatocyte‐Specific Delivery of siRNAs Conjugated to Novel Non‐nucleosidic Trivalent N‐Acetylgalactosamine Elicits Robust Gene Silencing in Vivo
KG Rajeev, JK Nair, M Jayaraman, K Charisse, N Taneja, J O'Shea, ...
ChemBioChem 16 (6), 903-908, 2015
Systematic interactome mapping and genetic perturbation analysis of a C. elegans TGF-β signaling network
M Tewari, PJ Hu, JS Ahn, N Ayivi-Guedehoussou, PO Vidalain, S Li, ...
Molecular cell 13 (4), 469-482, 2004
C. elegans ORFeome version 3.1: increasing the coverage of ORFeome resources with improved gene predictions
P Lamesch, S Milstein, T Hao, J Rosenberg, N Li, R Sequerra, S Bosak, ...
Genome research 14 (10b), 2064-2069, 2004
Systemic RNAi-mediated gene silencing in nonhuman primate and rodent myeloid cells
TI Novobrantseva, A Borodovsky, J Wong, B Klebanov, M Zafari, K Yucius, ...
Molecular Therapy-Nucleic Acids 1, 2012
Preclinical development of a subcutaneous ALAS1 RNAi therapeutic for treatment of hepatic porphyrias using circulating RNA quantification
A Chan, A Liebow, M Yasuda, L Gan, T Racie, M Maier, S Kuchimanchi, ...
Molecular Therapy-Nucleic Acids 4, 2015
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