Amyloid-β-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Aβ peptide. Implications for the pathogenesis of Alzheimer's disease MC Dinamarca, JP Sagal, RA Quintanilla, JA Godoy, MS Arrázola, ... Molecular neurodegeneration 5 (1), 1-15, 2010 | 142 | 2010 |
Canonical Wnt signaling protects hippocampal neurons from Aβ oligomers: role of non-canonical Wnt-5a/Ca2+ in mitochondrial dynamics C Silva-Alvarez, M Arrazola, JA Godoy, D Ordenes, NC Inestrosa Frontiers in cellular neuroscience 7, 97, 2013 | 107 | 2013 |
Nicotine prevents synaptic impairment induced by amyloid-β oligomers through α7-nicotinic acetylcholine receptor activation NC Inestrosa, JA Godoy, JY Vargas, MS Arrazola, JA Rios, FJ Carvajal, ... Neuromolecular medicine 15 (3), 549-569, 2013 | 102 | 2013 |
Is L-methionine a trigger factor for Alzheimer’s-like neurodegeneration?: changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral … C Tapia-Rojas, CB Lindsay, C Montecinos-Oliva, MS Arrazola, ... Molecular neurodegeneration 10 (1), 1-17, 2015 | 100 | 2015 |
Calcium/calmodulin‐dependent protein kinase type IV is a target gene of the Wnt/β‐catenin signaling pathway MS Arrázola, L Varela‐Nallar, M Colombres, EM Toledo, F Cruzat, ... Journal of cellular physiology 221 (3), 658-667, 2009 | 96 | 2009 |
How the Wnt signaling pathway protects from neurodegeneration: the mitochondrial scenario MS Arrázola, C Silva-Alvarez, NC Inestrosa Frontiers in cellular neuroscience 9, 166, 2015 | 86 | 2015 |
Wnt-5a ligand modulates mitochondrial fission-fusion in rat hippocampal neurons JA Godoy, MS Arrázola, D Ordenes, C Silva-Alvarez, N Braidy, ... Journal of Biological Chemistry 289 (52), 36179-36193, 2014 | 69 | 2014 |
Release of acetylcholinesterase (AChE) from β-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice MC Dinamarca, M Arrázola, E Toledo, WF Cerpa, J Hancke, NC Inestrosa Chemico-biological interactions 175 (1-3), 142-149, 2008 | 60 | 2008 |
Axonal degeneration is mediated by necroptosis activation MS Arrázola, C Saquel, RJ Catalán, SA Barrientos, DE Hernandez, ... Journal of Neuroscience 39 (20), 3832-3844, 2019 | 59 | 2019 |
Wnt signaling prevents the Aβ oligomer-induced mitochondrial permeability transition pore opening preserving mitochondrial structure in hippocampal neurons MS Arrázola, E Ramos-Fernández, P Cisternas, D Ordenes, NC Inestrosa PloS one 12 (1), e0168840, 2017 | 53 | 2017 |
Mitochondria in developmental and adult neurogenesis MS Arrázola, T Andraini, M Szelechowski, L Mouledous, ... Neurotoxicity Research 36 (2), 257-267, 2019 | 49 | 2019 |
Amplifying mitochondrial function rescues adult neurogenesis in a mouse model of Alzheimer's disease K Richetin, M Moulis, A Millet, MS Arrŕzola, T Andraini, J Hua, N Davezac, ... Neurobiology of disease 102, 113-124, 2017 | 42 | 2017 |
WASP-1, a canonical Wnt signaling potentiator, rescues hippocampal synaptic impairments induced by Aβ oligomers JY Vargas, J Ahumada, MS Arrázola, M Fuenzalida, NC Inestrosa Experimental neurology 264, 14-25, 2015 | 40 | 2015 |
The Protein Oxidation Repair Enzyme Methionine Sulfoxide Reductase A Modulates Aβ Aggregation and Toxicity In Vivo AN Minniti, MS Arrazola, M Bravo-Zehnder, F Ramos, NC Inestrosa, ... Antioxidants & redox signaling 22 (1), 48-62, 2015 | 22 | 2015 |
Monitoring mitochondrial membranes permeability in live neurons and mitochondrial swelling through electron microscopy analysis MS Arrázola, NC Inestrosa Neuronal Cell Death, 87-97, 2015 | 21 | 2015 |
Compartmentalized necroptosis activation in excitotoxicity-induced axonal degeneration: a novel mechanism implicated in neurodegenerative disease pathology MS Arrazola, FA Court Neural regeneration research 14 (8), 1385, 2019 | 16 | 2019 |
Hormetic-like effects of L-homocysteine on synaptic structure, function, and Aβ aggregation C Montecinos-Oliva, MS Arrázola, C Jara, C Tapia-Rojas, NC Inestrosa Pharmaceuticals 13 (2), 24, 2020 | 15 | 2020 |
The metabolomic signature of Opa1 deficiency in rat primary cortical neurons shows aspartate/glutamate depletion and phospholipids remodeling JMC de La Barca, MS Arrázola, C Bocca, L Arnauné-Pelloquin, O Iuliano, ... Scientific reports 9 (1), 1-8, 2019 | 13 | 2019 |
Necroptosis inhibition counteracts neurodegeneration, memory decline, and key hallmarks of aging, promoting brain rejuvenation MS Arrázola, M Lira, F Véliz‐Valverde, G Quiroz, S Iqbal, SL Eaton, ... Aging Cell 22 (5), e13814, 2023 | 11 | 2023 |
Wnt5a promotes hippocampal postsynaptic development and GluN2B-induced expression via the eIF2α HRI kinase E Ramos-Fernández, MS Arrázola, CA Oliva, SB Arredondo, ... Scientific reports 11 (1), 1-20, 2021 | 9 | 2021 |